Myeloma Glossary of Medical Terms

Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Access: 1. In general, a means of approaching something. 2. In health care, the opportunity or right to receive health care. 3. In dialysis , the point on the body where a needle or catheter is inserted to gain entry to the bloodstream.
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Adhesion: The union of two opposing tissue surfaces (often in reference to the sides of a wound). Also refers to scar tissue strands that can form in the area of a previous operation, such as within the abdomen after a laparotomy.
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Adjacent: Lying nearby. Related terms include superjacent , subjacent , and circumjacent . From ad- , near + the Latin jacere, to lie = to lie near.
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Aggressive: In oncology, quickly growing, tending to spread rapidly. As, for example, an aggressive tumor.
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Albumin: The main protein in human blood and the key to the regulation of the osmotic pressure of blood. Chemically, albumin is soluble in water, precipitated by acid, and coagulated by heat.
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Allogeneic: Taken from different individuals of the same species. Two or more individuals are said to be allogeneic to one another when the genes at one or more loci are not identical.
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Amyloid: Any of a number of complex proteins that are deposited in tissues and that share selected laboratory features such as a change in the fluorescence intensity of certain aromatic dyes like Congo Red.
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Amyloidosis : A disorder that results from the abnormal deposition of a particular protein, called amyloid, in various tissues of the body. Amyloid protein can be deposited in a localized area, and not be harmful, or in can cause serious changes in virtually any organ of the body.
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Analysis: A psychology term for processes used to gain understanding of complex emotional or behavioral issues.
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Anemia: The condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen-carrying capacity of the blood is, therefore, decreased.
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Angry: Pertaining to anger, an emotional state that may range in intensity from mild irritation to intense fury and rage. Anger has physical effects; it raises the heart rate and blood pressure and the levels of adrenaline and noradrenaline, and so on.
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Antibody: An immunoglobulin, a specialized immune protein , produced because of the introduction of an antigen into the body, and which possesses the remarkable ability to combine with the very antigen that triggered its production.
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Arm: 1. In popular usage, the appendage that extends from the shoulder to the hand. However, the medical definition refers to the upper extremity extending from the shoulder only to the elbow, excluding the forearm, which extends from the elbow to the wrist. The arm contains one bone: the humerus. 2. In a randomized clinical trial, any of the treatment groups. Most randomized trials have two "arms," but some have three "arms," or even more.
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Aspirate: To suck in. A patient may aspirate for example by accidentally drawing material from the stomach into the lungs. A doctor can aspirate a joint.
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Aspiration: Removal of a sample of fluid and cells through a needle. Aspiration also refers to the accidental sucking in of food particles or fluids into the lungs.
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Aspirin: A good example of a tradename that entered into the language, Aspirin was once the Bayer trademark for acetylsalicylic acid .
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Autologous: In blood transfusion and transplantation, a situation in which the donor and recipient are the same person.
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Back pain: Pain felt in the low or upper back. There are many causes of back pain.
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Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
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Blood: The familiar red fluid in the body that contains white and red blood cells , platelets , proteins , and other elements. The blood is transported throughout the body by the circulatory system . Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.
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Blood urea nitrogen: Abbreviated BUN. A measure primarily of the urea level in blood. Urea is cleared by the kidney. Diseases that compromise the function of the kidney frequently lead to an increased BUN.
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BMT: Bone marrow transplantation, a procedure in which doctors replace bone marrow that is diseased (or damaged) with healthy bone marrow. The bone marrow to be replaced may be deliberately destroyed by high doses of chemotherapy and/or radiation therapy. The replacement marrow may come from another person, or it may be the patient's own marrow (which was removed and stored before treatment). When marrow from an unrelated donor is used, the procedure is an allogeneic bone marrow transplantation. If the marrow is from an identical twin, it is termed syngeneic. Autologous bone marrow transplantation uses the patient's own marrow.
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Bone: Bone is the substance that forms the skeleton of the body. It is composed chiefly of calcium phosphate and calcium carbonate . It also serves as a storage area for calcium, playing a large role in calcium balance in the blood.
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Bone marrow: The soft blood-forming tissue that fills the cavities of bones and contains fat and immature and mature blood cells, including white blood cells, red blood cells, and platelets. Diseases or drugs that affect the bone marrow can affect the total counts of these cells.
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Bone marrow aspiration: The removal of a small amount of bone marrow (usually from the hip) through a needle. The needle is placed through the top layer of bone and a liquid sample containing bone marrow cells is obtained through the needle by aspirating (sucking) it into a syringe. The suction causes pain for a few moments. Bone marrow aspiration is done to diagnose and follow the progress of various conditions, including anemia and cancer , and to obtain marrow for transplantation.
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Bone marrow biopsy: The removal of a sample of bone marrow and a small amount of bone (usually from the hip) through a large needle. Two samples are taken. The first is bone marrow by aspiration (suction with a syringe). The second sample is a core biopsy to obtain bone marrow together with bone fibers. After the needle is removed, this solid sample is pushed out of the needle with a wire. Both samples are examined under a microscope to see the cells and architecture of the bone marrow.
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Bone marrow transplantation: See: Bone marrow transplant .
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Brain: That part of the central nervous system that is located within the cranium ( skull ). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called "hemispheres."
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Bruise: A bruise or "contusion" is an traumatic injury of the soft tissues which results in breakage of the local capillaries and leakage of red blood cells. In the skin it can be seen as a reddish-purple discoloration that does not blanch when pressed upon. When a bruise fades it becomes green and brown as the body metabolizes the blood cells in the skin. It is best treated with local application of a cold pack immediately after injury. Also called a contusion.
