Migraine Headache in Children Glossary of Medical Terms

Abdominal: Relating to the abdomen, the belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
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Abdominal pain: Pain in the belly (the abdomen). Abdominal pain can come from conditions affecting a variety of organs. The abdomen is an anatomical area that is bounded by the lower margin of the ribs above, the pelvic bone (pubic ramus) below, and the flanks on each side. Although abdominal pain can arise from the tissues of the abdominal wall that surround the abdominal cavity (the skin and abdominal wall muscles), the term abdominal pain generally is used to describe pain originating from organs within the abdominal cavity (from beneath the skin and muscles). These organs include the stomach, small intestine, colon, liver, gallbladder, and pancreas.
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Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Abortive: The word "abortive" has a number of meanings including prematurely born; fruitless or unsuccessful; imperfectly formed or developed; tending to cut short.
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Absorption: Uptake. In the biomedical sciences, absorption has diverse specific meanings.
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Acetaminophen: A pain reliever and fever reducer. Brand name: Tylenol. The exact mechanism of action of acetaminophen is not known. Acetaminophen relieves pain by elevating the pain threshold (that is, by requiring a greater amount of pain to develop before it is felt by a person). Acetaminophen reduces fever through its action on the heat-regulating center (the "thermostat") of the brain. Generic is available.
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Acupuncture: The practice of inserting needles into the body to reduce pain or induce anesthesia . More broadly, acupuncture is a family of procedures involving the stimulation of anatomical locations on or in the skin by a variety of techniques. There are a number of different approaches to diagnosis and treatment in American acupuncture that incorporate medical traditions from China, Japan, Korea, and other countries. The most thoroughly studied mechanism of stimulation of acupuncture points employs penetration of the skin by thin, solid, metallic needles, which are manipulated manually or by electrical stimulation.
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Acute: Of abrupt onset, in reference to a disease. Acute often also connotes an illness that is of short duration, rapidly progressive, and in need of urgent care.
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Aleve: See: Naproxen .
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Alice in Wonderland syndrome: A syndrome of distorted space, time and body image. The patient with the Alice in Wonderland syndrome has a feeling that their entire body or parts of it have been altered in shape and size. The syndrome is usually associated with visual hallucinations. The majority of patients with the syndrome have a family history of migraine headache or have overt migraine themselves.
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Amitriptyline: An antidepressant medication. In some patients with depression , abnormal levels of brain chemicals called neurotransmitters may relate to the depression. Amitriptyline elevates mood by raising the level of neurotransmitters in brain tissue. Amitriptyline is also a sedative that is useful for depressed patients with insomnia, restlessness, and nervousness. It is sometimes used to treat fibromyalgia and symptoms related to chronic pain . Brand names are Elavil and Endep. A generic version is available.
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Amnesia: Lack of memory . Amnesia after trauma can be antegrade or retrograde, depending upon whether the lack of memory relates to events occurring after or before the trauma. Amnesia is as compared to hypermnesia and hypomnesia . From a- + the Greek mneme, memory.
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Analgesic: A drug or medicine given to reduce pain without resulting in loss of consciousness. Analgesics are sometimes referred to as painkiller medications. There are many different types of analgesic medications available in both prescription and over-the-counter preparations. Examples of analgesic drugs include aspirin , acetaminophen (Tylenol), ibuprofen (Motrin, Advil), naproxen (Aleve, Naprosyn), the COX-2 inhibitor celecoxib , and narcotic drugs including morphine, oxycodone , and hydrocodone (Vicodin). Analgesics may also be combined with other drugs in some types of medications (for example, analgesics are combined with decongestants and/or antihistamine in many over-the-counter cold remedies).
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Anaprox: See: Naproxen .
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Anorexia: An eating disorder characterized by markedly reduced appetite or total aversion to food. Anorexia is a serious psychological disorder. It is a condition that goes well beyond out-of-control dieting. The person with anorexia, most often a girl or young woman, initially begins dieting to lose weight. Over time, the weight loss becomes a sign of mastery and control. The drive to become thinner is thought to be secondary to concerns about control and fears relating to one's body. The individual continues the endless cycle of restrictive eating, often to a point close to starvation. This becomes an obsession and is similar to an addiction to a drug. Anorexia can be life-threatening. Also called anorexia nervosa .
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Antidepressants : Anything, and especially a drug, used to prevent or treat depression .
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Anxiety: A feeling of apprehension and fear characterized by physical symptoms such as palpitations , sweating, and feelings of stress . Anxiety disorders are serious medical illnesses that affect approximately 19 million American adults. These disorders fill people's lives with overwhelming anxiety and fear. Unlike the relatively mild, brief anxiety caused by a stressful event such as a business presentation or a first date, anxiety disorders are chronic, relentless, and can grow progressively worse if not treated.
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Aphasia: One in a group of speech disorders in which there is a defect or loss of the power of expression by speech, writing, or signs, or a defect or loss of the power of comprehension of spoken or written language. See, for example, auditory aphasia .
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Artery: A vessel that carries blood high in oxygen content away from the heart to the farthest reaches of the body. Since blood in arteries is usually full of oxygen, the hemoglobin in the red blood cells is oxygenated. The resultant form of hemoglobin (oxyhemoglobin) is what makes arterial blood look bright red.
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Aspirin: A good example of a tradename that entered into the language, Aspirin was once the Bayer trademark for acetylsalicylic acid .
