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February 8, 2012
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Lymphoma (cont.)

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Lymphoma Symptoms and Signs

Often, the first sign of lymphoma is a painless swelling in the neck, under an arm, or in the groin.

  • Lymph nodes or tissues elsewhere in the body may also swell. The spleen, for example, often becomes enlarged in lymphoma.


  • The enlarged lymph node sometimes causes other symptoms by pressing against a vein or lymphatic vessel (swelling of an arm or leg), a nerve (pain, numbness, or tingling), or the stomach (early feeling of fullness).


  • Enlargement of the spleen may cause abdominal pain or discomfort.


  • Many people have no other symptoms.

Symptoms of lymphoma may include the following:

  • Fevers


  • Chills


  • Unexplained weight loss


  • Night sweats


  • Lack of energy


  • Itching (up to 25% of patients develop this itch, most commonly in the lower extremity but it can occur anywhere, be local, or spreading over the whole body)

These symptoms are nonspecific. This means that they could be caused by any number of conditions unrelated to cancer. For instance, they could be signs of the flu or other viral infection, but in those cases, they would not last very long. In lymphoma, the symptoms persist over time and cannot be explained by an infection or another disease.

Viewer Comments & Reviews

Lymphoma - Effective Treatment

The eMedicineHealth physician editors ask:

What treatment has been effective for your lymphoma?

Lymphoma - Symptoms at Onset of Disease

The eMedicineHealth physician editors asked:

Lymphoma symptoms can vary greatly from patient to patient. What were your symptoms at the onset of your disease?

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Read What Your Physician is Reading on Medscape

Lymphoma, B-Cell »

Non-Hodgkin lymphoma (NHL) is a heterogenous group of lymphoproliferative malignancies with differing patterns of behavior and responses to treatment (Armitage, 1993).

Read More on Medscape Reference »

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