Pangamic Acid

Are there any interactions with medications?

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Digoxin (Lanoxin)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Digoxin (Lanoxin) helps the heart beat more strongly. Some types of pangamic acid contain calcium. Calcium might also affect the heart. Taking pangamic acid along with digoxin (Lanoxin) might increase the effects and side effects of digoxin (Lanoxin).

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Medications for high blood pressure (Calcium channel blockers)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Some medications for high blood pressure affect calcium in the body. These medications are called calcium channel blockers. Taking pangamic acid that contains calcium might decrease the effectiveness of these medications for high blood pressure.

Some medications for high blood pressure include nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), and others.

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Water pills (Thiazide diuretics)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Some pangamic acid can contain calcium. Some "water pills" increase the amount of calcium in the body. Taking large amounts of calcium with some "water pills" might cause there to be too much calcium in the body. This could cause serious side effects including kidney problems.

Some of these "water pills" include chlorothiazide (Diuril), hydrochlorothiazide (HydroDIURIL, Esidrix), indapamide (Lozol), metolazone (Zaroxolyn), and chlorthalidone (Hygroton).

Dosing considerations for Pangamic Acid.

The appropriate dose of pangamic acid depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for pangamic acid. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.