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Asthma : A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways. Asthma involves only the bronchial tubes and does not affect the air sacs ( alveoli ) or the lung tissue (the parenchyma of the lung) itself.
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Ataxia: Wobbliness. Incoordination and unsteadiness due to the brain's failure to regulate the body's posture and regulate the strength and direction of limb movements. Ataxia is usually a consequence of disease in the brain, specifically in the cerebellum which lies beneath the back part of the cerebrum.
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Atonic: Without normal muscle tone or strength. An atonic seizure is one in which the person suddenly loses muscle tone and strength and cannot sit or stand upright and, unless supported, falls down.
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Aura: A premonition. There is often an aura before a migraine or a grand mal seizure. The aura, a symptom of brain malfunction, may consist of flashing lights, a gleam of light, blurred vision, an odor, the feeling of a breeze, numbness, weakness, or difficulty speaking.
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Basilar: Located at or near the base of a structure, especially the base of the skull.
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Benign: Not cancer. Not malignant . A benign tumor does not invade surrounding tissue or spread to other parts of the body. A benign tumor may grow but it stays put (in the same place).
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Bilateral: Having, or relating to, two sides. Bilateral is as opposed, for example, to unilateral (which means having, or relating to, one side).
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Biofeedback: A method of treatment that uses monitors to feed back to patients physiological information of which they are normally unaware. By watching the monitor, patients can learn by trial and error to adjust their thinking and other mental processes in order to control "involuntary" bodily processes such as blood pressure, temperature, gastrointestinal functioning, and brain wave activity.
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Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle . It's measurement is recorded by two numbers. The first ( systolic pressure) is measured after the heart contracts and is highest. The second ( diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called " hypertension ".
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Blurred vision: Lack of sharpness of vision with, as a result, the inability to see fine detail. Blurred vision can occur when a person who wears corrective lens is without them. Blurred vision can also be an important clue to eye disease.
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Brain: That part of the central nervous system that is located within the cranium ( skull ). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."
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Brain tumor : A benign or malignant growth in the brain. Primary brain tumors arise in brain tissue. Secondary brain tumors are cancers that have spread to the brain tissue (metastasized) from elsewhere in the body. Brain tumors can and do occur at any age.
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Caffeine: A stimulant found naturally in coffee beans, tea leaves, cocoa beans (chocolate) and kola nuts (cola) and added to soft drinks, foods, and medicines. A cup of coffee has 100-250 milligrams of caffeine. Black tea brewed for 4 minutes has 40-100 milligrams. Green tea has one-third as much caffeine as black tea.
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Calcium: A mineral found mainly in the hard part of bones, where it is stored. Calcium is added to bones by cells called osteoblasts and is removed from bones by cells called osteoclasts. Calcium is essential for healthy bones. It is also important for muscle contraction, heart action, nervous system maintenance, and normal blood clotting. Food sources of calcium include dairy foods, some leafy green vegetables such as broccoli and collards, canned salmon, clams, oysters, calcium-fortified foods, and tofu. According to the National Academy of Sciences, adequate intake of calcium is 1,200 milligrams a day (four glasses of milk) for men and women 51 and older, 1,000 milligrams a day for adults 19 through 50, and 1,300 milligrams a day for children 9 through 18. The upper limit for calcium intake is 2.5 grams daily. Learn more about Calcium with evidence-based information on RxList.

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Cardiovascular: The circulatory system comprising the heart and blood vessels which carries nutrients and oxygen to the tissues of the body and removes carbon dioxide and other wastes from them.
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Cerebellar: Pertaining to the cerebellum , the part of the brain in the back of the head between the cerebrum and the brain stem . The cerebellum controls balance for walking and standing and other complex motor functions.
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Cerebellum: The portion of the brain in the back of the head between the cerebrum and the brain stem. The cerebellum controls balance for walking and standing and other complex motor functions.
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Chills: feelings of coldness accompanied by shivering. Chills may develop after exposure to a cold environment or may accompany a fever .
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Circulation: The movement of fluid in a regular or circuitous course. Although the noun "circulation" does not necessarily refer to the circulation of the blood, for all practical purposes today it does. Heart failure is an example of a problem with the circulation.
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Cluster: In epidemiology, an aggregation of cases of a disease or another health-related condition, such as a cancer or birth defect, closely grouped in time and place. The number of cases in the cluster may or may not exceed the expected number. This is determined by cluster analysis, a set of statistical methods used to analyze clusters.
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Cognitive: Pertaining to cognition , the process of knowing and, more precisely, the process of being aware, knowing, thinking, learning and judging. The study of cognition touches on the fields of psychology , linguistics, computer science, neuroscience , mathematics, ethology and philosophy.
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Coma: A state of deep unarousable unconsciousness.
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Common migraine: Migraine without aura . The most frequent type, accounting for about 80-85% of migraine. See: Migraine .
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Concussion: A traumatic injury to tissues of the body such as the brain as a result of a violent blow, shaking, or spinning.
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Constipation: Infrequent (and frequently incomplete) bowel movements. The opposite of diarrhea , constipation is commonly caused by irritable bowel syndrome, diverticulosis , and medications (constipation can paradoxically be caused by overuse of laxatives). Colon cancer can narrow the colon and thereby cause constipation. The large bowel (colon) can be visualized by barium enema x-rays, sigmoidoscopy, and colonoscopy. Barring a condition such as cancer, high-fiber diets can frequently relieve the constipation.
