Lupus (Systemic Lupus Erythematosus)Medical Author:
William C. Shiel Jr., MD, FACP, FACR
William C. Shiel Jr., MD, FACP, FACRDr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology. Medical Editor:
Melissa Conrad Stöppler, MD, Chief Medical Editor
Melissa Conrad Stöppler, MD, Chief Medical EditorMelissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.
Does Stress Affect Lupus?Medical Author: William C. Shiel Jr., MD, FACP, FACR
For the purpose of this topic, I will define stress as human reactions to forces that tend to disturb our normal functional (physiologic) balance (equilibrium). Stress, in this general sense, refers to any adverse condition or state that affects our normal well-being. Such stress can be imposed on us by, for example, work, a spouse, other people, ourselves, or by setting our daily schedule too rigorously. Lupus OverviewSystemic lupus erythematosus (SLE), or lupus, is an autoimmune disease in which a person's immune system attacks various organs or cells of the body, causing damage and dysfunction. Lupus is called a multisystem disease because it can affect many different tissues and organs in the body. Some patients with lupus have very mild disease, which can be treated with simple medications, whereas others can have serious, life-threatening complications. Lupus is more common in women than men, and for reasons that are not precisely understood, its peak incidence is after puberty. While lupus is a chronic illness, it is characterized by periods when the disease activity is minimal or absent (remission) and when it is active (relapse or flare). The outlook (prognosis) for patients with lupus today is much better than years ago because of greater awareness and more accurate tests leading to earlier diagnosis and treatment as well as more effective and safer medications and monitoring methods. Viewer Comments & ReviewsLupus - TreatmentsThe eMedicineHealth physician editors ask:What treatments have been effective for your lupus? Lupus - Symptoms at Onset of DiseaseThe eMedicineHealth physician editors asked:The symptoms of lupus can vary greatly from patient to patient. What were your symptoms at the onset of your disease? |
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Lupus (Systemic Lupus Erythematosus)
Lupus (Systemic Lupus Erythematosus) »
Topic Overview
What is systemic lupus erythematosus, or lupus?
Lupus is an autoimmune disease, which means that the body's natural defense system (immune system) attacks its own tissues instead of attacking foreign substances like bacteria and viruses. This causes inflammation. Inflammation causes swelling, pain, and tissue damage throughout the body. If you develop severe lupus, you may have problems with your kidneys, heart, lungs, nervous system, or blood cells. Lupus is the common name for systemic lupus erythematosus, also called SLE.
Although some people with lupus have only mild symptoms, the disease is lifelong and can become severe. But most people can control their symptoms and prevent severe damage to their organs. They do this by seeing their doctors often for checkups, getting enough rest and exercise, and taking medicines.
This topic focuses on systemic lupus erythematosus (SLE), the most common and most serious type of lupus. But there ar...
Read What Your Physician is Reading on Medscape
Systemic Lupus Erythematosus »
Systemic lupus erythematosus (SLE) is a chronic, multifaceted inflammatory disease that can affect every organ system of the body.
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Let's start by discussing what is meant by stress. Stress means different things to different people
based on their backgrounds and their current emotional and physical condition. For some people, milk
spilling on the table causes a major emotional reaction. To others, a tank rolling through the living
room might be viewed as just another life experience!

