Primary Insomnia (cont.)
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What medications treat symptoms and cure primary insomnia?
Treatment with medicine usually provides rapid symptomatic relief.
The mainstays of short-term treatment of primary insomnia include: hypnotics (agents that promote sleep) and benzodiazepines (compounds with antianxiety, hypnotic, anticonvulsant, and muscle relaxant properties).
Hypnotics for primary insomnia
Basic principles for the treatment of insomnia include the following:
*Zolpidem and Zaleplon are not structurally related to benzodiazepines.
Common side effects of hypnotics are as follows:
Not everyone should take hypnotic medications. Contraindications of hypnotics are as follows:
Caution and close monitoring is needed in older people and in persons with hepatic, renal, or pulmonary disease.
Belsomra (suvorexant) is an orexin antagonist, a newer classification of insomnia medication. Orexion antagonists work by decreasing activity in the wake center of the brain and helping individuals transition to sleep. The other hypnotic medications typically act on the sleep promoting centers of the brain by attempting to increase activity in these areas. Dosage for Belsomra is 5 to 20 mg/2 hr. Belsomra is completely unrelated to both the benzodiazepine and non-benzodiazepine sedative-hypnotic drugs.
Medically Reviewed by a Doctor on 8/26/2016
Aparna Ranjan, MD
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