Mononucleosis Glossary of Medical Terms

Abdominal: Relating to the abdomen, the belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
See the entire definition of Abdominal

Abdominal pain: Pain in the belly (the abdomen). Abdominal pain can come from conditions affecting a variety of organs. The abdomen is an anatomical area that is bounded by the lower margin of the ribs above, the pelvic bone (pubic ramus) below, and the flanks on each side. Although abdominal pain can arise from the tissues of the abdominal wall that surround the abdominal cavity (the skin and abdominal wall muscles), the term abdominal pain generally is used to describe pain originating from organs within the abdominal cavity (from beneath the skin and muscles). These organs include the stomach, small intestine, colon, liver, gallbladder, and pancreas.
See the entire definition of Abdominal pain

Acetaminophen: A pain reliever and fever reducer. Brand name: Tylenol. The exact mechanism of action of acetaminophen is not known. Acetaminophen relieves pain by elevating the pain threshold (that is, by requiring a greater amount of pain to develop before it is felt by a person). Acetaminophen reduces fever through its action on the heat-regulating center (the "thermostat") of the brain. Generic is available.
See the entire definition of Acetaminophen

Airway: The path air follows to get into and out of the lungs. The mouth and nose are the normal entry and exit ports. Entering air then passes through the back of the throat (pharynx), continues through the voice box (larynx), down the trachea, and finally out the branching tubes known as bronchi.
See the entire definition of Airway

Airway obstruction: Partial or complete blockage of the breathing tubes to the lungs. Obstruction of the airway can be due to different causes including foreign bodies, allergic reactions, infections, anatomical abnormalities and trauma.
See the entire definition of Airway obstruction

Anemia: The condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen-carrying capacity of the blood is, therefore, decreased.
See the entire definition of Anemia

Antibody: An immunoglobulin, a specialized immune protein , produced because of the introduction of an antigen into the body, and which possesses the remarkable ability to combine with the very antigen that triggered its production.
See the entire definition of Antibody

Arms: An appendage in anatomy and in clinical trials . See: Arm .
See the entire definition of Arms

Atypical: Not typical, not usual, not normal, abnormal. Atypical is often used to refer to the appearance of precancerous or cancerous cells.
See the entire definition of Atypical

Autoimmune: Pertaining to autoimmunity, a misdirected immune response that occurs when the immune system goes awry and attacks the body itself.
See the entire definition of Autoimmune

Autoimmune hemolytic anemia: A condition in which the immune system attacks the red blood cells , resulting in fewer of these oxygen-transporting cells. See also: Hemolytic anemia .
See the entire definition of Autoimmune hemolytic anemia

Autoimmune process: A process in which the body's immune system attacks and destroys body tissue that it mistakes for foreign matter. See also: Autoimmune disease ; and Autoimmunity .
See the entire definition of Autoimmune process

Bell's palsy: Paralysis of the facial nerve, the nerve that supplies the facial muscles on one side of the face. Bell's palsy is also called facial nerve paralysis.
See the entire definition of Bell's palsy

Blood count: The calculated number of white or red blood cells (WBCs or RBCs) in a cubic millimeter of blood.
See the entire definition of Blood count

Breathing: The process of respiration, during which air is inhaled into the lungs through the mouth or nose due to muscle contraction, and then exhaled due to muscle relaxation.
See the entire definition of Breathing

Burkitt's lymphoma: See: Burkitt lymphoma .
See the entire definition of Burkitt's lymphoma

Carcinoma: Cancer that begins in the skin or in tissues that line or cover body organs. For example, carcinoma can arise in the breast , colon, liver, lung, prostate, and stomach.
See the entire definition of Carcinoma

Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane .
See the entire definition of Cell

Chest: The area of the body located between the neck and the abdomen . The chest contains the lungs , the heart and part of the aorta . The walls of the chest are supported by the dorsal vertebrae , the ribs , and the sternum .
See the entire definition of Chest

