Loratadine is a nonprescription (over-the-counter) antihistamine. It is a second-generation antihistamine and selectively inhibits binding of histamine to type 1 histamine receptors, thereby reducing the incidence of sedation experienced with older antihistamines. Antihistamines compete with histamine for histamine receptor sites. By occupying the histamine receptor sites, they prevent histamine from its actions.
Loratadine is indicated for adults and children 2 years or older for temporary relief of symptoms caused by hay fever and allergies (runny nose, sneezing, itchy/watery eyes, scratchy nose or throat). It is available in a variety of forms, including tablets, oral disintegrating tablets, and syrup.
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