Medications

Medicine for preeclampsia and high blood pressure during pregnancy may be used to:

• Control high blood pressure. Lowering high blood pressure does not prevent preeclampsia from getting worse, because high blood pressure is only a symptom of the condition, not a cause. Your doctor may recommend blood pressure medicine if your blood pressure reaches high levels. Expectant management is often used to treat mild high blood pressure during pregnancy.
• Prevent seizures. Magnesium sulfate is usually started before delivery and continued for 24 hours after delivery for women with pregnancy-related seizures (eclampsia) and those who have moderate to severe preeclampsia.
• Speed up fetal lung development. When possible, a corticosteroid (betamethasone or dexamethasone) is given to the mother prior to a premature birth (up to 34 weeks of gestation). This medicine matures the fetus's lungs over a 24-hour period, which lowers the risk of breathing problems after birth.

Medication Choices

Blood pressure medicines commonly used during pregnancy include:

• Methyldopa (an oral medicine for controlling high blood pressure during pregnancy).
• Hydralazine (an intravenous medicine for quickly lowering severely high blood pressure during pregnancy).
• Labetalol (an intravenous medicine for quickly lowering severely high blood pressure in the hospital, and also an oral medicine for controlling high blood pressure during pregnancy).
• Nifedipine (an oral medicine for controlling high blood pressure during pregnancy).

Magnesium sulfate is the most common medicine used for preventing eclampsia (seizures) during pregnancy.

Steroid medicines such as betamethasone and dexamethasone may be used to help the fetus's lungs mature faster. These medicines are often given if preterm delivery is needed.

What To Think About

There is not enough medical evidence to show which blood pressure medicine is most effective for use during pregnancy.

Some high blood pressure medicines are dangerous during pregnancy.⁶ If you take high blood pressure medicines, talk to your doctor about the safety of your medicine before you become pregnant or as soon as you learn you are pregnant. Make sure that your doctor has a complete list of all medicines that you are taking.

Lowering blood pressure too much or too fast can reduce blood flow to the placenta, causing problems for the fetus. So medicine is reserved for preventing severely high blood pressure levels that may be life-threatening to you or your fetus.