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BUN: Blood urea nitrogen. A measure primarily of the urea level in blood. Urea is cleared by the kidney and diseases which compromises the function of the kidney will frequently lead to increased blood levels. The blood BUN level can also rise in patients who are dehydrated.
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C-reactive protein: A plasma protein that rises in the blood with the inflammation from certain conditions.
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Calcium: A mineral found mainly in the hard part of bones, where it is stored. Calcium is added to bones by cells called osteoblasts and is removed from bones by cells called osteoclasts. Calcium is essential for healthy bones. It is also important for muscle contraction, heart action, nervous system maintenance, and normal blood clotting. Food sources of calcium include dairy foods, some leafy green vegetables such as broccoli and collards, canned salmon, clams, oysters, calcium-fortified foods, and tofu. According to the National Academy of Sciences, adequate intake of calcium is 1,200 milligrams a day (four glasses of milk) for men and women 51 and older, 1,000 milligrams a day for adults 19 through 50, and 1,300 milligrams a day for children 9 through 18. The upper limit for calcium intake is 2.5 grams daily.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Carbon dioxide: A gas which is the byproduct of cellular metabolism and which collects in the tissues, is cleared from the tissues by the blood within the veins, is carried by the hemoglobin in the red blood cells, and removed from the body via the lungs in the exhaled air. Abbreviated CO2.
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Catheter: A thin, flexible tube . For example, a catheter placed in a vein provides a pathway for giving drugs, nutrients, fluids, or blood products. Samples of blood can also be withdrawn through the catheter.
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CBC: A commonly used abbreviation in medicine that stands for complete blood count , a set values of the cellular (formed elements) of blood. These measurements are generally determined by specially designed machines that analyze the different components of blood in less than a minute.
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Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane .
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Central line: A catheter (tube) that is passed through a vein to end up in the thoracic (chest) portion of the vena cava (the large vein returning blood to the heart) or in the right atrium of the heart.
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Chemotherapy : 1. In the original sense, a chemical that binds to and specifically kills microbes or tumor cells. The term chemotherapy was coined in this regard by Paul Ehrlich (1854-1915).
2. In oncology, drug therapy for cancer. Also called "chemo" for short.
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Chest: The area of the body located between the neck and the abdomen . The chest contains the lungs , the heart and part of the aorta . The walls of the chest are supported by the dorsal vertebrae , the ribs , and the sternum .
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Chest pain: There are many causes of chest pain. One is angina which results from inadequate oxygen supply to the heart muscle. Angina can be caused by coronary artery disease or spasm of the coronary arteries. Chest pain can also be due to a heart attack (coronary occlusion) and other important diseases such as, for example, dissection of the aorta and a pulmonary embolism . Do not try to ignore chest pain and "work (or play) though it." Chest pain is a warning to seek medical attention.
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Chest X-ray: Commonly used to detect abnormalities in the lungs, but can also detect abnormalities in the heart, aorta, and the bones of the thoracic area. Metallic objects, such as jewelry are removed from the chest and neck areas for a chest x-ray to avoid interference with x-ray penetration and improve accuracy of the interpretation.
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Chromosome: A visible carrier of the genetic information.
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Clinical trial: See: Clinical trials . See also: Inconclusive clinical trial ; Negative clinical trial ; Non-inferior clinical trial ; Positive clinical trial .
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Clinical trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people.
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Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.
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Compression: 1. The act of pressing together. As in a compression fracture , nerve compression , or spinal cord compression.
2. To shorten in time. In embryology, there may be compression of development with some stages even omitted.
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Condition: The term "condition" has a number of biomedical meanings including the following:

1. An unhealthy state, such as in "this is a progressive condition."
2. A state of fitness, such as "getting into condition."
3. Something that is essential to the occurrence of something else; essentially a "precondition."
4. As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

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Congestive heart failure : Inability of the heart to keep up with the demands on it and, specifically, failure of the heart to pump blood with normal efficiency. When this occurs, the heart is unable to provide adequate blood flow to other organs such as the brain, liver and kidneys. Heart failure may be due to failure of the right or left or both ventricles. The signs and symptoms depend upon which side of the heart is failing. They can include shortness of breath (dyspnea), asthma due to the heart (cardiac asthma), pooling of blood (stasis) in the general body (systemic) circulation or in the liver's (portal) circulation, swelling ( edema ), blueness or duskiness (cyanosis), and enlargement (hypertrophy) of the heart.
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Consolidation therapy : Cancer treatment given after induction therapy to consolidate the gains obtained, further reduce the number of cancer cells and achieve a complete remission . Often just called consolidation.
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Constipation: Infrequent (and frequently incomplete) bowel movements. The opposite of diarrhea , constipation is commonly caused by irritable bowel syndrome, diverticulosis , and medications (constipation can paradoxically be caused by overuse of laxatives). Colon cancer can narrow the colon and thereby cause constipation. The large bowel (colon) can be visualized by barium enema x-rays, sigmoidoscopy, and colonoscopy. Barring a condition such as cancer, high-fiber diets can frequently relieve the constipation.
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Corticosteroid: Any of the steroid hormones made by the cortex (outer layer) of the adrenal gland. Cortisol is a corticosteroid.
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Creatinine: A chemical waste molecule that is generated from muscle metabolism. Creatinine is produced from creatine, a molecule of major importance for energy production in muscles. Approximately 2% of the body's creatine is converted to creatinine every day. Creatinine is transported through the bloodstream to the kidneys. The kidneys filter out most of the creatinine and dispose of it in the urine.
