Muscle Cramps Glossary of Terms

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Adjacent: Lying nearby. Related terms include superjacent, subjacent, and circumjacent. From ad-, near + the Latin jacere, to lie = to lie near.

Aging: The process of becoming older, a process that is genetically determined and environmentally modulated.
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Angina: Chest pain due to an inadequate supply of oxygen to the heart muscle. The chest pain of angina is typically severe and crushing. There is a feeling just behind the breastbone (the sternum) of pressure and suffocation.
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Ankle: The ankle joint is complex. It is made up of two joints: the true ankle joint and the subtalar joint:
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Asthma: A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways. Asthma involves only the bronchial tubes and does not affect the air sacs (alveoli) or the lung tissue (the parenchyma of the lung) itself.
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Atorvastatin: A medication that lowers the level of cholesterol in the blood. Atorvastatin is a statin drug. All statins prevent the production of cholesterol in the liver by blocking the enzyme that makes cholesterol, HMGCoA reductase. They lower total blood cholesterol as well as low-density lipoprotein (LDL) cholesterol levels. Lowering LDL cholesterol levels retards progression and may even reverse coronary artery disease. Unlike the other statins, atorvastatin can also reduce the concentration of triglycerides in the blood. (High blood concentrations of triglycerides have been associated with coronary artery disease.) The brand name of atorvastin is Lipitor.

Benign: Not cancer. Not malignant. A benign tumor does not invade surrounding tissue or spread to other parts of the body. A benign tumor may grow but it stays put (in the same place).
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Bile: Bile is a yellow-green fluid that is made by the liver, stored in the gallbladder and passes through the common bile duct into the duodenum where it helps digest fat. The principal components of bile are cholesterol, bile salts, and the pigment bilirubin.
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Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".

Botox: A highly purified preparation of botulinum toxin A, a toxin produced by the bacterium Clostridium botulinum. Botox is for injection, in very small amounts, into specific muscles. It acts by blocking the transmission of nerve impulses to muscles and so paralyzing the muscles. Botox is a brand name that has passed into popular usage as a synonym for Botulinum toxin.
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Botulism: An uncommon but potentially very serious illness, a type of food poisoning, that produces paralysis of muscles, via a nerve toxin called botulinum toxin ("botox") that is manufactured by bacteria named Clostridium botulinum.
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Calcium: A mineral found mainly in the hard part of bones, where it is stored. Calcium is added to bones by cells called osteoblasts and is removed from bones by cells called osteoclasts. Calcium is essential for healthy bones. It is also important for muscle contraction, heart action, nervous system maintenance, and normal blood clotting. Food sources of calcium include dairy foods, some leafy green vegetables such as broccoli and collards, canned salmon, clams, oysters, calcium-fortified foods, and tofu. According to the National Academy of Sciences, adequate intake of calcium is 1,200 milligrams a day (four glasses of milk) for men and women 51 and older, 1,000 milligrams a day for adults 19 through 50, and 1,300 milligrams a day for children 9 through 18. The upper limit for calcium intake is 2.5 grams daily.

Calf: The belly or fleshy hind part of the leg below the knee. The calf is made up mainly of the gastrocnemius muscle (which comes from the Greek "gastroknemia" meaning calf of the leg, from "gaster" (gastr-), belly, + "kneme," leg).
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Charley horse: A cramp in a muscle in the leg, usually caused by a strain or injury. A charley horse can last anywhere from a few seconds to a quarter of an hour, and occasionally longer. It is not uncommon for one to recur repeatedly before it finally goes away.
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Chest: The area of the body located between the neck and the abdomen. The chest contains the lungs, the heart and part of the aorta. The walls of the chest are supported by the dorsal vertebrae, the ribs, and the sternum.
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Cholesterol: The most common type of steroid in the body, cholesterol has gotten something of a bad name. However, cholesterol is a critically important molecule.
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Circulation: The movement of fluid in a regular or circuitous course. Although the noun "circulation" does not necessarily refer to the circulation of the blood, for all practical purposes today it does. Heart failure is an example of a problem with the circulation.

Claudication: Limping. The word "claudication" comes from the Latin "claudicare" meaning to limp. The Roman emperor Claudius (who ruled from A.D. 41-54) was so named because he limped, probably because of a birth defect.
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Contraction: The tightening and shortening of a muscle.