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Consultant: An individual to whom one refers for expert advice or services. The use of consultants is common in medicine.
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Contraction: The tightening and shortening of a muscle.
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Cranial: 1. Pertaining to the cranium or skull. 2. Toward the head. As opposed to caudad. The eye is cranial to the jaw. For a more complete listing of terms used in medicine for spatial orientation, please see the entry to " Anatomic Orientation Terms ".
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Cutaneous: Relating to the skin. As, for example, in cutaneous allodynia , a cutaneous papilloma , and cutaneous syndactyly . From the Latin cutis meaning skin.
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Cyclic vomiting syndrome: A syndrome characterized by episodes, bouts, or cycles of severe nausea and vomiting that last for hours or even days and alternate with longer asymptomatic periods (with no symptoms). The cause of the syndrome is unknown. Each episode is similar to previous ones and tends to start at about the same time of day, last the same length of time, and present the same symptoms at the same level of intensity. Episodes of CVS can be so severe that a person may have to stay in bed for days, unable to go to school or work. Because other common diseases and disorders can also cause cycles of vomiting, people with the syndrome may initially be misdiagnosed.
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Deafness: Deafness is defined by partial or complete hearing loss. Levels of hearing impairment vary from a mild but important loss of sensitivity to a total loss of hearing. Older adults suffer most often from hearing loss. Age-related hearing loss affects 30 to 35 percent of the population between the ages of 65 and 75 years, and 40 percent of the population over the age of 75. The most common cause of hearing loss in children is otitis media, a disorder that affects predominantly infants and young children. A substantial number of hearing impairments are caused by environmental factors such as noise, drugs, and toxins. Many sensorineural hearing losses result from a genetic predisposition.
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Dehydration : Excessive loss of body water. Diseases of the gastrointestinal tract that cause vomiting or diarrhea may, for example, lead to dehydration. There are a number of other causes of dehydration including heat exposure, prolonged vigorous exercise (e.g., in a marathon), kidney disease, and medications (diuretics).
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Depression : An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Diarrhea : A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation . The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
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Diplopia: The condition in which a single object appears as two objects. Also called "double vision." From the Greek diplo- (double) + -opia (vision). See also: Diplopia, binocular ; Diplopia, monocular .
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Dizziness: Painless head discomfort with many possible causes including disturbances of vision, the brain, balance (vestibular) system of the inner ear, and gastrointestinal system. Dizziness is a medically indistinct term which laypersons use to describe a variety of conditions ranging from lightheadedness, unsteadiness to vertigo .
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Dysarthria: Speech that is characteristically slurred, slow, and difficult to produce (difficult to understand). The person with dysarthria may also have problems controlling the pitch, loudness, rhythm, and voice qualities of their speech.
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Dysphasia: One in a group of speech disorders in which there is impairment of the power of expression by speech, writing, or signs, or impairment of the power of comprehension of spoken or written language. More severe forms of dysphasia are called aphasia .
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Elavil: See: Amitriptyline .
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Emergency department: The department of a hospital responsible for the provision of medical and surgical care to patients arriving at the hospital in need of immediate care. Emergency department personnel may also respond to certain situations within the hospital such cardiac arrests.
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Encephalitis: Inflammation of the brain. Encephalitis occurs, for example, in 1 in 1,000 cases of measles . It may start (up to 3 weeks) after onset of the measles rash and present with high fever , convulsions, and coma. It usually runs a blessedly short course with full recovery within a week. Or it may eventuate in central nervous system impairment or death.
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Endoscopy: Endoscopy is a broad term used to described examining the inside of the body using a lighted, flexible instrument called an endoscope. In general, an endoscope is introduced into the body through a natural opening like the mouth or anus. Although endoscopy can include examination of other organs, the most common endoscopic procedures evaluate the esophagus (swallowing tube), stomach, and portions of the intestine.
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Epilepsy (seizure disorder): When nerve cells in the brain fire electrical impulses at a rate of up to four times higher than normal, this causes a sort of electrical storm in the brain, known as a seizure. A pattern of repeated seizures is referred to as epilepsy . Known causes include head injuries, brain tumors, lead poisoning, maldevelopment of the brain, genetic and infectious illnesses. But in fully half of cases, no cause can be found. Medication controls seizures for the majority of patients.
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Estrogen: Estrogen is a female hormone produced by the ovaries. Estrogen deficiency can lead to osteoporosis .
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Familial: A condition that is tends to occur more often in family members than expected by chance alone. A familial disease may be genetic (such as cystic fibrosis ) or environmental (such as tuberculosis ).
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Family history: The family structure and relationships within the family, including information about diseases in family members.
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Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.
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Fever : Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
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Flu: Short for influenza . The flu is caused by viruses that infect the respiratory tract which are divided into three types, designated A, B, and C. Most people who get the flu recover completely in 1 to 2 weeks, but some people develop serious and potentially life-threatening medical complications, such as pneumonia . Much of the illness and death caused by influenza can be prevented by annual influenza vaccination.
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Gene: The basic biological unit of heredity . A segment of deoxyribonucleic acid (DNA) needed to contribute to a function.
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Glutamate: A form of glutamic acid. See: Glutamic acid .
