Living With Crohn Disease Glossary of Medical Terms

Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Anatomy: The study of form. Gross anatomy involves structures that can be seen with the naked eye. It is as opposed to microscopic anatomy (or histology) which involves structures seen under the microscope. Traditionally, both gross and microscopic anatomy have been studied in the first year of medical school in the U.S. The most celebrated textbook of anatomy in the English-speaking world is Gray's Anatomy, still a useful reference book. The word "anatomy" comes from the Greek ana- meaning up or through + tome meaning a cutting. Anatomy was once a "cutting up" because the structure of the body was originally learned through dissecting it, cutting it up. The abbreviation for anatomy is anat.
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Anxiety: A feeling of apprehension and fear characterized by physical symptoms such as palpitations , sweating, and feelings of stress . Anxiety disorders are serious medical illnesses that affect approximately 19 million American adults. These disorders fill people's lives with overwhelming anxiety and fear. Unlike the relatively mild, brief anxiety caused by a stressful event such as a business presentation or a first date, anxiety disorders are chronic, relentless, and can grow progressively worse if not treated.
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Autoimmune: Pertaining to autoimmunity, a misdirected immune response that occurs when the immune system goes awry and attacks the body itself.
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Autoimmune disease: An illness that occurs when the body tissues are attacked by its own immune system . The immune system is a complex organization within the body that is designed normally to "seek and destroy" invaders of the body, including infectious agents. Patients with autoimmune diseases frequently have unusual antibodies circulating in their blood that target their own body tissues.
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Autoimmunity: A misdirected immune response that occurs when the immune system goes awry and attacks the body itself.
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Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Bile: Bile is a yellow-green fluid that is made by the liver, stored in the gallbladder and passes through the common bile duct into the duodenum where it helps digest fat. The principal components of bile are cholesterol, bile salts, and the pigment bilirubin.
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Bowel: Another name for the intestine . The small bowel and the large bowel are the small intestine and large intestine , respectively.
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Chronic illness: An illness that persists for a long period of time. The term "chronic" comes from the Greek chronos, time and means lasting a long time.
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Colectomy: Surgery during which all or part of the colon (also called the large intestine) is removed.
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Colitis: Inflammation of the large intestine (the colon). There are many forms of colitis , including ulcerative colitis , Crohn's disease , infectious, pseudomembranous, and spastic. For example, intermittent rectal bleeding , crampy abdominal pain and diarrhea can be symptoms of ulcerative colitis. Diagnosis can be made by barium enema, but direct visualization (sigmoidoscopy or colonoscopy ) is the most accurate test. Long-standing ulcerative colitis increases the risk for colon cancer . Ulcerative colitis can also be associated with inflammation in joints, spine, skin, eyes, the liver and its bile ducts. Treatment of ulcerative colitis can involve medications and surgery.
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Colitis: Inflammation of the large intestine (the colon). There are many forms of colitis , including ulcerative colitis , Crohn's disease , infectious, pseudomembranous, and spastic. For example, intermittent rectal bleeding , crampy abdominal pain and diarrhea can be symptoms of ulcerative colitis. Diagnosis can be made by barium enema, but direct visualization (sigmoidoscopy or colonoscopy ) is the most accurate test. Long-standing ulcerative colitis increases the risk for colon cancer . Ulcerative colitis can also be associated with inflammation in joints, spine, skin, eyes, the liver and its bile ducts. Treatment of ulcerative colitis can involve medications and surgery.
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Colon: The part of the large intestine that runs from the cecum to the rectum as a long hollow tube that serves to remove water from digested food and let the remaining material, solid waste called stool , move through it to the rectum and leave the body through the anus . .
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Colonoscopy: A procedure in which a long flexible viewing tube (a colonoscope) is threaded up through the rectum for the purpose of inspecting the entire colon and rectum and, if there is an abnormality, taking a biopsy of it or removing it. The colonoscopy procedure requires a thorough bowel cleansing to assure a clear view of the lining. Called also coloscopy.
