Vitamin B6 — 100 mg per day maximum (larger doses sometimes cause serious side effects). You can also take a B-complex that includes all the B vitamins. Vitamin B6 may take the edge off irritability and reduce fatigue and depression.
Vitamin E — 400 IU per day (maximum) may be helpful in reducing breast tenderness.
Calcium — 1,000-1,200 mg per day of elemental calcium (the labels on foods and supplements give the amount of elemental calcium they contain) may reduce bloating, body aches, anxiety, or depression.
Magnesium — 400 mg per day in combination with vitamin B6 may reduce pain, water retention, and negative mood.
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