miglitol, Glyset Glossary of Terms

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Abdominal: Relating to the abdomen, the belly, that part of the body that contains all of the structures between the chest and the pelvis. The abdomen is separated anatomically from the chest by the diaphragm, the powerful muscle spanning the body cavity below the lungs.
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Abdominal pain: Pain in the belly. Abdominal pain can be acute or chronic. It may reflect a major problem with one of the organs in the abdomen, such as appendicitis or a perforated intestine, or it may result from a fairly minor problem, such as excess buildup of intestinal gas.

Absorption: Uptake. For example, intestinal absorption is the uptake of food (or other substances) from the digestive tract.

Blood glucose: The main sugar that the body makes from the food in the diet. Glucose is carried through the bloodstream to provide energy to all cells in the body. Cells cannot use glucose without the help of insulin.
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Blood sugar: Blood glucose. See also: High blood sugar; Low blood sugar.

Bowel: The small and large intestine.

Carbohydrate: One of the three nutrient compounds, along with fat and protein, used as energy sources (calories) by the body. Carbohydrates take the form of simple sugars or of more complex forms, such as starches and fiber. Complex carbohydrates come naturally from plants. Intake of complex carbohydrates, when they are substituted for saturated fat, can lower blood cholesterol. Carbohydrates produce 4 calories of energy per gram. When eaten, all carbohydrates are broken down into the sugar glucose.

Carbohydrates: Mainly sugars and starches, together constituting one of the three principal types of nutrients used as energy sources (calories) by the body. Carbohydrates can also be defined chemically as neutral compounds of carbon, hydrogen and oxygen.
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Chronic: In medicine, lasting a long time. A chronic condition is one that lasts 3 months or more. Chronic diseases are in contrast to those that are acute (abrupt, sharp, and brief) or subacute (within the interval between acute and chronic).

Crohn's disease: A chronic inflammatory disease, primarily involving the small and large intestine, but which can affect other parts of the digestive system as well. It is named for Burrill Crohn, the American gastroenterologist who first described the disease in 1932.
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Dextrose: Glucose, a simple sugar.

Diabetes: Refers to diabetes mellitus or, less often, to diabetes insipidus. Diabetes mellitus and diabetes insipidus share the name "diabetes" because they are both conditions characterized by excessive urination (polyuria).
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Diarrhea: A common condition that involves unusually frequent and liquid bowel movements. The opposite of constipation. There are many infectious and noninfectious causes of diarrhea. Persistent diarrhea is both uncomfortable and dangerous to the health because it can indicate an underlying infection and may mean that the body is not able to absorb some nutrients due to a problem in the bowels. Treatment includes drinking plenty of fluids to prevent dehydration and taking over-the-counter remedies. People with diarrhea that persists for more than a couple days, particularly small children or elderly people, should seek medical attention.

Dysfunction: Difficult function or abnormal function.
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Enzymes: Proteins that act as a catalysts in mediating and speeding a specific chemical reaction.

Flatulence: Excess gas in the intestinal tract. But excess flatulence is difficult to define without a yardstick to measure the "normal" frequency of gas passages. Symptom-free individuals have recorded approximately 14 passages of gas per 24 hours. From the Latin flastus, meaning blowing, as a breeze or snort.

Generic: 1. The chemical name of a drug. 2. A term referring to the chemical makeup of a drug rather than to the advertised brand name under which the drug may be sold. 3.A term referring to any drug marketed under its chemical name without advertising.

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Glucose: The simple sugar that is the chief source of energy. Glucose is found in the blood and is the main sugar that the body manufactures. The body makes glucose from all three elements of food'protein, fats, and carbohydrates'but the largest amount of glucose derives from carbohydrates. Glucose serves as the major source of energy for living cells. However, cells cannot use glucose without the help of insulin. Also known as dextrose.

Hypoglycemia: Low blood sugar (glucose). Hypoglycemia may be associated with symptoms such as anxiety, sweating, tremor, palpitations, nausea, and pallor. Hypoglycemia also starves the brain of glucose energy, which is essential for proper brain function. Lack of glucose energy to the brain can cause symptoms ranging from headache, mild confusion, abnormal behavior, loss of consciousness, seizure, and coma. Severe hypoglycemia can cause death. The causes of hypoglycemia include use of drugs (such as insulin), liver disease, surgical absence of the stomach, tumors that release excess amounts of insulin, and pre-diabetes. In some patients, symptoms of hypoglycemia occur during fasting (fasting hypoglycemia). In others, symptoms of hypoglycemia occur after meals (reactive hypoglycemia). Immediate treatment of severe hypoglycemia consists of administering large amounts of glucose and repeating this treatment at intervals if the symptoms persist. Treatment must also be directed at the underlying cause. Treatment of reactive hypoglycemia involves changing the diet, including eating fewer concentrated sweets and ingesting multiple small meals throughout the day.

Infant: A young baby, from birth to 12 months of age.