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CRP: C-reactive protein .
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Cryoglobulinemia: The presence in blood of abnormal proteins called cryoglobulins that, by definition, have the unusual properties of precipitating from the blood serum when it is chilled and redissolving upon rewarming. (Cryoglobulins are gamma globulins with a molecular weight of approximately 200,000.)
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Cure: 1. To heal, to make well, to restore to good health. Cures are easy to claim and, all too often, difficult to confirm.
2. A time without recurrence of a disease so that the risk of recurrence is small, as in the 5-year cure rate for malignant melanoma .
3. Particularly in the past, a course of treatment. For example, take a cure at a spa.
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Dehydration : Excessive loss of body water. Diseases of the gastrointestinal tract that cause vomiting or diarrhea may, for example, lead to dehydration. There are a number of other causes of dehydration including heat exposure, prolonged vigorous exercise (e.g., in a marathon), kidney disease, and medications (diuretics).
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Depression : An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Diarrhea : A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation . The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
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Donor: The giver of a tissue or organ, for example, of blood or a kidney.
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Dysfunction: Difficult function or abnormal function.
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Electrophoresis: A process by which molecules (such as proteins , DNA , or RNA fragments) can be separated according to size and electrical charge by applying an electric current to them. Each kind of molecule travels through the medium at a different rate, depending on its electrical charge and molecular size.
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Enzyme: A protein (or protein-based molecule) that speeds up a chemical reaction in a living organism. An enzyme acts as catalyst for specific chemical reactions , converting a specific set of reactants (called substrates) into specific products. Without enzymes, life as we know it would not exist.
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Erosion: An erosion is an eating away of a surface. ("Erodere" in Latin means to eat out.)
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Excision: 1. Surgical removal, as in the excision of a tumor . 2. The removal as if by surgery, as in base excision repair .
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Fatigue: A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.
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Fracture: A break in bone or cartilage. Although usually the result of trauma, a fracture can be caused by an acquired disease of bone such as osteoporosis or by abnormal formation of bone in a disease such as osteogenesis imperfecta ("brittle bone disease"). Fractures are classified according to their character and location as, for example, a greenstick fracture of the radius.
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Genetic: Having to do with genes and genetic information.
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Graft: Healthy skin, bone, or other tissue taken from one part of the body to replace diseased or injured tissue removed from another part of the body.
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Hair loss : Hair loss is the thinning of hair on the scalp. The medical term for hair loss is alopecia . Alopecia can be temporary or permanent. The most common form of hair loss occurs gradually and is referred to as “androgenetic alopecia,” meaning that a combination of hormones (androgens are male hormones) and heredity ( genetics ) is needed to develop the condition. Other types of hair loss include alopecia areata (patches of baldness that usually grow back), telogen effluvium (rapid shedding after childbirth, fever , or sudden weight loss); and traction alopecia (thinning from tight braids or ponytails).
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Headache : A pain in the head with the pain being above the eyes or the ears, behind the head (occipital), or in the back of the upper neck. Headache, like chest pain or back ache, has many causes.
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Heart: The muscle that pumps blood received from veins into arteries throughout the body. It is positioned in the chest behind the sternum (breastbone; in front of the trachea, esophagus, and aorta; and above the diaphragm muscle that separates the chest and abdominal cavities. The normal heart is about the size of a closed fist, and weighs about 10.5 ounces. It is cone-shaped, with the point of the cone pointing down to the left. Two-thirds of the heart lies in the left side of the chest with the balance in the right chest.
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Heart failure : Inability of the heart to keep up with the demands on it and, specifically, failure of the heart to pump blood with normal efficiency. When this occurs, the heart is unable to provide adequate blood flow to other organs such as the brain, liver and kidneys. Heart failure may be due to failure of the right or left or both ventricles. The signs and symptoms depend upon which side of the heart is failing. They can include shortness of breath (dyspnea), asthma due to the heart (cardiac asthma), pooling of blood (stasis) in the general body (systemic) circulation or in the liver's (portal) circulation, swelling ( edema ), blueness or duskiness (cyanosis), and enlargement (hypertrophy) of the heart.
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Hematocrit: The proportion of the blood that consists of packed red blood cells . The hematocrit is expressed as a percentage by volume. The red cells are packed by centrifugation.
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Hematologist: A physician who is specially trained in the diagnosis, treatment, and prevention of diseases of the blood and bone marrow as well as the immunologic, hemostatic (blood clotting) and vascular systems. Because of the nature of blood, the science of hematology profoundly affects the understanding of many diseases.
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Hemoglobin: The oxygen-carrying pigment and predominant protein in the red blood cells . Hemoglobin forms an unstable, reversible bond with oxygen. In its oxygenated state it is called oxyhemoglobin and is bright red. In the reduced state it is called deoxyhemoglobin and is purple-blue.
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Hospital: It may seem unnecessary to define a "hospital" since everyone knows the nature of a hospital. A hospital began as a charitable institution for the needy, aged, infirm, or young.
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Hypercalcemia: A higher-than-normal level of calcium in the blood. This can cause a number of nonspecific symptoms, including loss of appetite, nausea, thirst, fatigue, muscle weakness, restlessness, and confusion. Excessive intake of calcium may cause muscle weakness and constipation , affect the conduction of electrical impulses in the heart (heart block) lead to calcium stones (nephrocalcinosis), in the urinary tract, impair kidney function, and interfere with the absorption of iron predisposing to iron deficiency. According to the National Academy of Sciences, adequate intake of calcium is 1 gram daily for both men and women. The upper limit for calcium intake is 2.5 grams daily.