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Head injury: Damage to any of the structures of the head as a result of trauma. While the term "head injury" is most often used to refer to an injury to the brain, head injuries may also involve the bones, muscles, blood vessels, skin, and other organs of the face or head. A head injury does not always mean that there is an associated brain injury. Most head injuries are caused by blows to the head from numerous causes including motor vehicle accidents and falls. Head injuries are one of the most common causes of death and disability in the United States.
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Headache : A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
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Hemiparesis: Weakness on one side of the body.
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Hemiplegia: Paralysis of one side of the body. From hemi- (half) + plege (a blow, stroke ).
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Hemiplegic: Pertaining to hemiplegia ( paralysis of one side of the body.)
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Hemorrhage: Bleeding or the abnormal flow of blood.
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High altitude: Altitude sickness occurs at high altitude. So what is high altitude?
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High blood pressure : Also known as hypertension, high blood pressure is, by definition, a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
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Histamine: Substance that plays a major role in many allergic reactions. Histamine dilates blood vessels and makes the vessel walls abnormally permeable.
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Horizontal: In anatomy, a plane passing through the standing body. A person lying on a bed is considered in a horizontal position.
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Ibuprofen: A non-steroidal anti-inflammatory drug (NSAID) commonly used to treat pain, swelling, and fever . Common brand names for Ibuprofen include Advil, Motrin, and Nuprin.
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Illusion: A perception that occurs when a sensory stimulus is present but is incorrectly perceived and misinterpreted, such as hearing the wind as someone crying. Everyone may occasionally experience an illusion. However, illusions are extraordinarily common in people suffering from schizophrenia .
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Imitrex: Brand name for sumatriptan , a triptan drug for the treatment of migraine .
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Indicate: In medicine, to make a treatment or procedure advisable because of a particular condition or circumstance. For example, certain medications are indicated for the treatment of hypertension during pregnancy while others are contraindicated .
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Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response .
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Injury: Harm or hurt. The term "injury" may be applied in medicine to damage inflicted upon oneself as in a hamstring injury or by an external agent on as in a cold injury . The injury may be accidental or deliberate, as with a needlestick injury . The term "injury" may be synonymous (depending on the context) with a wound or with trauma .
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JAMA: The Journal of the American Medical Association. JAMA began publication in 1883. It now bills itself as "the world's best-read medical journal". However one defines "best-read", JAMA clearly ranks as one of the two leading general medical journals published in the United States. (The other is the New England Journal of Medicine.)
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Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."
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Lethargy: 1. Abnormal drowsiness, stupor. 2. A state of indifference.
From the Greek lethargia, drowsiness.
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Lumbar: Referring to the 5 lumbar vertebrae which are situated below the thoracic vertebrae and above the sacral vertebrae in the spinal column. The 5 lumbar vertebrae are represented by the symbols L1 through L5. There are correspondingly 5 lumbar nerves.
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Lumbar puncture: A lumbar puncture or "LP" is a procedure whereby spinal fluid is removed from the spinal canal for the purpose of diagnostic testing. It is particularly helpful in the diagnosis of inflammatory diseases of the central nervous system, especially infections, such as meningitis. It can also provide clues to the diagnosis of stroke , spinal cord tumor and cancer in the central nervous system.
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Macrocephaly: An abnormally large head. The opposite of macrocephaly is microcephaly (an abnormally small head).
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Marker: A piece of DNA that lies on a chromosome so close to a gene that the marker and the gene are inherited together. A marker is thus an identifiable heritable spot on a chromosome. A marker can be an expressed region of DNA (a gene) or a segment of DNA with no known coding function. All that matters is that the marker can be detected and trailed.
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Medical history: 1. In clinical medicine, the patient's past and present which may contain clues bearing on their health past, present, and future. The medical history, being an account of all medical events and problems a person has experienced, including psychiatric illness, is especially helpful when a differential diagnosis is needed.
2. The history of medicine.
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Membrane: A very thin layer of tissue that covers a surface.
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Memory: 1. The ability to recover information about past events or knowledge. 2. The process of recovering information about past events or knowledge. 3. Cognitive reconstruction. The brain engages in a remarkable reshuffling process in an attempt to extract what is general and what is particular about each passing moment.
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Menarche: The time in a girl's life that menstruation first begins. During the menarche period, menstruation may be irregular and unpredictable. Mood, weight, activity level, and growth rate may fluctuate with the hormone levels as well. Synonymous with female puberty.
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Meninges: The three membranes that cover the brain and spinal cord (singular: meninx).
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Meningitis: Inflammation of the meninges, usually due to a bacterial infection but sometimes from viral, protozoan, or other causes (in some cases the cause cannot be determined).
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Menstrual: Pertaining to menstruation (the menses), as in last menstrual period , menstrual cramps , menstrual cycle , and premenstrual syndrome . From the Latin menstrualis, from mensis meaning month.
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Menstrual cycle: The monthly cycle of changes in the ovaries and the lining of the uterus (endometrium), starting with the preparation of an egg for fertilization. When the follicle of the prepared egg in the ovary breaks, it is released for fertilization and ovulation occurs. Unless pregnancy occurs, the cycle ends with the shedding of part of the endometrium, which is menstruation. Although it is actually the end of the physical cycle, the first day of menstrual bleeding is designated as "day 1" of the menstrual cycle in medical parlance.
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Menstrual migraine: A migraine headache that affects a woman each month between the 2nd day before the start of the menstrual period and the end of menstruation. Menstrual migraine is different from nonmenstrual attacks of migraine, even in the same women, in the regularity of its timing and its greater severity. Compared with other times in the menstrual cycle, a migraine is more than twice as likely to occur during the first 3 days of menstruation and more than three times as likely to be severe.