Inflammatory bowel disease: A group of chronic intestinal diseases characterized by inflammation of the bowel -- the large or small intestine. The most common types of inflammatory bowel disease (IBD) are ulcerative colitis and Crohn disease.
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Insulin: A natural hormone made by the pancreas that controls the level of the sugar glucose in the blood. Insulin permits cells to use glucose for energy. Cells cannot utilize glucose without insulin.
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Intestinal obstruction: Blockage of the intestine by infolding (intussusception), malformation, tumor, digestive problems, a foreign body, or inflammation. Symptoms can include crampy abdominal pain, lack of ability to eliminate normal feces, and eventually shock. On examining the abdomen, the doctor may feel a mass. Abdominal X-rays may suggest intestinal obstruction, but a barium enema may be needed to show the actual cause. Treatment depends on the cause of the obstruction. See also: Intussusception.

Intestine: The long, tubelike organ in the abdomen that completes the process of digestion. It consists of the small and large intestines.

Iron: An essential mineral. Iron is necessary for the transport of oxygen (via hemoglobin in red blood cells) and for oxidation by cells (via cytochrome). Deficiency of iron is a common cause of anemia. Food sources of iron include meat, poultry, eggs, vegetables and cereals (especially those fortified with iron). According to the National Academy of Sciences, the Recommended Dietary Allowances of iron are 15 milligrams per day for women and 10 milligrams per day for men. Iron overload can damage the heart, liver, gonads and other organs. Iron overload is a particular risk in people who may have certain genetic conditions (hemochromatosis) sometimes without knowing it and also in people receiving recurrent blood transfusions. Iron supplements meant for adults (such as pregnant women) are a major cause of poisoning in children.

Kidney: One of a pair of organs located in the right and left side of the abdomen. The kidneys remove waste products from the blood and produce urine. As blood flows through the kidneys, the kidneys filter waste products, chemicals, and unneeded water from the blood. Urine collects in the middle of each kidney, in an area called the renal pelvis. It then drains from the kidney through a long tube, the ureter, to the bladder, where it is stored until elimination. The kidneys also make substances that help control blood pressure and regulate the formation of red blood cells.

Nerve: A bundle of fibers that uses electrical and chemical signals to transmit sensory and motor information from one body part to another. The fibrous portions of a nerve are covered by a sheath called myelin and/or a membrane called neurilemma. (Note that entries for specific nerves can be found under the names of the particular nerves. For example, the optic nerve is not under 'nerve, optic' but rather under 'optic nerve.')

Nursing: 1) Profession concerned with the provision of services essential to the maintenance and restoration of health by attending the needs of sick persons. 2) Feeding a infant at the breast.

Obstruction: Blockage of a passageway. See, for example: Airway obstruction; Intestinal obstruction.

Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia. Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Pancreas: A spongy, tube-shaped organ that is about 6 inches long and is located in the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen. It is connected to the upper end of the small intestine. The narrow end of the pancreas, called the tail, extends to the left side of the body. The pancreas makes pancreatic juices and hormones, including insulin and secretin. Pancreatic juices contain enzymes that help digest food in the small intestine. Both pancreatic enzymes and hormones are needed to keep the body working correctly. As pancreatic juices are made, they flow into the main pancreatic duct, which joins to the common bile duct, which connects the pancreas to the liver and the gallbladder and carries bile to the small intestine near the stomach. The pancreas is thus a compound gland in the sense that it is composed of both exocrine and endocrine tissues. The exocrine function of the pancreas involves the synthesis and secretion of pancreatic juices. The endocrine function resides in the million or so cellular islands (the islets of Langerhans) that are embedded between the exocrine units of the pancreas. Beta cells of the islets of Langerhans secrete insulin, which helps control carbohydrate metabolism. Alpha cells of the islets of Langerhans secrete glucagon, which counters the action of insulin.

Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.

Rash: Breaking out (eruption) of the skin. A rash can be caused by an underlying medical condition, hormonal cycles, allergies, or contact with irritating substances. Treatment depends on the underlying cause of the rash. Medically, a rash is referred to as an exanthem.

Serum: The clear liquid that can be separated from clotted blood. Serum differs from plasma, the liquid portion of normal unclotted blood containing the red and white cells and platelets. It is the clot that makes the difference between serum and plasma.
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Small intestine: The part of the digestive tract that extends from the stomach to the large intestine.

Sulfonylurea: A class of oral hypoglycemic agents (medications that lower the level of blood glucose) taken by people with type 2 diabetes. The sulfonylureas increase the secretion of insulin by the pancreas. There are two generations of sulfonylureas. The main difference between the first- and second-generation sulfonylureas is in the way they are 'eliminated from the body. As a consequence, second-generation sulfonylureas are usually taken less 'frequently each day than first-generation sulfonylureas and generally are preferred when there is poor function of the kidneys. Examples of first-'generation sulfonylureas are chlorpropamide (Diabinese) and tolbutamide (Orinase). The second-generation sulfonylureas include glipizide (Glucotrol and Glucotrol XL), glyburide (Diabeta, Micronase, and Glynase PresTab), and glimepiride (Amaryl). These drugs are effective in rapidly 'lowering blood sugar but run the risk of causing hypoglycemia.

Therapy: The treatment of disease. Therapy is synonymous with treatment.