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Treatment of proctitis depends on the cause of the disease.

• Because the most common cause of proctitis remains sexually transmitted disease, you may be given antibiotics to kill the organism. The presence of one type of infection also suggests the presence of other types of sexually transmitted diseases, so antibiotic treatment may be directed at 2 or more infectious organisms at the same time. Some of the medications can be given in a single injection.
• You must use safe sex practices, such as condoms, if you engage in high-risk sexual behavior.
• If you have inflammatory disease causing proctitis, such as ulcerative colitis or Crohn disease, you will require continuing treatment. Treatments include medications that suppress the immune system, such as steroids. Your doctor may prescribe steroid suppositories to provide relief in your rectum. In addition you may receive treatment for control of symptoms such as diarrhea.

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