Important
It is possible that the main title of the report Progressive Supranuclear Palsy is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

• PSP
• nuchal dystonia dementia syndrome
• Steele-Richardson-Olszewski syndrome

Disorder Subdivisions

• None

General Discussion

Progressive supranuclear palsy (PSP) is a rare degenerative neurological disorder characterized by loss of balance and impaired walking; loss of control of voluntary eye movement, especially in the downward direction; abnormal muscle tone (rigidity); speech difficulties (dysarthria); and problems related to swallowing and eating (dysphagia). Affected individuals frequently experience personality changes and cognitive impairment. Symptoms typically begin after age 60 but can begin earlier. The exact cause of progressive supranuclear palsy is unknown. PSP is often misdiagnosed as Parkinson disease, Alzheimer disease, or other neurodegenerative disorders.

Resources

WE MOVE (Worldwide Education and Awareness for Movement Disorders)
5731 Mosholu Avenue
Bronx, NY 10471
USA
Tel: (347)843-6132
Fax: (718)601-5112
Email: wemove@wemove.org
Internet: http://www.wemove.org

CurePSP: Foundation for PSP l CBD & Related Brain Diseases
30 E. Padonia Road, Suite 201
Timonium, MD 21093
Tel: (410)785-7004
Fax: (410)785-7009
Tel: (800)457-4777
Email: info@curepsp.org
Internet: http://www.curepsp.org

NIH/National Institute of Neurological Disorders and Stroke
P.O. Box 5801
Bethesda, MD 20824
Tel: (301)496-5751
Fax: (301)402-2186
Tel: (800)352-9424
TDD: (301)468-5981
Email: me20t@nih.gov
Internet: http://www.ninds.nih.gov/

Progressive Supranuclear Palsy Association UK
PSP House
167 Watling Street West
Towcester
Northamptonshire, Intl NN12 6BX
United Kingdom
Tel: 01327 322410
Fax: 01327 322412
Email: psp@pspeur.org
Internet: http://www.pspeur.org/

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Internet: http://rarediseases.info.nih.gov/GARD/

National Parkinson Foundation, Inc.
1501 NW 9th Ave/Bob Hope Road
Miami, FL 33136-1494
Tel: (305)243-6666
Fax: (305)243-6073
Tel: (800)327-4545
Email: contact@parkinson.org
Internet: http://www.parkinson.org

UCSF Memory and Aging Center
350 Parnassus Avenue
Suite 905
San Francisco, CA 94117
Tel: (415)476-6880
Fax: (415)476-4800
Email: mgeschwind@memory.ucsf.edu
Internet: http://www.memory.ucsf.edu

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated: 4/19/2011
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