Chest pain : There are many causes of chest pain. One is angina which results from inadequate oxygen supply to the heart muscle. Angina can be caused by coronary artery disease or spasm of the coronary arteries. Chest pain can also be due to a heart attack (coronary occlusion) and other important diseases such as, for example, dissection of the aorta and a pulmonary embolism . Do not try to ignore chest pain and "work (or play) though it." Chest pain is a warning to seek medical attention.
See the entire definition of Chest pain

Complete blood count : A set values of the cellular (formed elements) of blood. These measurements are generally determined by specially designed machines that analyze the different components of blood in less than a minute.
See the entire definition of Complete blood count

Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.
See the entire definition of Complication

Cranial: 1. Pertaining to the cranium or skull. 2. Toward the head. As opposed to caudad. The eye is cranial to the jaw. For a more complete listing of terms used in medicine for spatial orientation, please see the entry to " Anatomic Orientation Terms ".
See the entire definition of Cranial

Dehydration : Excessive loss of body water. Diseases of the gastrointestinal tract that cause vomiting or diarrhea may, for example, lead to dehydration. There are a number of other causes of dehydration including heat exposure, prolonged vigorous exercise (e.g., in a marathon), kidney disease, and medications (diuretics).
See the entire definition of Dehydration

Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
See the entire definition of Diagnosis

EBV: Epstein-Barr virus , best known as the cause of infectious mononucleosis (" mono ").
See the entire definition of EBV

Encephalitis: Inflammation of the brain. Encephalitis occurs, for example, in 1 in 1,000 cases of measles . It may start (up to 3 weeks) after onset of the measles rash and present with high fever , convulsions, and coma. It usually runs a blessedly short course with full recovery within a week. Or it may eventuate in central nervous system impairment or death.
See the entire definition of Encephalitis

Enlarged spleen: Splenomegaly , or an enlargement of the spleen . This condition can occur with different medical conditions ranging from blood disorders to infections and certain forms of cancer .
See the entire definition of Enlarged spleen

Enzyme: A protein (or protein-based molecule) that speeds up a chemical reaction in a living organism. An enzyme acts as catalyst for specific chemical reactions , converting a specific set of reactants (called substrates) into specific products. Without enzymes, life as we know it would not exist.
See the entire definition of Enzyme

Epstein-Barr virus: A virus , abbreviated EBV, best known as the cause of infectious mononucleosis (" mono ").
See the entire definition of Epstein-Barr virus

Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.
See the entire definition of Fatigue

Fever : Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
See the entire definition of Fever

Genital: Pertaining to the external and internal organs of reproduction. (Not to be confused with genetic.)
See the entire definition of Genital

Headache : A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
See the entire definition of Headache

Heart: The muscle that pumps blood received from veins into arteries throughout the body. It is positioned in the chest behind the sternum (breastbone; in front of the trachea, esophagus, and aorta; and above the diaphragm muscle that separates the chest and abdominal cavities. The normal heart is about the size of a closed fist, and weighs about 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest with the balance in the right chest.
See the entire definition of Heart

Hemolytic: Referring to hemolysis, the destruction of red blood cells which leads to the release of hemoglobin from within the red blood cells into the blood plasma .
See the entire definition of Hemolytic

Hemolytic anemia: Anemia due to the destruction (rather than underproduction) of red blood cells.
See the entire definition of Hemolytic anemia

Hepatitis: Inflammation of the liver from any cause.
See the entire definition of Hepatitis

Herpes: A family of viruses. Herpes also refers to infection with one of the human herpesviruses, especially herpes simplex types 1 and 2.
See the entire definition of Herpes

Hygiene: The science of preventive medicine and the preservation of health. From the name of Hygeia, the daughter of Asklepios, the Greek god of medicine (whose staff with entwined snake is the symbol of medicine). Asklepios (known to the Romans as Aesculapius) had a number of children including not only Hygeia but also Panaceia, the patroness of clinical medicine. Hygeia also followed her father into medicine. As the patroness of health, Hygeia was charged with providing a healthy environment to prevent illness. In Greek, "hygieia" means health.
See the entire definition of Hygiene

