Paget's Disease Glossary of Terms

The following are health and medical definitions of terms that appear in the Paget's Disease article.

Abnormal: Outside the expected norm, or uncharacteristic of a particular patient.

Absorption: Uptake. For example, intestinal absorption is the uptake of food (or other sub...

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Alkaline phosphatase: An enzyme that liberates phosphate under alkaline conditions and is ...

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Arthritis: Inflammation of a joint. When joints are inflamed they can develop stiffness, w...

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Autosomal: Pertaining to a chromosome that is not a sex chromosome. People normally have 2...

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Autosomal dominant: A pattern of inheritance in which an affected individual has one copy ...

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Back pain: Pain felt in the low or upper back. Causes of pain in the low and upper back in...

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Biopsy: The removal of a sample of tissue for examination under a microscope to check for ...

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Bisphosphonate: A class of drugs used to strengthen bone. Bisphosphonates are used to trea...

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Bladder: A hollow organ in the lower abdomen that stores urine. The kidneys filter waste f...

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Bowel: The small and large intestine.

Calcitonin: A hormone produced by the thyroid gland that lowers the levels of calcium and ...

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Calcium: A mineral found mainly in the hard part of bones, where it is stored. Calcium is ...

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Compression: 1. The act of pressing together. As in a compression fracture, nerve c...

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Congestive heart failure: Inability of the heart to keep up with the demands on it, with f...

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CT scan: Computed tomography scan. Detailed images of internal organs are obtained by this...

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Deafness: Partial or complete hearing loss. Levels of hearing impairment vary from a mild ...

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Decompression: 1. In general, the removal of pressure.
2. In surgery, ...

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Degenerative joint disease: Also known as osteoarthritis, this type of arthritis is cause...

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Diagnosis: 1 The nature of a disease; the identification of an illness. 2 A ...

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Dysfunction: Difficult function or abnormal function.

Ear: The hearing organ. There are three sections of the ear, according to the anatomy tex...

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Erosion: An erosion is an eating away of a surface. ("Erodere" in Latin means to eat out.)...

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Esophagus: The tube that connects the pharynx (throat) with the stomach. The esophagus lie...

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Fracture: A break in bone or cartilage. Although usually a result of trauma, a fracture ca...

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Genetic: Having to do with genes and genetic
information.

Heart: The muscle that pumps blood received from veins into arteries throughout the body. ...

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Heart failure: Inability of the heart to keep up with the demands on it and, specifically...

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Hormone: A chemical substance produced in the body that controls and regulates the activit...

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Human parainfluenza virus: One in a group of four RNA viruses that rank second only to re...

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Ibuprofen: A nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to treat pa...

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Inheritance: The transmission of a gene from parent to child. The pattern of inheritance i...

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Inner ear: A highly complex structure whose essential component for hearing is the membran...

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Joint: The area where two bones are attached for the purpose of permitting body parts to m...

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Kidney: One of a pair of organs located in the right and left side of the abdomen. The kid...

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Knee: The knee is a joint which has three parts. The thigh bone (the femur) meets the lar...

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Laboratory: A place for doing tests and research procedures, and for preparing chemicals a...

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Low back pain: Pain in the lower back area that can relate to problems with the lumbar spi...

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Magnetic resonance imaging: A procedure that uses magnetism, radio waves, and a computer t...

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Malignancy: A tumor that is malignant (cancerous), that can invade and destroy nearby tiss...

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Malignant: 1. Tending to be severe and become progressively worse, as in malignant ...

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Measles: An acute and highly contagious viral disease characterized by fever, runny nose,...

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MRI: Magnetic resonance imaging.

Muscle: Muscle is the tissue of the body which primarily functions as a source of power. T...

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Nerve: A bundle of fibers that uses electrical and chemical signals to transmit sensory an...

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Osteitis: Inflammation of the bone.

Osteitis deformans: Better known today as Paget disease, this is a chronic bone disorder t...

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Osteoporosis: Thinning of the bones, with reduction in bone mass, due to depletion of calc...

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Pagetic: Pertaining to Paget disease, a chronic disorder that typically results in enlarge...

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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pa...

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Parainfluenza: A disease due to an acute respiratory infection caused by a parainfluenza v...

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Paramyxovirus: One of a group of RNA viruses that are predominantly responsible for acute ...

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Parathyroid hormone: See Parathormone.

Pathologic: 1. Indicative of or caused by disease, as in a pathologic fracture, pat...

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Phosphate: A form of phosphoric acid. Calcium phosphate makes bones and teeth hard.

Physical therapy: A branch of rehabilitative health that uses specially designed exercises...

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Procollagen: A precursor (forerunner) of collagen, the protein that adds strength and supp...

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Prognosis: The forecast of the probable outcome or course of a disease; the patient's chan...

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Resorption: The process of losing substance. For example, when bone is surgically reshaped...

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Respiratory: Having to do with respiration.

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Respiratory syncytial virus: A virus that causes mild respiratory infections, colds, and c...

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Sarcoma: One of a group of tumors usually arising from connective tissue. Most sarcomas ar...

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Scan: As a noun, the data or image obtained from the examination of organs or regions of...

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Sclerosis: Localized hardening of skin. Sclerosis is generally caused by underlying diseas...

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Serum: The clear liquid that can be separated from clotted blood. Serum differs from plas...

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Skull: The skull is a collection of bones which encase the brain and give form to the hea...

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Spinal cord: The major column of nerve tissue that is connected to the brain and lies with...

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Spinal stenosis: Narrowing of the spinal canal. Spinal stenosis is most commonly caused by...

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Spine: 1) The column of bone known as the vertebral column, which surrounds and protects ...

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Stenosis: A narrowing. For example, aortic stenosis is a narrowing of the aortic valve in ...

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Surgery: The branch of medicine that employs operations in the treatment of disease or inj...

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Symptom: Any subjective evidence of disease. In contrast, a sign is objective. Blood comin...

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Therapy: The treatment of disease. Therapy is synonymous with treatment.

Tumor: An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be ...

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Urinary: Having to do with the function or anatomy of the kidneys, ureters, bladder, or ur...

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Urine: Liquid waste produced by the kidneys. Urine is a clear, transparent fluid that norm...

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Viral: Of or pertaining to a virus. For example, if a person has a viral rash, the rash wa...

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Virus: A microorganism that is smaller than a bacterium that cannot grow or reproduce apar...

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X-ray: High-energy radiation with waves shorter than those of visible light. X-ray is used...

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