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Immune: Protected against infection. The Latin immunis means free, exempt.
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Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
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Immunoglobulin: A protein produced by plasma cells and lymphocytes and characteristic of these types of cells. Immunoglobulins play an essential role in the body's immune system. They attach to foreign substances, such as bacteria, and assist in destroying them. Immunoglobulin is abbreviated Ig. The classes of immunoglobulins are termed immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM), immunoglobulin D (IgD) and immunoglobulin E (IgE).
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Incidence: The frequency with which something, such as a disease, appears in a particular population or area. In disease epidemiology, the incidence is the number of newly diagnosed cases during a specific time period. The incidence is distinct from the prevalence which refers to the number of cases alive on a certain date.
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Indicate: In medicine, to make a treatment or procedure advisable because of a particular condition or circumstance. For example, certain medications are indicated for the treatment of hypertension during pregnancy while others are contraindicated .
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Induction therapy : Treatment designed as a first step toward reducing the number of cancer cells. Often just referred to as induction.
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Infuse: In medicine, to introduce a solution into the body through a vein. An infusion is the therapeutic introduction of a fluid other than blood into a vein. The infused fluid might, for example, be a saline (salt) solution.
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Interventional: Pertaining to the act of intervening, interfering or interceding with the intent of modifying the outcome. As, for example, an interventional radiologist .
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Irradiation: The use of high-energy radiation from x-rays, gamma rays, neutrons, and other sources to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external-beam radiation therapy) or from materials called radioisotopes. Radioisotopes produce radiation and can be placed in or near the tumor or in the area near cancer cells. This type of radiation treatment is called internal radiation therapy , implant radiation, interstitial radiation , or brachytherapy . Systemic radiation therapy uses a radioactive substance, such as a radiolabeled monoclonal antibody , that circulates throughout the body. Irradiation is also called radiation therapy, radiotherapy , and x-ray therapy.
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Joint: A joint is the area where two bones are attached for the purpose of motion of body parts. A joint is usually formed of fibrous connective tissue and cartilage. An articulation or an arthrosis is the same as a joint.
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Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.

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Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."
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Lactate dehydrogenase: (LDH) An enzyme that catalyzes the conversion of lactate to pyruvate. This is an important step in energy production in cells. Many different types of cells in the body contain this enzyme. Some of the organs relatively rich in LDH are the heart, kidney, liver, and muscle.
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LDH: Lactate dehydrogenase .
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Leg: In popular usage, the leg extends from the top of the thigh down to the foot. However, in medical terminology, the leg refers to the portion of the lower extremity from the knee to the ankle.
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Lesion: Pronounced "lee-sion" with the emphasis on the "lee," a lesion can be almost any abnormality involving any tissue or organ due to any disease or any injury.
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Lethargy: 1. Abnormal drowsiness, stupor. 2. A state of indifference.
From the Greek lethargia, drowsiness.
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Leukemia : Cancer of the blood cells. The growth and development of the blood cells are abnormal. Strictly speaking, leukemia should refer only to cancer of the white blood cells (the leukocytes) but in practice it can apply to malignancy of any cellular element in the blood or bone marrow, as in red cell leukemia (erythroleukemia).
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Limb: The arm or leg.
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Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.

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Local therapy: Treatment that affects only a tumor and the area close to it.
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Lymph: An almost colorless fluid that travels through vessels called lymphatics in the lymphatic system and carries cells that help fight infection and disease.
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Lymph node: Also sometimes referred to as lymph glands, lymph nodes are small rounded or bean-shaped masses of lymphatic tissue surrounded by a capsule of connective tissue . Lymph nodes are located in many places in the lymphatic system throughout the body. Lymph nodes filter the lymphatic fluid and store special cells that can trap cancer cells or bacteria that are traveling through the body in the lymph fluid. The lymph nodes are critical for the body's immune response and are principal sites where many immune reactions are initiated. During a physical examination, doctors often look for swollen lymph nodes in areas where lymph nodes are abundant, including the neck, around the collarbone , the armpit ( axilla ), and the groin .
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Lymphatics: Small thin channels similar to blood vessels that do not carry blood, but collect and carry tissue fluid (called lymph) from the body to ultimately drain back into the blood stream.
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Lymphocytes: A small white blood cell ( leukocyte ) that plays a large role in defending the body against disease.
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Lymphoma: Tumor of the lymphoid tissue. Diagnosis is by biopsy. Treatment may be chemotherapy , radiation, surgery, or medication, depending on the age of the patient and type of tumor.
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Lytic: Suffix having to do with lysis (destruction), as in hemolytic anemia , the excessive destruction of red blood cells leading to anemia.
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M protein: An antibody or part of an antibody found in unusually large amounts in the blood or urine of patients with multiple myeloma , a form of cancer that arises in plasma cells (white blood cells that produce antibodies).
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Magnetic resonance imaging : A special radiology technique designed to image internal structures of the body using magnetism, radio waves, and a computer to produce the images of body structures. In magnetic resonance imaging (MRI), the scanner is a tube surrounded by a giant circular magnet. The patient is placed on a moveable bed that is inserted into the magnet. The magnet creates a strong magnetic field that aligns the protons of hydrogen atoms, which are then exposed to a beam of radio waves. This spins the various protons of the body, and they produce a faint signal that is detected by the receiver portion of the MRI scanner. A computer processes the receiver information, and an image is produced. The image and resolution is quite detailed and can detect tiny changes of structures within the body, particularly in the soft tissue, brain and spinal cord, abdomen and joints.
