Phosphatidylserine

Are there any interactions with medications?

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Drying medications (Anticholinergic drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Some drying medications are called anticholinergic drugs. Phosphatidylserine might increase chemicals that can decrease the effects of these drying medications.

Some drying medications include atropine, scopolamine, and some medications used for allergies (antihistamines) and for depression (antidepressants).

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Medications for Alzheimer's disease (Acetylcholinesterase (AChE) inhibitors)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Phosphatidylserine might increase a chemical in the body called acetylcholine. Medications for Alzheimer's disease called acetylcholinesterase inhibitors also increase the chemical acetylcholine. Taking phosphatidylserine along with medications for Alzheimer's disease might increase effects and side effects of medications for Alzheimer's disease.

Some acetylcholinesterase medications include donepezil (Aricept), tacrine (Cognex), rivastigmine (Exelon), and galantamine (Reminyl, Razadyne).

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Various medications used for glaucoma, Alzheimer's disease, and other conditions (Cholinergic drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Phosphatidylserine might increase a chemical in the body called acetylcholine. This chemical is similar to some medications used for glaucoma, Alzheimer's disease, and other conditions. Taking phosphatidylserine with these medications might increase the chance of side effects.

Some of these medications used for glaucoma, Alzheimer's disease, and other conditions include pilocarpine (Pilocar and others) and others.

Dosing considerations for Phosphatidylserine.

The following doses have been studied in scientific research:

BY MOUTH:

• For Alzheimer's disease, and other age-related thinking or memory impairment: 100 mg of phosphatidylserine three times daily.