Cough: A rapid expulsion of air from the lungs typically in order to clear the lung airways of fluids, mucus, or material. Also called tussis.

Dehydration: Excessive loss of body water. Diseases of the gastrointestinal tract that cause vomiting or diarrhea may, for example, lead to dehydration. There are a number of other causes of dehydration including heat exposure, prolonged vigorous exercise (e.g., in a marathon), kidney disease, and medications (diuretics).
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Diuretic: Anything that promotes the formation of urine by the kidney. (The word "diuretic" comes from a combination of the Greek "dia-", thoroughly + "ourein", to urinate = to urinate thoroughly).
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Electrolyte: An electrolyte is a substance that will dissociate into ions in solution and acquire the capacity to conduct electricity. The electrolytes include sodium, potassium, chloride, calcium and phosphate. Informally, called lytes. (The clue to the word electrolyte is in the lyte which comes from the Greek lytos meaning that may be dissolved.)

Electromyogram: A test used to record the electrical activity of muscles. When muscles are active, they produce an electrical current that is usually proportional to the level of muscle activity. An electromyogram (EMG) is also called a myogram.
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Enzymes: Proteins that act as a catalysts in mediating and speeding a specific chemical reaction.
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Essential: 1. Something that cannot be done without.
2. Required in the diet, because the body cannot make it. As in an essential amino acid or an essential fatty acid.
3. Idiopathic. As in essential hypertension. "Essential" is a hallowed term meaning "We don't know the cause."

Extremity: The extremities in medical language are not freezing cold or scorching heat but rather the uttermost parts of the body. The extremities are simply the hands and feet.
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Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.
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Groin: In anatomy, the area where the upper thigh meets the trunk. More precisely, the fold or depression marking the juncture of the lower abdomen and the inner part of the thigh.
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Hamstring: The prominent tendons at the back of the knee. They are the sidewalls of the hollow behind the knee. (This hollow is called the popliteal space). Both hamstrings connect to muscles that flex the knee. A pulled hamstring is a common athletic injury.
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Heart: The muscle that pumps blood received from veins into arteries throughout the body. It is positioned in the chest behind the sternum (breastbone; in front of the trachea, esophagus, and aorta; and above the diaphragm muscle that separates the chest and abdominal cavities. The normal heart is about the size of a closed fist, and weighs about 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest with the balance in the right chest.
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Heat cramps: Painful muscle spasms in the abdomen, arms, or legs following strenuous activity. The skin is usually moist and cool and the pulse is normal or slightly raised. Body temperature is mostly normal. Heat cramps often are caused by a lack of salt in the body, but salt replacement should not be considered without advice from a physician. Heat cramps usually affect people who sweat a lot during strenuous activity. The sweating depletes the body's salt and moisture. The low salt level in the muscles causes painful cramps. Heat cramps may also be a symptom of heat exhaustion.
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High blood pressure: Also known as hypertension, high blood pressure is, by definition, a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
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Hormone: A chemical substance produced in the body that controls and regulates the activity of certain cells or organs.
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Inflammation: A basic way in which the body reacts to infection, irritation or other injury, the key feature being redness, warmth, swelling and pain. Inflammation is now recognized as a type of nonspecific immune response.
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Injury: Harm or hurt. The term "injury" may be applied in medicine to damage inflicted upon oneself as in a hamstring injury or by an external agent on as in a cold injury. The injury may be accidental or deliberate, as with a needlestick injury. The term "injury" may be synonymous (depending on the context) with a wound or with trauma.

Internal medicine: A medical specialty dedicated to the diagnosis and medical treatment of adults. A physician who specializes in internal medicine is referred to as an internist. A minimum of seven years of medical school and postgraduate training are focused on learning the prevention, diagnosis, and treatment of diseases of adults. Subspecialties of internal medicine include allergy and immunology, cardiology (heart), endocrinology (hormone disorders), hematology (blood disorders), infectious diseases, gastroenterology (diseases of the gut), nephrology (kidney diseases), oncology (cancer), pulmonology (lung disorders), and rheumatology (arthritis and musculoskeletal disorders).

Involuntary: Done other than in accordance with the conscious will of the individual. The opposite of voluntary.
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LDH: Lactate dehydrogenase.