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Maintenance therapy: Treatment designed to help the original primary treatment succeed. Maintenance chemotherapy may be given to patients with cancer in remission to prevent a relapse .
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Malignant: 1. Tending to be severe and become progressively worse, as in malignant hypertension. 2. In regard to a tumor, having the properties of a malignancy that can invade and destroy nearby tissue and that may spread (metastasize) to other parts of the body.
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Marker: A piece of DNA that lies on a chromosome so close to a gene that the marker and the gene are inherited together. A marker is thus an identifiable heritable spot on a chromosome. A marker can be an expressed region of DNA (a gene) or a segment of DNA with no known coding function. All that matters is that the marker can be detected and trailed.
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Marrow: The bone marrow .
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Metabolism: The whole range of biochemical processes that occur within us (or any living organism). Metabolism consists both of anabolism and catabolism (the buildup and breakdown of substances, respectively). The term is commonly used to refer specifically to the breakdown of food and its transformation into energy.
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Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.
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Monoclonal: Pertaining to a single clone of cells, a single cell and the progeny of that cell. As opposed to polyclonal.
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Morbidity: Illness, disease.
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Morphology: 1. Literally, the study of form. The study of structure.
2. The form itself, as of an organ or part of the body.
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Mortality: A fatal outcome or, in one word, death. The word "mortality" is derived from "mortal" which came from the Latin "mors" (death). The opposite of mortality is, of course, immortality. Mortality is also quite distinct from morbidity (illness).
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Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.
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MRI: Abbreviation and nickname for magnetic resonance imaging . For more information, see: Magnetic Resonance Imaging ; Paul C. Lauterbur ; Peter Mansfield .
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Multiple myeloma: A malignancy of plasma cells (a form of lymphocyte) that typically involves multiple sites within the bone morrow and secretes all or part of a monoclonal antibody . Also called plasma cell myeloma .
See the entire definition of Multiple myeloma

Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
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Myeloma: A tumor of antibody-producing cells, called plasma cells, that are normally found in the bone marrow.
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Nausea: Nausea, is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza , medications, pain, and inner ear disease. When nausea and/or vomiting are persistent, or when they are accompanied by other severe symptoms such as abdominal pain , jaundice , fever, or bleeding, a physician should be consulted.
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Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system .
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Nitrogen: Element number 7, a colorless, odorless, tasteless gas that is biologically important. Nitrogen is a constituent of protein and nucleic acids and is present in all living cells. Nitrogen does not support respiration and is fatal if breathed alone, because of the lack of oxygen . Nitrogen is soluble in the blood and body fluids and, when released as bubbles of gas, can have serious or even fatal consequences.
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Node: Literally a knot, a node is a collection of tissue. For example a lymph node, is a collection of lymphoid tissue. A nodule is a small node, a little collection of tissue.
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Nose: The external midline projection from the face.
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Oncologist: A physician who specializes in the diagnosis and treatment of cancer .
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Organ: A relatively independent part of the body that carries out one or more special functions. The organs of the human body include the eye , ear , heart , lungs , and liver .
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Orthopedist: An orthopaedic surgeon, orthopaedics being the branch of surgery broadly concerned with the skeletal system (bones). Orthopedics is how this field of surgery is listed under Physicians & Surgeons in the telephone Yellow Pages in Jacksonville, Florida. This spelling is quite common today. But it is incorrect, erroneous, flat out wrong. Orthopedics would relate the term to the foot because in Latin pedis means foot. Orthopaedics is not merely old-fashioned. It is the correct spelling. What was meant by the term orthopaedics when it was devised goes back to its roots: ortho-, straight + the Greek paes, child = the practice, literally, of straightening the child. If the child had a crooked spine ( scoliosis ), it was the job of the orthopaedist to straighten the child, not just the child's foot. That is why there is no American Academy of Orthopedic Surgery but there is an American Academy of Orthopaedic Surgery. And that is also why orthopaedists look after broken bones.
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Osteolytic: Pertaining to the dissolution of bone, especially the loss of calcium from bone. "Punched-out" osteolytic lesions are characteristic of metastatic lung and breast cancer and multiple myeloma .
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Osteolytic lesion: A "punched-out" area of severe bone loss. Osteolytic lesions are seen in metastatic lung and breast cancer and multiple myeloma and may cause bone pain, pathologic fractures (bones broken by disease), and hypercalcemia (high blood calcium).
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Osteoporosis: Thinning of the bones with reduction in bone mass due to depletion of calcium and bone protein . Osteoporosis predisposes a person to fractures, which are often slow to heal and heal poorly. It is more common in older adults, particularly post-menopausal women; in patients on steroids; and in those who take steroidal drugs. Unchecked osteoporosis can lead to changes in posture , physical abnormality (particularly the form of hunched back known colloquially as " dowager's hump "), and decreased mobility.
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Oxygen: A colorless, odorless and tasteless gas that makes up about 20% of the air we breathe (and at least half the weight of the entire solid crust of the earth) and which combines with most of the other elements to form oxides. Oxygen is essential to human, animal and plant life.
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PA-C: Physician Assistant - Certified.
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Paralysis: Loss of voluntary movement (motor function). Paralysis that affects only one muscle or limb is partial paralysis, also known as palsy; paralysis of all muscles is total paralysis, as may occur in cases of botulism .
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Pathologic: 1. Indicative of or caused by disease, as in a pathologic fracture , pathologic tissue , or pathologic process . 2. Pertaining to pathology , the branch of medicine that studies disease and especially the essential nature of disease.