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Colostomy: An alternative exit from the colon created to divert waste through a hole in the colon and through the wall of the abdomen. A colostomy is commonly performed by severing the colon to attach the end leading to the stomach to the skin through the wall of the abdomen. The end of the colon that leads to the rectum is closed off and becomes dormant. This is known as a "Hartmann's Colostomy". There are other types of colostomy procedures, but this one is the most common. Usually a colostomy is performed for infection, blockage, or in rare instances, severe trauma of the colon. This is not an operation to be taken lightly. It demands the close attention of both patient and doctor. A colostomy is often performed so that an infection can be stopped and/or the affected colon tissues can heal.
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Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.
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Crohn colitis: Crohn disease involving only the large intestine (colon).
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Crohn's disease : A chronic inflammatory disease, primarily involving the small and large intestine, but which can affect other parts of the digestive system as well. It is named for Burrill Crohn, the American gastroenterologist who first described the disease in 1932.
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Cure: 1. To heal, to make well, to restore to good health. Cures are easy to claim and, all too often, difficult to confirm.
2. A time without recurrence of a disease so that the risk of recurrence is small, as in the 5-year cure rate for malignant melanoma .
3. Particularly in the past, a course of treatment. For example, take a cure at a spa.
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Depression : An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression.
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Diabetes: Refers to diabetes mellitus or, less often, to diabetes insipidus . Diabetes mellitus and diabetes insipidus share the name "diabetes" because they are both conditions characterized by excessive urination (polyuria).
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Diarrhea : A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation . The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
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Endoscopy: Endoscopy is a broad term used to described examining the inside of the body using a lighted, flexible instrument called an endoscope. In general, an endoscope is introduced into the body through a natural opening like the mouth or anus. Although endoscopy can include examination of other organs, the most common endoscopic procedures evaluate the esophagus (swallowing tube), stomach, and portions of the intestine.
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Gastroenteritis: Inflammation of the stomach and the intestines. Can cause nausea and vomiting and/or diarrhea . Gastroenteritis has numerous causes: including infectious organisms (viruses, bacteria, etc.), food poisoning , and stress.
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Gastroenterology: The medical specialty devoted to the study, diagnosis and treatment of disorders of the digestive system . These disorders may affect the esophagus (swallowing tube), stomach , small intestine , large intestine ( colon ), rectum , liver , gallbladder , or pancreas .
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Genetic: Having to do with genes and genetic information.
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Granulomatous colitis: Crohn's disease of the colon (the large intestine).
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Hepatology: The field of liver disease . The liver is the body's largest organ and hepatology is a large field. It includes, but is not limited to, the study of acute and chronic hepatitis , viral hepatitis , cirrhosis , genetic and metabolic liver diseases and their complications, liver cancer, liver transplantation, drug metabolism (which depends largely upon the liver), and immunology as it pertains to the liver.
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Ileostomy: An opening into the ileum, part of the small intestine, from the outside of the body. An ileostomy provides a new path for waste material to leave the body after part of the intestine has been removed. An opening into the ileum, part of the small intestine, from the outside of the body. An ileostomy provides a new path for waste material to leave the body after part of the intestine has been removed.
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Immune: Protected against infection. The Latin immunis means free, exempt.
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Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
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Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response .
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Inflammatory bowel disease: A group of chronic intestinal diseases characterized by inflammation of the bowel -- the large or small intestine. The most common types of inflammatory bowel disease (IBD) are ulcerative colitis and Crohn disease .
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Internal medicine: A medical specialty dedicated to the diagnosis and medical treatment of adults. A physician who specializes in internal medicine is referred to as an internist. A minimum of seven years of medical school and postgraduate training are focused on learning the prevention, diagnosis, and treatment of diseases of adults. Subspecialties of internal medicine include allergy and immunology, cardiology (heart), endocrinology (hormone disorders), hematology (blood disorders), infectious diseases, gastroenterology (diseases of the gut), nephrology (kidney diseases), oncology (cancer), pulmonology (lung disorders), and rheumatology ( arthritis and musculoskeletal disorders).