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Menstruation: The periodic blood that flows as a discharge from the uterus. Also called menorrhea, the time during which menstruation occurs is referred to as menses. The menses occurs at approximately 4 week intervals to compose the menstrual cycle.
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Migraine: Usually, periodic attacks of headaches on one or both sides of the head. These may be accompanied by nausea, vomiting, increased sensitivity of the eyes to light (photophobia), increased sensitivity to sound (phonophobia), dizziness , blurred vision, cognitive disturbances, and other symptoms. Some migraines do not include headache, and migraines may or may not be preceded by an aura.
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Migraine aura: Sensory phenomena that may occur before a migraine. Visual auras may include flashing lights, geometric patterns, or distorted vision. Some people may have aural auras involving hearing sounds (usually buzzing), olfactory auras involving smelling odors not actually present, or tactile auras that present as a premonitory physical sensation. Auras are caused by unusual activity in the brain. The auras experienced by migraine sufferers are very similar to those associated with epilepsy .
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Migraine headache: The most common type of vascular headache involving abnormal sensitivity of arteries in the brain to various triggers resulting in rapid changes in the artery size due to spasm (constriction). Other arteries in the brain and scalp then open (dilate), and throbbing pain is perceived in the head. The tendency to migraine is inherited and appears to involve serotonin, a chemical in the brain involved in the transmission of nerve impulses that trigger the release of substances in the blood vessels that in turn cause the pain of the migraine. These nerve impulses cause the flashing lights and other sensory phenomena known as an aura that may accompany a migraine . Not all severe headaches are migraines and not all migraines are severe.
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Migraine without aura: See: Common migraine .
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Migraineur: A person who has migraine headache . Borrowed from the French.
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Molecule: The smallest unit of a substance that can exist alone and retain the character of that substance.
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Mono: Popular name for infectious mononucleosis .
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Monosodium glutamate: MSG, a sodium salt of the amino acid glutamic acid that enhances the flavor of certain foods. Originally isolated from seaweed, MSG is now made by fermenting corn, potatoes and rice. It does not enhance the four basic tastes (bitter, salty, sour, sweet) but it does enhance the complex flavors of meat, poultry, seafood, and vegetables. MSG is an important ingredient in the cuisines of China and Japan and is used commercially worldwide in many types of foods. It is naturally present at high levels in tomatoes and Parmesan cheese. In China, MSG is known as wei jing, which means flavor essence.
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Motion sickness: Motion sickness is a very common disturbance of the inner ear that is caused by repeated motion such as from the swell of the sea, the movement of a car, the motion of a plane in turbulent air, etc. In the inner ear (which is also called the labyrinth), motion sickness affects the sense of balance and equilibrium and, hence, the sense of spatial orientation.
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Motor: In medicine, having to do with the movement of a part of the body. Something that produces motion or refers to motion. For example, a motor neuron is a nerve cell that conveys an impulse to a muscle causing it to contract. The term "motor" today is also applied to a nerve that signals a gland to secrete. Motor is as opposed to sensory.
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Mucous: Pertaining to mucus, a thick fluid produced by the lining of some tissues of the body.
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Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
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Naprelan: See: Naproxen .
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Naprosyn: See: Naproxen .
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Naproxen : A non-steroidal anti-inflammatory drug (NSAID) used for the management of mild to moderate pain, fever, and inflammation . Naproxen blocks the enzyme cyclooxygenase that makes prostaglandins, resulting in lower concentrations of prostaglandins. As a consequence, inflammation, pain and fever are reduced. Brand names for naproxen include Anaprox, Naprelan, Naprosyn, and Aleve.
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Nasal: Having to do with the nose. Nasal drops are intended for the nose, not (for example) the eyes. The word "nasal" came from the Latin "nasus" meaning the nose or snout.
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Nausea: Nausea, is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza , medications, pain, and inner ear disease. When nausea and/or vomiting are persistent, or when they are accompanied by other severe symptoms such as abdominal pain , jaundice , fever, or bleeding, a physician should be consulted.
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Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.
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Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system .
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Neurological: Having to do with the nerves or the nervous system.
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Neurologist: A doctor who specializes in the diagnosis and treatment of disorders of the nervous system.
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Neurology: The medical specialty concerned with the diagnosis and treatment of disorders of the nervous system -- the brain, the spinal cord, and the nerves.
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Neuromuscular: Pertaining to both nerves and muscles, as in neuromuscular blockade by an anesthetic agent, the neuromuscular junction (the meeting place of a nerve and a muscle fiber), and neuromuscular transmission (the transfer of "information" from the nerve to the muscle).

NIH: The National Institutes of Health. The NIH is an important U.S. health agency. It is devoted to medical research. Administratively under the Department of Health and Human Services (HHS), the NIH consists of 20-some separate Institutes and Centers. NIH's program activities are represented by these Institutes and Centers.
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NINDS: Stands for the National Institute of Neurological Disorders and Stroke, one of the National Institutes of Health in the U.S., whose mission is to "support and conduct research and research training on the normal structure and function of the nervous system and on the causes, prevention, diagnosis, and treatment of more than 600 nervous system disorders including stroke , epilepsy , multiple sclerosis , Parkinson's disease, head and spinal cord injury, Alzheimer's disease, and brain tumors."