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Pathologic fracture: A bone broken, not by trauma alone, but so weakened by disease as to break with abnormal ease. Pathologic fractures are characteristic of metastatic lung and breast cancer and myeloma .
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Pathologist: A doctor who identifies diseases by studying cells and tissues under a microscope.
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Pediatrics: "Pediatrics is concerned with the health of infants, children and adolescents, their growth and development, and their opportunity to achieve full potential as adults." (Richard E.Behrman in Nelson's Textbook of Pediatrics)
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Pelvis: The lower part of the abdomen located between the hip bones.
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Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.
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Plasma: The liquid part of the blood and lymphatic fluid, which makes up about half of its volume. Plasma is devoid of cells and, unlike serum, has not clotted. Blood plasma contains antibodies and other proteins. It is taken from donors and made into medications for a variety of blood-related conditions. Some blood plasma is also used in non-medical products.
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Plasma cell: A type of white blood cell that produces and secretes antibodies . A plasma cell is a fully differentiated lymphocyte in the B-cell (not the T-cell ) lineage. As with most cell types, plasma cells can mutate to give rise to cancer. Plasma cell malignancies include multiple myeloma , Waldenstrom macroglobulinemia , and plasma cell leukemia .
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Plasmacytoma: Cancer of the plasma cells (white blood cells that produce antibodies) that may turn into multiple myeloma .
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Platelet: An irregular, disc-shaped element in the blood that assists in blood clotting. During normal blood clotting, the platelets clump together (aggregate). Although platelets are often classed as blood cells, they are actually fragments of large bone marrow cells called megakaryocytes.
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Platelet count: The calculated number of platelets in a volume of blood, usually expressed as platelets per cubic millimeter (cmm) of whole blood. Platelets are the smallest cell-like structures in the blood and are important for blood clotting and plugging damaged blood vessels. Platelet counts are usually done by laboratory machines that also count other blood elements such as the white and red cells. They can also be counted by use of a microscope. Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 - 400 x 10⁹ per liter). These values many vary slightly between different laboratories.
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Precancerous: Pertaining to something that is not yet overtly cancerous, but appears to be on its way to becoming a cancer . Synonymous with premalignant.
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Pregnancy : The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Primary: First or foremost in time or development. The primary teeth (the baby teeth) are those that come first. Primary may also refer to symptoms or a disease to which others are secondary.
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Prognosis: 1. The expected course of a disease .
2. The patient's chance of recovery.
The prognosis predicts the outcome of a disease and therefore the future for the patient . His prognosis is grim, for example, while hers is good.
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Prognostic: 1. (adjective) In medicine, relating to the prognosis of a disease. For example, a favorable prognostic factor.
2. (adjective) Generally, relating to a prediction. For example, a prognostic index for the economy.
3. (noun) In medicine, an indicator of the course of a disease.
4. (noun) Any type of prediction.

The word prognostic is far more often used today as an adjective than as a noun. Prognostic is taken from the Greek prognostikos (of knowledge beforehand). It combines pro (before) and gnosis (a knowing). Hippocrates used the word prognosis, much as we do today, to mean a foretelling of the course of a disease.
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Progressive: Increasing in scope or severity. Advancing. Going forward. In medicine, a disease that is progressive is going from bad to worse.
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Proteasome: A protein degradation "machine" within the cell that can digest a variety of proteins into short polypeptides and amino acids. The proteasome is itself made up of proteins. It requires ATP to work. It is hollow and has openings at both ends to allow entry of the protein to be digested.
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Protein: A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
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Proteins: Large molecules composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein.
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Quality of life: An important consideration in medical care, quality of life refers to the patient's ability to enjoy normal life activities. Some medical treatments can seriously impair quality of life without providing appreciable benefit, while others greatly enhance quality of life.
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Radiation: 1. Rays of energy. Gamma rays and X-rays are two of the types of energy waves often used in medicine. 2. The use of energy waves to diagnose or treat disease. See also: Irradiation .
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Radiation oncologist: A specialist in the use of radiation therapy as a treatment for cancer.
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Radiation therapy : The use of high-energy rays to damage cancer cells, stopping them from growing and dividing. Like surgery, radiation therapy is a local treatment that affects cancer cells only in the treated area.
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RBC: Short for red blood cells, the cells that carry oxygen and carbon dioxide through the blood. This rather remarkable feat is thanks to hemoglobin , the pigment that makes red cells (and blood) look red. The red blood cells are also known as red corpuscles or erythrocytes (literally, red hollow vessels).
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Reabsorption: Absorbing again. For example, the kidney selectively reabsorbs substances such as glucose , proteins, and sodium which it had already secreted into the renal tubules. These reabsorbed substances return to the blood.
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Recur: To occur again. To return. Any symptom (such as fatigue), any sign (such as a heart murmur), or any disease can recur.
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Recurrence: The return of a sign, symptom or disease after a remission. The reappearance of cancer cells at the same site or in another location is, unfortunately, a familiar form of recurrence.
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Recurrent: Back again. A recurrent fever is a fever that has returned after an intermission: a recrudescent fever.
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Red blood cell: The blood cell that carries oxygen. Red cells contain hemoglobin and it is the hemoglobin which permits them to transport oxygen (and carbon dioxide). Hemoglobin, aside from being a transport molecule, is a pigment. It gives the cell its red color (and name).
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Red blood cells: The blood cells that carry oxygen. Red cells contain hemoglobin and it is the hemoglobin which permits them to transport oxygen (and carbon dioxide). Hemoglobin, aside from being a transport molecule, is a pigment. It gives the cells their red color (and their name).
