Nonsurgical Treatment of Erectile Dysfunction (cont.)
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Intraurethral Pellet Therapy
Intraurethral pellet therapy, also called the medicated urethral system for erections (MUSE), is a useful alternative for men who do not want to use self-injections or for men in whom oral medications have failed.
Alprostadil, a drug also discussed in Penile Injection Therapy, has been formulated into a small suppository. This suppository is inserted into the urethra (the canal through which urine and semen are excreted). Because of this, urinating immediately before use is important in order to moisten the passage.
A temporary tourniquet is often helpful in allowing the medication to stay in the erectile tissue a little longer and seems to give a somewhat better response.
Few side effects occur with intraurethral pellet therapy. The most common side effect is pain at the site where the pellet is deposited. A small amount of bleeding may also occur.
Stephen W Leslie, MD, FACS
Bradley Fields Schwartz, DO, FACS
Mary L Windle, PharmD
Martin I Resnick, MD
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