Ibuprofen: A non-steroidal anti-inflammatory drug (NSAID) commonly used to treat pain, swelling, and fever . Common brand names for Ibuprofen include Advil, Motrin, and Nuprin.
See the entire definition of Ibuprofen

Immunity: The condition of being immune. Immunity can be innate (for example, humans are innately immune to canine distemper) or conferred by a previous infection or immunization.
See the entire definition of Immunity

Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
See the entire definition of Infection

Infectious mononucleosis: A specific viral infection (with the Epstein-Barr virus) in which there is an increase of white blood cells that are mononuclear (with a single nucleus) "Mono" and "kissing disease" are popular terms for this very common illness caused by the Epstein-Barr virus (EBV). By the time most people reach adulthood, an antibody against EBV can be detected in their blood meaning they have been infected with EBV. The illness is less severe in young children. The infection can be spread by saliva. The incubation period for infectious mononucleosis is 4 to 8 weeks. Symptoms include fever , fatigue, sore throat , and swollen lymph glands. "Mono" can cause liver inflammation (hepatitis) and spleen enlargement. Vigorous contact sports should be avoided to prevent spleen rupture.
See the entire definition of Infectious mononucleosis

Jaundice: Yellow staining of the skin and sclerae (the whites of the eyes) by abnormally high blood levels of the bile pigment bilirubin . The yellowing extends to other tissues and body fluids. Jaundice was once called the "morbus regius" (the regal disease) in the belief that only the touch of a king could cure it.
See the entire definition of Jaundice

Kissing disease: A name for infectious mononucleosis ("mono"), a very common illness caused by the Epstein-Barr virus (EBV). By the time most people reach adulthood, an antibody against EBV can be detected in their blood meaning they have been infected with EBV. The illness is less severe in young children. The infection can be spread by saliva. The incubation period for "mono" is 4 to 8 weeks. Symptoms include fever , fatigue, sore throat , and swollen lymph glands. "Mono" can cause liver inflammation (hepatitis) and spleen enlargement. Vigorous contact sports should be avoided to prevent spleen rupture.
See the entire definition of Kissing disease

Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."
See the entire definition of Laboratory

Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.

See the entire definition of Liver

Lungs: The lungs are a pair of breathing organs located with the chest which remove carbon dioxide from and bring oxygen to the blood. There is a right and left lung.
See the entire definition of Lungs

Lymph: An almost colorless fluid that travels through vessels called lymphatics in the lymphatic system and carries cells that help fight infection and disease.
See the entire definition of Lymph

Lymph node: Also sometimes referred to as lymph glands, lymph nodes are small rounded or bean-shaped masses of lymphatic tissue surrounded by a capsule of connective tissue . Lymph nodes are located in many places in the lymphatic system throughout the body. Lymph nodes filter the lymphatic fluid and store special cells that can trap cancer cells or bacteria that are traveling through the body in the lymph fluid. The lymph nodes are critical for the body's immune response and are principal sites where many immune reactions are initiated. During a physical examination, doctors often look for swollen lymph nodes in areas where lymph nodes are abundant, including the neck, around the collarbone , the armpit ( axilla ), and the groin .
See the entire definition of Lymph node

Lymphoma: Tumor of the lymphoid tissue. Diagnosis is by biopsy. Treatment may be chemotherapy , radiation, surgery, or medication, depending on the age of the patient and type of tumor.
See the entire definition of Lymphoma

Malaise: A vague feeling of discomfort, one that cannot be pinned down but is often sensed as "just not right."
See the entire definition of Malaise

Meningitis: Inflammation of the meninges, usually due to a bacterial infection but sometimes from viral, protozoan, or other causes (in some cases the cause cannot be determined).
See the entire definition of Meningitis

Mono: Popular name for infectious mononucleosis .
See the entire definition of Mono