Leg: In popular usage, the leg extends from the top of the thigh down to the foot. However, in medical terminology, the leg refers to the portion of the lower extremity from the knee to the ankle.
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Lipitor: See: Atorvastatin.

Magnesium: A mineral involved in many processes in the body including nerve signaling, the building of healthy bones, and normal muscle contraction. About 350 enzymes are known to depend on magnesium.
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Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."

Muscle cramp: An involuntarily and forcibly contracted muscle that does not relax. When we use the muscles such as those of our arms and legs that can voluntarily be controlled, they alternately contract and relax as we move our limbs. Muscles that support our head, neck, and trunk contract similarly in a synchronized fashion to maintain our posture. A muscle (or even a few fibers of a muscle) that involuntarily (without consciously willing it) contracts is called a "spasm." If the spasm is forceful and sustained, it becomes a cramp. Muscle cramps can last anywhere from a few seconds to a quarter of an hour, and occasionally longer. It is not uncommon for a cramp to recur multiple times until it finally goes away. The cramp may involve a part of a muscle, the entire muscle, or several muscles that usually act together, such as those that flex adjacent fingers. Some cramps involve the simultaneous contraction of muscles that ordinarily move body parts in opposite directions. Muscle cramps are very common and become increasingly frequent with age. Any muscle under voluntary control (skeletal muscle) can cramp. The legs and feet, and particularly the calf (the classic "charley horse"), are especially subject to cramps.

Myasthenia gravis: An autoimmune neuromuscular disorder characterized by fatigue and exhaustion of muscles. Myasthenia gravis is caused by a mistaken immune response to the nicotinic acetylcholine receptors (AChR), which are found in junctions between muscles and the nervous system. The body produces antibodies that attack these AChR receptors, preventing signals from reaching the muscles. Proof that the anti-AChR antibodies are responsible for myasthenia comes from the effect these antibodies can have on the unborn and the newborn.
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Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system.

Neurologist: A doctor who specializes in the diagnosis and treatment of disorders of the nervous system.

Nutrition: 1) The science or practice of taking in and utilizing foods. 2) A nourishing substance, such as nutritional solutions delivered to hospitalized patients via an IV or IG tube.

Osteoporosis: Thinning of the bones with reduction in bone mass due to depletion of calcium and bone protein. Osteoporosis predisposes a person to fractures, which are often slow to heal and heal poorly. It is more common in older adults, particularly post-menopausal women; in patients on steroids; and in those who take steroidal drugs. Unchecked osteoporosis can lead to changes in posture, physical abnormality (particularly the form of hunched back known colloquially as "dowager's hump"), and decreased mobility.
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia. Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Palpable: Something that can be felt or touched. For example, a palpable tumor is one that can be felt. From the Latin "palpare" (to stroke or to pat).

Pantothenic acid: Pantothenic acid is vitamin B5, one of the less well known B vitamins, perhaps because it is widely distributed in nature.
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Perspiration: 1) The secretion of fluid by the sweat (sudoriferous) glands. These small, tubular glands are situated within the skin, as well as in the subcutaneous tissue under it. They discharge their fluid through tiny openings in the surface of the skin. Perspiration serves at least two purposes: the removal of waste products such as urea and ammonia, and cooling of the body temperature as sweat evaporates. 2) The transparent, colorless, acidic fluid secreted by the sweat glands. It contains some fatty acids and mineral matter. Adult perspiration gains its characteristic odor from the waste products excreted. Also known as sweat.

Phosphorus: An essential element in the diet and a major component of bone. Phosphorus is also found in the blood, muscles, nerves, and teeth. It is a component of adenosine triphosphate (ATP), the primary energy source in the body.

Poor circulation: An inadequacy of blood flow. Inadequate blood flow to a particular area of the body can result in too little oxygen being delivered to that area, a condition known as hypoxia. The term poor circulation may be used to refer to peripheral vascular disease (or peripheral arterial disease), a condition that develops when the arteries that supply blood to the internal organs, arms, and legs become completely or partially blocked as a result of atherosclerosis.

