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Peptic Ulcers

Peptic Ulcers Overview

In the digestive system, an ulcer is an area where tissue has been destroyed by gastric juices and stomach acid. Peptic ulcer disease is a general term for ulcers that occur in the stomach or duodenum (upper part of the small intestine).

  • A peptic ulcer is an erosion or sore in the wall of the gastrointestinal tract.

  • The mucous membrane lining the digestive tract erodes and causes a gradual breakdown of tissue.

  • This breakdown causes a gnawing or burning pain in the upper middle part of the belly (abdomen).

  • Although most peptic ulcers are small, they can cause a considerable amount of discomfort.

Peptic ulcers are a very common condition in the United States and throughout the world.

  • In the United States, an estimated 25 million people will suffer an ulcer at some point. That's 1 in 10 people.

  • About 4 million people are affected by ulcers at any given time.

  • There are approximately 350,000-500,000 new cases and more than 1 million ulcer-related hospitalizations each year in this country alone.

  • About 6000 people die each year of ulcer-related complications.

Ulcers can occur at any age, although they are rare in children and teenagers.

  • Duodenal ulcers usually first occur between the ages of 30-50 years and are twice as common in men as in women.

  • Stomach (or gastric) ulcers usually occur in people older than 60 years and are more common in women.

The good news is that we have learned a lot about ulcers in the past 20 years and effective therapies are now available.



Next: Peptic Ulcers Causes »

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Peptic Ulcers - Symptoms At Onset Of Disease

The eMedicineHealth physician editors ask:

The symptoms of peptic ulcers can vary greatly from patient to patient. What were your symptoms at the onset of your disease?

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Peptic Ulcer Disease »

Peptic ulcer disease (PUD) is a common disorder that affects millions of individuals in the United States each year. 

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