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Red cell count: The number of red blood cells (RBCs) in a volume of blood. The normal range varies slightly between laboratories but is generally between 4.2 - 5.9 million cells/cmm. This can also be referred to as the erythrocyte count and can be expressed in international units as 4.2 - 5.9 x 10¹² cells per liter.
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Referral: The recommendation of a medical or paramedical professional. If you get a referral to ophthalmology, for example, you are being sent to the eye doctor. In HMOs and other managed care schemes, a referral is usually necessary to see any practitioner or specialist other than your primary care physician (PCP), if you want the service to be covered. The referral is obtained from your PCP, who may require a telephone or office consultation first.
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Refractory: Not yielding (at least not yielding readily) to treatment.
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Regimen: With the accent on the first syllable (reg as in Reggie Jackson), a regimen is a plan, a regulated course such as a diet, exercise or treatment, designed to give a good result. A low-salt diet is a regimen.
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Relapse: The return of signs and symptoms of a disease after a patient has enjoyed a remission . For example, after treatment a patient with cancer of the colon went into remission with no sign or symptom of the tumor, remained in remission for 4 years, but then suffered a relapse and had to be treated once again for colon cancer.
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Remission: Disappearance of the signs and symptoms of cancer or other disease. When this happens, the disease is said to be "in remission." A remission can be temporary or permanent.
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Renal: Having to do with the kidney. From the Latin renes (the kidneys), which gave the French les reins which mean both the kidneys and the lower back.
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Rest: 1. Repose. Relaxation.
2. A fragment of embryonic tissue that has been retained after the period of embryonic development. Also called an embryonic rest.
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Salvage therapy: 1. A final treatment for people who are nonresponsive to or cannot tolerate other available therapies for a particular condition and whose prognosis is often poor.
2. In oncology, a treatment given after a tumor has not responded to other treatments, or any treatment given after recurrence of a tumor.
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Samaritan: See Good Samaritan .
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Sensation: In medicine and physiology , sensation refers to the registration of an incoming ( afferent ) nerve impulse in that part of the brain called the sensorium , which is capable of such perception. Therefore, the awareness of a stimulus as a result of its perception by sensory receptors. (Sensory is here synonymous with sensation.)
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Sensitivity: 1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.
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Serum: The clear liquid that can be separated from clotted blood. Serum differs from plasma, the liquid portion of normal unclotted blood containing the red and white cells and platelets. It is the clot that makes the difference between serum and plasma.
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Sign: Any objective evidence of disease. Gross blood in the stool is a sign of disease. It can be recognized by the patient, doctor, nurse, or others. In contrast, a symptom is, by its nature, subjective. Abdominal pain is a symptom. It is something only the patient can know.
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Skeletal: Pertaining to the skeleton, the bones of the body which collectively provide the framework for the body.
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Skeleton: The skeleton is composed of bones and is the framework of the body.
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Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.

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Skull: The skull is a collection of bones which encase the brain and give form to the head and face. The bones of the skull include the following: the frontal, parietal, occipital, temporal, sphenoid, ethmoid, zygomatic, maxilla, nasal, vomer, palatine, inferior concha, and mandible.
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Spine: 1) The column of bone known as the vertebral column, which surrounds and protects the spinal cord. The spine can be categorized according to level of the body: i.e., cervical spine (neck), thoracic spine (upper and middle back), and lumbar spine (lower back). See also vertebral column. 2) Any short prominence of bone. The spines of the vertebrae protrude at the base of the back of the neck and in the middle of the back. These spines protect the spinal cord from injury from behind.
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Stage: As regards cancer , the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging .
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Staging: In regard to cancer, the process of doing examinations and tests to learn the extent of the cancer, especially whether it has metastasized (spread) from its original site to other parts of the body.
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Stem cell: One of the human body's master cells, with the ability to grow into any one of the body's more than 200 cell types.
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Stem cell transplantation: The use of stem cells as a treatment for cancer or other diseases:

1. The stem cells are removed (or obtained) from a donor.
2. Before a transplant is done for cancer, the patient receives high-dose chemotherapy and/or radiation to destroy the malignant cells.
3. The stem cells are then given to the patient in whom they can produce new blood and immune cells and replace the cells destroyed by the treatment.

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Stroke : The sudden death of some brain cells due to a lack of oxygen when the blood flow to the brain is impaired by blockage or rupture of an artery to the brain. A stroke is also called a cerebrovascular accident or, for short, a CVA.
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Substance: 1. Material with particular features, as a pressor substance .
2. The material that makes up an organ or structure. Also known in medicine as the substantia.
3. A psychoactive drug as, for example, in substance abuse .
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Supportive care: Treatment given to prevent, control, or relieve complications and side effects and to improve the patient's comfort and quality of life.
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Symptom: Any subjective evidence of disease. Anxiety, lower back pain , and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.
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Symptomatic: 1 With symptoms, as a symptomatic infection . 2 Characteristic, as behavior symptomatic of Huntington disease . 3 Directed at the symptoms, as symptomatic treatment .
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Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Systemic: Affecting the entire body. A systemic disease such as diabetes can affect the whole body. Systemic chemotherapy employs drugs that travel through the bloodstream and reach and affect cells all over the body.
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Systemic therapy: Treatment that reaches cells throughout the body by traveling through the bloodstream.
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Therapeutic: Relating to therapeutics , that part of medicine concerned specifically with the treatment of disease . The therapeutic dose of a drug is the amount needed to treat a disease.
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Therapy: The treatment of disease .
