Pancoast tumors are tumors that form at the extreme apex (very top) of either the right or left lung in the superior sulcus (a shallow furrow on the surface of the lung). Pancoast tumors are a subset of lung cancers that invade the top of the chest wall. Because of their location in the apex of the lung, they invade adjoining tissue.
Pancoast tumors originate at the top margin of the lung. They form an abnormal patch of tissue over the lung apex and principally involve the chest wall structures rather than the underlying lung tissue. They invade the following structures:
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In 1932, Pancoast defined a superior pulmonary sulcus tumor as a mass growing at the thoracic inlet that produces a constant and characteristic clinical presentation of pain in an eighth cervical or first and second thoracic trunk distribution.
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