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Intestine: The long, tubelike organ in the abdomen that completes the process of digestion. It consists of the small and large intestines.
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Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.

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Large intestine: Comes after the small intestine. Large because it is wider than the small intestine.
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Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.

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Malabsorption: The impaired absorption by the intestines of nutrients from food. Malabsorption can be specific and involve sugars, fats , proteins , or vitamins . Alternatively, malabsorption can be general and nonspecific.
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Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.
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Nasogastric: Referring to the passage from the nose to the stomach. A nasogastric tube is one that is passed through the nose (via the nasopharynx and esophagus) down into the stomach. The abbreviation for nasogastric is NG. The tube is an NG tube.
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Nasogastric tube: A tube that is passed through the nose and down through the nasopharynx and esophagus into the stomach . Abbreviated NG tube . It is a flexible tube made of rubber or plastic, and it has bidirectional potential. It can be used to remove the contents of the stomach, including air, to decompress the stomach, or to remove small solid objects and fluid, such as poison , from the stomach. An NG tube can also be used to put substances into the stomach, and so it may be used to place nutrients directly into the stomach when a patient cannot take food or drink by mouth.
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NG tube: See: Nasogastric tube .
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Nutrition : 1) The science or practice of taking in and utilizing foods. 2) A nourishing substance, such as nutritional solutions delivered to hospitalized patients via an IV or IG tube.
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Ostomy: An operation to create an opening from an area inside the body to the outside.
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PA-C: Physician Assistant - Certified.
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Pediatric: Pertaining to children.
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Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.
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Regional enteritis: Crohn's disease , a chronic inflammatory disease of the intestine primarily in the small and large intestines but which can occur anywhere in the digestive system between the mouth and the anus.
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Small intestine: The part of the digestive tract that extends from the stomach to the large intestine.
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Stoma: An opening into the body from the outside created by a surgeon.
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Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine.
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Stress: Forces from the outside world impinging on the individual. Stress is a normal part of life that can help us learn and grow. Conversely, stress can cause us significant problems.
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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Terminal ileitis: Crohn's disease , a chronic inflammatory disease of the intestine involving only the end of the small intestine (the terminal ileum). Crohn's disease affects primarily the small and large intestines but which can occur anywhere in the digestive system between the mouth and the anus. Named after Burrill Crohn who described the disease in 1932. The disease often strikes persons in their teens or early twenties. It tends to be chronic, recurrent with periods of remission and exacerbation. In the early stages, It causes small scattered shallow crater-like areas (erosions) called aphthous ulcers in the inner surface of the bowel. With time, deeper and larger ulcers develop, causing scarring and stiffness of the bowel and the bowel becomes increasingly narrowed, leading to obstruction. Deep ulcers can puncture holes in the bowel wall, leading to infection in the abdominal cavity (peritonitis) and in adjacent organs Abdominal pain , diarrhea , vomiting, fever , and weight loss can be symptoms. Crohn's disease can be associated with reddish tender skin nodules, and inflammation of the joints, spine, eyes, and liver. Diagnosis is by barium enema, barium x-ray of the small bowel, and colonoscopy. Treatment includes medications for inflammation, immune suppression, antibiotics, or surgery.
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Trigger: Something that either sets off a disease in people who are genetically predisposed to developing the disease, or that causes a certain symptom to occur in a person who has a disease. For example, sunlight can trigger rashes in people with lupus .
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Ulcer: An area of tissue erosion, for example, of the skin or lining of the gastrointestinal (GI) tract. Due to the erosion, an ulcer is concave. It is always depressed below the level of the surrounding tissue.
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Ulcerative colitis : A relatively common disease that causes inflammation of the large intestine (the colon). The cause is unknown.
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Virus: A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with errors (mutations)-this ability to mutate is responsible for the ability of some viruses to change slightly in each infected person, making treatment more difficult.
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