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February 10, 2012
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Osteoarthritis (cont.)

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Osteoarthritis Medications

Initially, simple over-the-counter pain relievers such as acetaminophen are recommended, followed by NSAIDs. Prescription NSAIDs may be needed if the over-the-counter medications are ineffective. A new generation of prescription NSAIDs are the COX-2 medicines (celecoxib [Celebrex]). The COX-2 drugs have fewer reported gastrointestinal side effects but similar results compared to the typical NSAIDs.

The antidepressant duloxetine (Cymbalta) is now approved by the Food and Drug Administration (FDA) for chronic musculoskeletal pain (joint and muscle pain). This medication works on neurotransmitters in the brain that control pain perception and has been shown to decrease chronic low back pain and pain caused by knee osteoarthritis.

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Viewer Comments & Reviews

Osteoarthritis - Symptoms at Onset of Disease

The eMedicineHealth physician editors ask:

The symptoms of osteoarthritis can vary greatly from patient to patient. What were your symptoms at the onset of your disease?

Osteoarthritis - Treatment

The eMedicineHealth physician editors ask:

What was the treatment for your osteoarthritis?

Arthritis

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Read What Your Physician is Reading on Medscape

Osteoarthritis »

Osteoarthritis (OA) is the most common articular disease worldwide, affecting over 20 million individuals in the United States alone.

Read More on Medscape Reference »

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