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Nuchal: Referring to the back of the neck (nape). For example, nuchal rigidity is a stiff neck, sometimes a symptom of meningitis.
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Nystagmus: Rapid rhythmic repetitious involuntary (unwilled) eye movements. Nystagmus can be horizontal, vertical or rotary.
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Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis . There is always an onset to a disease but never to the return to good health. The default setting is good health.
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Ophthalmic: Pertaining to the eye. An ophthalmic ointment is designed for the eye.
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Papilledema: Swelling of the head of the optic nerve, a sign of increased intracranial pressure. The optic nerve head, also called the optic disk or papilla, is the area where the optic nerve (the nerve that carries messages from the eye to the brain) enters the eyeball.
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Paralysis: Loss of voluntary movement (motor function). Paralysis that affects only one muscle or limb is partial paralysis, also known as palsy; paralysis of all muscles is total paralysis, as may occur in cases of botulism .
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Paresthesia: An abnormal sensation of the skin, such as numbness, tingling, pricking, burning, or creeping on the skin that has no objective cause. Paresthesia is the usual American spelling and paraesthesia the preferred English spelling.
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Pediatric: Pertaining to children.
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Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.
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Phenol: 1. A poisonous corrosive compound obtained by the distillation of coal tar that, in dilute solution, is an antimicrobial agent. Also called carbolic acid. 2. A generic term for any compound similar in structure to phenol (an organic compound with one or more hydroxyl groups attached to an aromatic or carbon ring).
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Phenothiazine: One of a group of tranquilizing drugs with antipsychotic actions thought to act by blocking dopaminergic transmission (messages sent using the substance dopamine) within the brain.
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Photophobia: Painful oversensitivity to light. For example, there is photophobia in measles (rubeola). Keeping the lights dim or the room darkened may be useful. Sunglasses may also help.
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Postural: Pertaining to the posture or position of the body, the attitude or carriage of the body as a whole, or the position of the limbs (the arms and legs). Postural hypotension is a drop in blood pressure ( hypotension ) due to a change in body position (a change in posture). It occurs when a person, often an older person, moves to a more vertical position: from sitting to standing or from lying down to sitting or standing. The change in posture causes a temporary reduction in blood flow and therefore a shortage of oxygen to the brain, which leads to lightheadedness and, sometimes, a "black out" episode, a loss of consciousness.
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Predispose: To make more likely or render susceptible. Smoking predisposes to a number of diseases, including esophageal cancer .
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Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.
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Prevalence: The proportion of individuals in a population having a disease. Prevalence is a statistical concept referring to the number of cases of a disease that are present in a particular population at a given time.
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Progesterone: A female hormone and the principal progestational hormone that is made mainly by the corpus luteum in the ovary and by the placenta. Progesterone prepares the lining (endometrium) of the uterus (the womb) to receive and sustain the fertilized egg and so permits pregnancy. Similarly refers to synthetic versions of the hormone. Also known as progestational hormone.
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Progressive: Increasing in scope or severity. Advancing. Going forward. In medicine, a disease that is progressive is going from bad to worse.
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Prophylactic: A preventive measure. The word comes from the Greek for "an advance guard," an apt term for a measure taken to fend off a disease or another unwanted consequence.
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Psychiatric: Pertaining to or within the purview of psychiatry , the medical specialty concerned with the prevention, diagnosis , and treatment of mental illness.
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Puberty: A complex biologic and psychologic process involving sexual development, accelerated growth, and adrenal maturation heralded by the secretion of gonadotropin releasing hormone (GnRH) from a part of the brain called the hypothalamus . This event is the first known step in the reproductive cascade. It initiates the pulsatile release of gonadotropins , gonadal secretion of sex steroids, pubertal development, and gametogenesis (the production of sperm and ova ).
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Pupil: The opening of the iris. The pupil may appear to open (dilate) and close (constrict) but it is really the iris that is the prime mover; the pupil is merely the absence of iris. The pupil determines how much light is let into the eye. Both pupils are usually of equal size. If they are not, that is termed anisocoria (from "a-", not + "iso", equal + "kore", pupil = not equal pupils).
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Quality of life: An important consideration in medical care, quality of life refers to the patient's ability to enjoy normal life activities. Some medical treatments can seriously impair quality of life without providing appreciable benefit, while others greatly enhance quality of life.
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Rebound: Return of the original symptoms when maneuvers or treatment is discontinued.
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Recurrent: Back again. A recurrent fever is a fever that has returned after an intermission: a recrudescent fever.
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Rehydration: The process of restoring lost water to the body tissues and fluids. Prompt rehydration is imperative whenever dehydration occurs, from diarrhea , exposure, lack of drinking water, or medication use. Rehydration can be by the oral route or by the intravenous administration of fluids.
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Relapse: The return of signs and symptoms of a disease after a patient has enjoyed a remission . For example, after treatment a patient with cancer of the colon went into remission with no sign or symptom of the tumor, remained in remission for 4 years, but then suffered a relapse and had to be treated once again for colon cancer.
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Remission: Disappearance of the signs and symptoms of cancer or other disease. When this happens, the disease is said to be "in remission." A remission can be temporary or permanent.
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Residual: Something left behind. With residual disease, the disease has not been eradicated.
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Retinal: Pertaining to the retina , the extraordinary layer of neurons (nerve cells) that line the back of the eye, which can sense light and create impulses capable of voyaging through the optic nerve to the brain where the impulses are recognized as an image.