Mononucleosis: Infection with the Epstein-Barr virus (EBV, human herpesvirus 4, HHV-4) in which there is an increase of white blood cells that have a single nucleus (monocytes). The infection can be spread by saliva. Its incubation period is four to eight weeks. Symptoms include fever , fatigue, sore throat , and swollen lymph glands. Mononucleosis can cause liver inflammation (hepatitis) and spleen enlargement; vigorous contact sports should be avoided to prevent spleen rupture. It is less severe in young children.
See the entire definition of Mononucleosis

Myelitis: Inflammation of the spinal cord.
See the entire definition of Myelitis

Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system .
See the entire definition of Nerve

Node: Literally a knot, a node is a collection of tissue. For example a lymph node, is a collection of lymphoid tissue. A nodule is a small node, a little collection of tissue.
See the entire definition of Node

Obstruction: Blockage of a passageway. See, for example: Airway obstruction ; Intestinal obstruction .
See the entire definition of Obstruction

Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis . There is always an onset to a disease but never to the return to good health. The default setting is good health.
See the entire definition of Onset

Organ: A relatively independent part of the body that carries out one or more special functions. The organs of the human body include the eye , ear , heart , lungs , and liver .
See the entire definition of Organ

Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
See the entire definition of Pain

Palsy: Paralysis, generally partial, whereby a local body area is incapable of voluntary movement (motor function). For example, Bell's palsy is localized paralysis of the muscles on one side of the face. The word "palsy" is a corruption (and contracture) of the French word "paralysie" which means "paralysis."
See the entire definition of Palsy

Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.
See the entire definition of Pharmacy

Qualitative: Having to do with quality. In contrast to quantitative (which pertains to quantity, the amount).
See the entire definition of Qualitative

Rash : Breaking out (eruption) of the skin. Medically, a rash is referred to as an exanthem.
See the entire definition of Rash

Red blood cells: The blood cells that carry oxygen. Red cells contain hemoglobin and it is the hemoglobin which permits them to transport oxygen (and carbon dioxide). Hemoglobin, aside from being a transport molecule, is a pigment. It gives the cells their red color (and their name).
See the entire definition of Red blood cells

Rupture: A break or tear in any organ (such as the spleen ) or soft tissue (such as the achilles tendon ). Rupture of the appendix is more likely among uninsured and minority children when they develop appendicitis .
See the entire definition of Rupture

Ruptured spleen: Rupture of the capsule of the spleen, an organ in the upper left part of the abdomen, is a potential catastrophe that requires immediate medical and surgical attention. Splenic rupture permits large amounts of blood to leak into the abdominal cavity which is severely painful and life-threatening. Shock and, ultimately, death can result. Patients typically require an urgent operation. Rupture of a normal spleen can be caused by trauma, for example, in an accident. If an individual's spleen is enlarged, as is frequent in mononucleosis, most physicians will not allow activities (such as major contact sports) where injury to the abdomen could be catastrophic.
See the entire definition of Ruptured spleen

Saliva: a watery secretion in the mouth produced by the salivary glands that aids in the digestion of food. Saliva also serves to moisten and cleanse the mouth, including the tongue and teeth, and contains substances that can play a role in the prevention of infection . Saliva aids digestion by moistening food and contains enzymes that begin the digestion process. Also known as spit.
See the entire definition of Saliva

Sore: 1. (adjective) A popular term for painful. I have sore fingers from typing dictionary terms. She has a sore throat . 2. (noun) A nondescript term for nearly any lesion of the skin or mucous membranes. He has a number of sores in his mouth.

See the entire definition of Sore

Sore throat : Pain in the throat. Sore throat may be caused by many different causes, including inflammation of the larynx, pharynx, or tonsils.
See the entire definition of Sore throat

Spleen: An organ located in the upper left part of the abdomen near the stomach . The spleen produces lymphocytes ; it is the largest lymphatic organ in the body. The spleen also filters the blood, serves as a major reservoir for blood and destroys blood cells that are aged.
See the entire definition of Spleen

Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
See the entire definition of Surgery

Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
See the entire definition of Syndrome

