Pregnenolone

Are there any interactions with medications?

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Estrogens
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Pregnenolone is used in the body to make hormones including estrogen. Taking estrogen along with pregnenolone might cause too much estrogen to be in the body.

Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.

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Progestin
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Progestins are a group of hormones. Taking other hormones along with progesterone pills might cause too much hormones in the body. This could increase the effects and side effects of hormone pills.

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Testosterone
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

The body changes pregnenolone into testosterone. Taking pregnenolone along with a testosterone pill might cause too much testosterone in the body. This might increase the chance of testosterone side effects.

Dosing considerations for Pregnenolone.

The appropriate dose of pregnenolone depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for pregnenolone. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.