Parkinson Disease Dementia (cont.)
IN THIS ARTICLE
Parkinson's Disease Dementia Surgery and Gene Therapy
Great strides have been made in surgical treatment of Parkinson's disease. Several different procedures are now available, and they are successful in many patients in relieving movement symptoms. Unfortunately, surgery has no effect on cognitive symptoms. In fact, most people with dementia are not candidates for surgery.
Gene therapy is in its infancy; there are ongoing human and animal trials with various methods (liposomes, viruses) to insert genes into neuronal cells to reduce or stop Parkinson's disease symptoms by causing cells to produce dopamine coded by the newly inserted genes. Early results with the treatment termed ProSavin (modified virus insertion) are encouraging. I However, it is not clear if such therapy could prevent or reverse Parkinson's disease dementia.
Medically Reviewed by a Doctor on 4/30/2014
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