Temple: An area just behind and to the side of the forehead and the eye, above the side of the check bone (the zygomatic arch) and in front of the ear.
See the entire definition of Temple

Throat: The throat is the anterior (front) portion of the neck beginning at the back of the mouth , consisting anatomically of the pharynx and larynx . The throat contains the trachea and a portion of the esophagus .
See the entire definition of Throat

Thrombocytopenia: A low platelet count. Platelets are irregular, disc-shaped element in the blood that assists in blood clotting. thrombocytopenia can arise due to decreased production of platelets in the bone marrow or increased breakdown of platelets in the bloodstream, spleen , or liver . Thrombocytopenia is characterized by easy bruising and increased bleeding.
See the entire definition of Thrombocytopenia

Tonsillitis: Inflammation of the of a tonsil, typically as a result of infection by either a virus or bacteria.
See the entire definition of Tonsillitis

Transverse: In anatomy, a horizontal plane passing through the standing body so that the transverse plane is parallel to the floor.
See the entire definition of Transverse

Transverse myelitis: A disease of the spinal cord in which there is demyelination (erosion of the myelin sheath that normally protects nerve fibers). The onset of the disorder is typically sudden. Symptoms include back pain followed by ascending weakness in the legs. There is no cure. Many patients are left with permanent disabilities or paralysis . Transverse myelitis occurs alone and in combination with demyelination of other parts of the nervous system . It may be associated with multiple sclerosis .
See the entire definition of Transverse myelitis

Tylenol: See: Acetaminophen .
See the entire definition of Tylenol

Ubiquitous: Present everywhere. The small protein called ubiquitin was so-named because it is present in all types of cells and its amino acid sequence is identical in all creatures from insects to humans.
See the entire definition of Ubiquitous

Vaccines: Microbial preparations of killed or modified microorganisms that can stimulate an immune response in the body to prevent future infection with similar microorganisms. These preparations are usually delivered by injection.
See the entire definition of Vaccines

Viral: Of or pertaining to a virus. For example, "My daughter has a viral rash ."
See the entire definition of Viral

Viral infection: Infection caused by the presence of a virus in the body. Depending on the virus and the person's state of health, various viruses can infect almost any type of body tissue, from the brain to the skin. Viral infections cannot be treated with antibiotics; in fact, in some cases the use of antibiotics makes the infection worse. The vast majority of human viral infections can be effectively fought by the body's own immune system , with a little help in the form of proper diet, hydration, and rest. As for the rest, treatment depends on the type and location of the virus, and may include anti-viral or other drugs.
See the entire definition of Viral infection

Virus: A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with errors (mutations)-this ability to mutate is responsible for the ability of some viruses to change slightly in each infected person, making treatment more difficult.
See the entire definition of Virus

Viruses: Small living particles that can infect cells and change how the cells function. Infection with a virus can cause a person to develop symptoms. The disease and symptoms that are caused depend on the type of virus and the type of cells that are infected.
See the entire definition of Viruses

White blood cell: One of the cells the body makes to help fight infections. There are several types of white blood cells ( leukocytes ). The two most common types are the lymphocytes and neutrophils (also called polymorphonuclear leukocytes, PMNs, or "polys").
See the entire definition of White blood cell

White blood cell count (leukocyte count): The number of white blood cells (WBCs) in the blood. The WBC is usually measured as part of the CBC ( complete blood count ). White blood cells are the infection-fighting cells in the blood and are distinct from the red (oxygen-carrying) blood cells known as erythrocytes. There are different types of white blood cells, including neutrophils (polymorphonuclear leukocytes ; PMNs), band cells (slightly immature neutrophils), T-type lymphocytes (T cells), B-type lymphocytes (B cells), monocytes, eosinophils, and basophils. All the types of white blood cells are reflected in the white blood cell count. The normal range for the white blood cell count varies between laboratories but is usually between 4,300 and 10,800 cells per cubic millimeter of blood. This can also be referred to as the leukocyte count and can be expressed in international units as 4.3 - 10.8 x 109 cells per liter.
See the entire definition of White blood cell count