Postmenopausal: After the menopause. Postmenopausal is defined formally as the time after which a woman has experienced twelve (12) consecutive months of amenorrhea (lack of menstruation) without a period.
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Posture: The carriage of the body as a whole, the attitude of the body, or the position of the limbs (the arms and legs).
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Potassium: The major positive ion (cation) found inside of cells. The chemical notation for potassium is K⁺.
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Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Pyridoxine: One of the vitamin B6 group (which also includes pyridoxal and pyridoxamine) that is transformed in the body to pyridoxal phosphate, which functions as a coenzyme, a substance that enhances the action of an enzyme and thereby helps catalyze and speed a biochemical reaction. (A number of vitamins serve as coenzymes.)
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Quinine: The original antimalarial agent, quinine took its name from the Peruvian Indian word "kina" meaning "bark of the tree" referring to the cinchona tree. From this tree, quinine was first obtained. The Peruvian Indians called it "the fever tree."
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Recur: To occur again. To return. Any symptom (such as fatigue), any sign (such as a heart murmur), or any disease can recur.

Rehydration: The process of restoring lost water to the body tissues and fluids. Prompt rehydration is imperative whenever dehydration occurs, from diarrhea, exposure, lack of drinking water, or medication use. Rehydration can be by the oral route or by the intravenous administration of fluids.

Shin: 1. The tibia, the larger of the two bones in the lower leg.
2. The anterior aspect (front) of the tibia.

Skeletal: Pertaining to the skeleton, the bones of the body which collectively provide the framework for the body.

Skeletal muscle: One of three types of muscle tissue in the body (skeletal, smooth, cardiac) which represents the majority of the muscular tissue in the body. Skeletal muscle is the type of muscle which powers movement of the skeleton as in walking and lifting.

Sodium: The major positive ion (cation) in fluid outside of cells. The chemical notation for sodium is Na⁺. When combined with chloride, the resulting substance is table salt.
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Spasm: A brief, automatic jerking movement. A muscle spasm can be quite painful, with the muscle clenching tightly. A spasm of the coronary artery can cause angina. Spasms in various types of tissue may be caused by stress, medication, over-exercise, or other factors.

Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine.
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Therapeutic: Relating to therapeutics, that part of medicine concerned specifically with the treatment of disease. The therapeutic dose of a drug is the amount needed to treat a disease.
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Thiamine: Vitamin B1. Thiamine (vitamin B1) acts as a coenzyme in the metabolism of the body. Deficiency of thiamine leads to beriberi, a syndrome characterized by inflammation of multiple nerves (polyneuritis), heart disease (cardiopathy), and edema (swelling).

Thyroid: 1. The thyroid gland. Also, pertaining to the thyroid gland. 2. A preparation of the thyroid gland used to treat hypothyroidism. 3. Shaped like a shield. (The thyroid gland was so-named by Thomas Wharton in 1656 because it was shaped like an ancient Greek shield.)
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Toxin: One of a number of poisons produced by certain plants, animals, and bacteria.
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Urine: Liquid waste. The urine is a clear, transparent fluid. It normally has an amber color. The average amount of urine excreted in 24 hours is from 40 to 60 ounces (about 1,200 cubic centimeters). Chemically, the urine is mainly an aqueous (watery) solution of salt (sodium chloride) and substances called urea and uric acid. Normally, it contains about 960 parts of water to 40 parts of solid matter. Abnormally, it may contain sugar (in diabetes), albumen (a protein) (as in some forms of kidney disease), bile pigments (as in jaundice), or abnormal quantities of one or another of its normal components.

Uterus: The uterus (womb) is a hollow, pear-shaped organ located in a woman's lower abdomen between the bladder and the rectum. The narrow, lower portion of the uterus is the cervix; the broader, upper part is the corpus. The corpus is made up of two layers of tissue.

Vessel: A tube in the body that carries fluids: blood vessels or lymph vessels.

Vitamins: The word "vitamin" was coined in 1911 by the Warsaw-born biochemist Casimir Funk (1884-1967). At the Lister Institute in London, Funk isolated a substance that prevented nerve inflammation (neuritis) in chickens raised on a diet deficient in that substance. He named the substance "vitamine" because he believed it was necessary to life and it was a chemical amine. The "e" at the end was later removed when it was recognized that vitamins need not be amines.
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Voluntary: Done in accordance with the conscious will of the individual. The opposite of involuntary.
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Writer's cramp: A dystonia that affects the muscles of the hand and sometimes the forearm and only occurs during handwriting. Similar focal dystonias have also been called typist's cramp, pianist's cramp, musician's cramp, and golfer's cramp.