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Tissue: A tissue in medicine is not like a piece of tissue paper. It is a broad term that is applied to any group of cells that perform specific functions. A tissue in medicine need not form a layer. Thus,

• The bone marrow is a tissue;
• Connective tissue consists of cells that make up fibers in the framework supporting other body tissues; and
• Lymphoid tissue is the part of the body's immune system that helps protect it from bacteria and other foreign entities.

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Transfusion: The transfer of blood or blood products from one person (the donor) into another person (the recipient's) bloodstream. In most situations, this is done as a lifesaving maneuver to replace blood cells or blood products lost through severe bleeding. Transfusion of your own blood (autologous) is the safest method but requires planning ahead and not all patients are eligible. Directed donor blood allows the patient to receive blood from known donors. Volunteer donor blood is usually most readily available and, when properly tested has a low incidence of adverse events.
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Transplant: The grafting of a tissue from one place to another, just as in botany a bud from one plant might be grafted onto the stem of another. The transplanting of tissue can be from one part of the patient to another (autologous transplantation), as in the case of a skin graft using the patient's own skin; or from one patient to another (allogenic transplantation), as in the case of transplanting a donor kidney into a recipient.
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Tumor: An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be benign or malignant (cancerous). There are dozens of different types of tumors. Their names usually reflect the kind of tissue they arise in, and may also tell you something about their shape or how they grow. For example, a medulloblastoma is a tumor that arises from embryonic cells (a blastoma) in the inner part of the brain (the medulla). Diagnosis depends on the type and location of the tumor. Tumor marker tests and imaging may be used; some tumors can be seen (for example, tumors on the exterior of the skin) or felt (palpated with the hands).
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Uncertainty: You may be uncertain why "uncertainty" deserves a place in a medical dictionary but some would say that uncertainty is a key element in medicine.
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Urea: A nitrogen-containing substance normally cleared from the blood by the kidney into the urine . Diseases that compromise the function of the kidney often lead to increased blood levels of urea, as measured by the blood urea nitrogen ( BUN ) test.
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Urine: Liquid waste. The urine is a clear, transparent fluid. It normally has an amber color. The average amount of urine excreted in 24 hours is from 40 to 60 ounces (about 1,200 cubic centimeters). Chemically, the urine is mainly an aqueous (watery) solution of salt (sodium chloride) and substances called urea and uric acid. Normally, it contains about 960 parts of water to 40 parts of solid matter. Abnormally, it may contain sugar (in diabetes), albumen (a protein) (as in some forms of kidney disease), bile pigments (as in jaundice ), or abnormal quantities of one or another of its normal components.
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Vascular: Relating to the blood vessels of the body. The blood vessels of the body, as a group, are referred to as the vascular system.
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Vein: A blood vessel that carries blood low in oxygen content from the body back to the heart. The deoxygenated form of hemoglobin (deoxyhemoglobin) in venous blood makes it appear dark. Veins are part of the afferent wing of the circulatory system which returns blood to the heart.
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Vertebrae: The preferred plural of vertebra . (The alternate plural is vertebras.) See also: Cervical vertebrae ; Coccygeal vertebrae ; Lumbar vertebrae ; Sacral vertebrae ; and Thoracic vertebrae .
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Vertebroplasty: A nonsurgical method for the repair of vertebral fractures and compression due to osteoporosis .
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Vessel: A tube in the body that carries fluids: blood vessels or lymph vessels.
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Viral: Of or pertaining to a virus. For example, "My daughter has a viral rash ."
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Warfarin : An anticoagulant drug (brand names: Coumarin, Panwarfin, Sofarin) taken to prevent the blood from clotting and to treat blood clots and overly thick blood. Warfarin is also used to reduce the risk of clots causing strokes or heart attacks .
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WBC: Commonly used abbreviation for a white blood cell.
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Weight loss: Weight loss is a decrease in body weight resulting from either voluntary ( diet , exercise ) or involuntary (illness) circumstances. Most instances of weight loss arise due to the loss of body fat, but in cases of extreme or severe weight loss, protein and other substances in the body can also be depleted. Examples of involuntary weight loss include the weight loss associated with cancer , malabsorption (such as from chronic diarrheal illnesses ), and chronic inflammation (such as with rheumatoid arthritis ).
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White blood cell: One of the cells the body makes to help fight infections. There are several types of white blood cells ( leukocytes ). The two most common types are the lymphocytes and neutrophils (also called polymorphonuclear leukocytes, PMNs, or "polys").
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White blood cell count (leukocyte count): The number of white blood cells (WBCs) in the blood. The WBC is usually measured as part of the CBC ( complete blood count ). White blood cells are the infection-fighting cells in the blood and are distinct from the red (oxygen-carrying) blood cells known as erythrocytes. There are different types of white blood cells, including neutrophils (polymorphonuclear leukocytes ; PMNs), band cells (slightly immature neutrophils), T-type lymphocytes (T cells), B-type lymphocytes (B cells), monocytes, eosinophils, and basophils. All the types of white blood cells are reflected in the white blood cell count. The normal range for the white blood cell count varies between laboratories but is usually between 4,300 and 10,800 cells per cubic millimeter of blood. This can also be referred to as the leukocyte count and can be expressed in international units as 4.3 - 10.8 x 109 cells per liter.
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X-ray: 1. High-energy radiation with waves shorter than those of visible light. X-rays possess the properties of penetrating most substances (to varying extents), of acting on a photographic film or plate (permitting radiography), and of causing a fluorescent screen to give off light (permitting fluoroscopy). In low doses X-rays are used for making images that help to diagnose disease, and in high doses to treat cancer . Formerly called a Roentgen ray. 2. An image obtained by means of X-rays.
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