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Rule out: A term much used in medicine, meaning to eliminate or exclude something from consideration. The ACB (albumin cobalt binding) test helps rule out a heart attack in the differential diagnosis of severe chest pain.
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Seizure: Uncontrolled electrical activity in the brain, which may produce a physical convulsion, minor physical signs, thought disturbances, or a combination of symptoms.
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Seizure disorders: One of a great many medical conditions that are characterized by episodes of uncontrolled electrical activity in the brain (seizures). Some seizure disorders are hereditary, but others are caused by birth defects or environmental hazards, such as lead poisoning. Seizure disorders are more likely to develop in patients who have other neurological disorders, psychiatric conditions, or immune-system problems. In some cases, uncontrolled seizures can cause brain damage, lowered intelligence, and permanent mental and physical impairment. Diagnosis is by observation, neurological examination, electroencephalogram (EEG), and in some cases more advanced brain imaging techniques. Treatment is usually by medication, although in difficult cases a special diet or brain surgery may be tried.
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Sensation: In medicine and physiology , sensation refers to the registration of an incoming ( afferent ) nerve impulse in that part of the brain called the sensorium , which is capable of such perception. Therefore, the awareness of a stimulus as a result of its perception by sensory receptors. (Sensory is here synonymous with sensation.)
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Sensitivity: 1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.
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Sensory: Relating to sensation , to the perception of a stimulus and the voyage made by incoming ( afferent ) nerve impulses from the sense organs to the nerve centers.
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Serotonin: A hormone , also called 5-hydroxytryptamine , in the pineal gland , blood platelets, the digestive tract, and the brain. Serotonin acts both as a chemical messenger that transmits nerve signals between nerve cells and that causes blood vessels to narrow.
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Sinus: 1. An air-filled cavity in a dense portion of a skull bone. The sinuses decrease the weight of the skull. The sinuses are formed in four right-left pairs. The frontal sinuses are positioned behind the forehead, while the maxillary sinuses are behind the cheeks. The sphenoid and ethmoid sinuses are deeper in the skull behind the eyes and maxillary sinuses. The sinuses are lined by mucous-secreting cells. Air enters the sinuses through small opening in bone called ostia. If an ostium is blocked, air cannot pass into the sinus and likewise mucous cannot drain out. See also: Sinusitis .
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Sinusitis: Sinusitis is inflammation of the lining membrane of any of the hollow areas (sinuses) of the bone of the skull around the nose. The sinuses are directly connected to the nasal cavities.
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Skull: The skull is a collection of bones which encase the brain and give form to the head and face. The bones of the skull include the following: the frontal, parietal, occipital, temporal, sphenoid, ethmoid, zygomatic, maxilla, nasal, vomer, palatine, inferior concha, and mandible.
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Sleep : The body's rest cycle.
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Sleepwalking : Purposeful moving, usually but not always including walking, while in a deep stage of sleep . Sleepwalking occurs most frequently in children, particularly boys. Sedatives tend to exacerbate rather than cure sleepwalking. The best measures are preventative: ensure that the sleepwalker is in a safe room for walking, and cannot accidentally fall through an open window or down stairs. Some types of sleepwalking are related to seizure disorders , bipolar disorder , or other neurological conditions, but most cases are transitory and due to unknown causes. Also called somnambulism.
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Sodium: The major positive ion (cation) in fluid outside of cells. The chemical notation for sodium is Na⁺. When combined with chloride, the resulting substance is table salt.
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Somnambulism: Sleepwalking. Purposeful moving, usually but not always including walking, while in a deep stage of sleep . Sleepwalking occurs most frequently in children, particularly boys. Sedatives tend to exacerbate rather than cure sleepwalking. The best measures are preventative: ensure that the sleepwalker is in a safe room for walking, and cannot accidentally fall through an open window or down stairs. Some types of sleepwalking are related to seizure disorders, bipolar disorders, or other neurological conditions, but most cases are transitory and due to unknown causes.
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Spasticity: A state of increased tone of a muscle (and an increase in the deep tendon reflexes). For example, with spasticity of the legs (spastic paraplegia) there is an increase in tone of the leg muscles so they feel tight and rigid and the knee jerk reflex is exaggerated.
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Spinal cord: The major column of nerve tissue that is connected to the brain and lies within the vertebral canal and from which the spinal nerves emerge. Thirty-one pairs of spinal nerves originate in the spinal cord: 8 cervical , 12 thoracic , 5 lumbar, 5 sacral, and 1 coccygeal. The spinal cord and the brain constitute the central nervous system ( CNS ). The spinal cord consists of nerve fibers that transmit impulses to and from the brain. Like the brain, the spinal cord is covered by three connective-tissue envelopes called the meninges . The space between the outer and middle envelopes is filled with cerebrospinal fluid ( CSF ), a clear colorless fluid that cushions the spinal cord against jarring shock. Also known simply as the cord.
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Spinal tap: Also known as a lumbar puncture or "LP", a spinal tap is a procedure whereby spinal fluid is removed from the spinal canal for the purpose of diagnostic testing. It is particularly helpful in the diagnosis of inflammatory diseases of the central nervous system, especially infections, such as meningitis. It can also provide clues to the diagnosis of stroke , spinal cord tumor and cancer in the central nervous system.
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Stage: As regards cancer , the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging .
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Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine.
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Stress: Forces from the outside world impinging on the individual. Stress is a normal part of life that can help us learn and grow. Conversely, stress can cause us significant problems.
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Stroke: The sudden death of some brain cells due to a lack of oxygen when the blood flow to the brain is impaired by blockage or rupture of an artery to the brain. A stroke is also called a cerebrovascular accident or, for short, a CVA.
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Subarachnoid: Literally, beneath the arachnoid, the middle of three membranes that cover the central nervous system. In practice, subarachnoid usually refers to the space between the arachnoid and the pia mater, the innermost membrane surrounding the central nervous system.
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Subarachnoid hemorrhage: Bleeding within the head into the space between two membranes that surround the brain. The bleeding is beneath the arachnoid membrane and just above the pia mater. (The arachnoid is the middle of three membranes around the brain while the pia mater is the innermost one.)
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Substance: 1. Material with particular features, as a pressor substance .
2. The material that makes up an organ or structure. Also known in medicine as the substantia.
3. A psychoactive drug as, for example, in substance abuse .
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Sumatriptan: A triptan drug for the treatment of migraine . Marketed under the brand name Imitrex .
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Sweating: The act of secreting fluid from the skin by the sweat (sudoriferous) glands. These are small tubular glands situated within and under the skin (in the subcutaneous tissue). They discharge by tiny openings in the surface of the skin.
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Symptom: Any subjective evidence of disease. Anxiety, lower back pain , and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.
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Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Temple: An area just behind and to the side of the forehead and the eye, above the side of the check bone (the zygomatic arch) and in front of the ear.
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Tension: 1) The pressure within a vessel , such as blood pressure : the pressure within the blood vessels. For example, elevated blood pressure is referred to as hypertension . 2) Stress, especially stress that is translated into clenched scalp muscles and bottled-up emotions or anxiety. This is the type of tension blamed for tension headaches.
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Therapy: The treatment of disease .
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Tinnitus : "Ringing in the ears" or another noise that seems to originate in the ears or head.
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Tired: A feeling of a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a sense of weariness and fatigue.
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Toddler: A young child who is learning to walk with short unsteady steps. The word toddle is of unknown origin.
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Torticollis: The most common of the focal dystonias, torticollis is a state of excessive of inadequate muscle tone in the muscles in the neck that control the position of the head. It can cause the head to twist and turn to one side, and the head may also be pulled forward or backward.
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Trauma: Any injury , whether physically or emotionally inflicted. "Trauma" has both a medical and a psychiatric definition. Medically, "trauma" refers to a serious or critical bodily injury, wound, or shock . This definition is often associated with trauma medicine practiced in emergency rooms and represents a popular view of the term. In psychiatry , "trauma" has assumed a different meaning and refers to an experience that is emotionally painful, distressful, or shocking, which often results in lasting mental and physical effects.
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Trigger: Something that either sets off a disease in people who are genetically predisposed to developing the disease, or that causes a certain symptom to occur in a person who has a disease. For example, sunlight can trigger rashes in people with lupus .
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Triptan: A class of drugs introduced in the 1990s for the treatment of migraine that act as agonists for 5-hydroxytryptamine ( 5-HT ) receptors. The triptans are often very effective in relieving migraine but do not prevent future attacks or lessen their frequency.
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Tumor: An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be benign or malignant (cancerous). There are dozens of different types of tumors. Their names usually reflect the kind of tissue they arise in, and may also tell you something about their shape or how they grow. For example, a medulloblastoma is a tumor that arises from embryonic cells (a blastoma) in the inner part of the brain (the medulla). Diagnosis depends on the type and location of the tumor. Tumor marker tests and imaging may be used; some tumors can be seen (for example, tumors on the exterior of the skin) or felt (palpated with the hands).
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Tylenol: See: Acetaminophen .
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Unilateral: Having, or relating to, one side. Unilateral is as opposed, for example, to bilateral (which means having, or relating to, two sides).
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Vasodilation: Widening of blood vessels resulting from relaxation of the muscular wall of the vessels. What widens is actually the diameter of the interior (the lumen) of the vessel. The opposite of vasoconstriction.
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Vertical: In anatomy, upright. As opposed to horizontal.
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Vertigo: Aside from being the name of a classic 1958 Alfred Hitchcock film (with Jimmy Stewart and Kim Novak), vertigo is a feeling that you are dizzily turning around or that things are dizzily turning about you. Vertigo is usually due to a problem with the inner ear. Vertigo can also be caused by vision problems.
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Vital: Necessary to maintain life. Breathing is a vital function.
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Voluntary: Done in accordance with the conscious will of the individual. The opposite of involuntary.
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Vomit: Matter from the stomach that has come up into and may be ejected beyond the mouth, due to the act of vomiting.
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Water retention: A nonspecific term meaning the accumulation of excess fluids in body tissues, medically known as edema . Edema can result from many different disease processes, including but not limited to diseases of the heart and circulation and kidney disease.
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Withdrawal symptoms: Abnormal physical or psychological features that follow the abrupt discontinuation of a drug that has the capability of producing physical dependence. Common withdrawal symptoms include sweating, tremor , vomiting, anxiety , insomnia , and muscle pain .
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Zolmitriptan: A triptan drug for the treatment of migraine . Marketed under the brand name Zomig .
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Zomig: Brand name for zolmitriptan , a triptan drug for the treatment of migraine .
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