Font Size

Obsessive Compulsive Disorder (cont.)

Obsessive Compulsive Disorder Medications

  • The selective serotonin reuptake inhibitor (SSRI) group of medications is usually considered to be the most desirable treatment for OCD. This is also true for OCD symptoms that occur in the context of autism spectrum disorders. Examples of SSRI medications include sertraline (Zoloft), paroxetine (Paxil), and fluoxetine (Prozac). The possible side effects of this group of medications can vary greatly from person to person and depend on which medication is being used. Common side effects of SSRIs include dry mouth, sexual dysfunction, nausea, tremors, trouble sleeping, blurred vision, constipation or soft stools, and dizziness. For this group of medication, missing one or more doses may result in sufferers experiencing achiness, tiredness, or stomach upset.
  • Tricyclic antidepressants (TCAs) have also effectively treated OCD. Examples of TCAs are clomipramine (Anafranil), amitriptyline (Elavil), and imipramine (Tofranil). Many TCAs are less well tolerated than the SSRIs. In treatment-resistant cases, benzodiazepines may be used when the patient does not have a history of substance-abuse disorders. Examples of benzodiazepines include clonazepam (Klonopin), lorazepam (Ativan), and alprazolam (Xanax). In very rare cases, some people have been thought to become more acutely more anxious or depressed once on any antianxiety/antidepressant medication, even trying to or completing suicide or homicide. Although debate continues about whether the medication or the illness itself is the cause of this rare complication, it is thought to be more likely to occur in children and teens.

As about half of people who receive an adequate trial of SSRI medication fail to experience an adequate decrease in OCD symptoms, the use of other medications and psychotherapies is important. For people who do not respond robustly to the combination of psychotherapy and one medication, some OCD sufferers may improve with the addition of one of the following medications:

While certain subtypes of OCD may tend to respond more or less robustly to psychotherapy versus medication, there is enough variability in how individuals respond to treatment that either antipsychotic or antiseizure medication treatment is often considered in each person with OCD.

  • In treating postpartum OCD, time is of the essence during this critical time of maternal-infant bonding. Therefore, sometimes faster-acting medications like tramadol (Ultram) are used to treat this disorder. Tramadol is a pain reliever that increases the activity of serotonin, epinephrine, norepinephrine, and opiates that naturally occur in the brain and works rapidly. This is in contrast to medications like the SSRIs, which can take weeks to work.
Medically Reviewed by a Doctor on 6/23/2016

Must Read Articles Related to Obsessive Compulsive Disorder

Anxiety Anxiety as a medical condition is characterized b...learn more >>

Patient Comments & Reviews

The eMedicineHealth doctors ask about Obsessive Compulsive Disorder (OCD):

Obsessive Compulsive Disorder (OCD) - Describe Your Experience

Please describe your experience with obsessive compulsive disorder (OCD).

Obsessive Compulsive Disorder OCD - Symptoms

What symptoms did you experience with your obsessive compulsive disorder (OCD)?

Obsessive Compulsive Disorder - Treatment

What was the treatment for your obsessive compulsive disorder?

Medical Dictionary