Prostate Cancer (cont.)
IN THIS ARTICLE
Prostate cells are physiologically dependent on male hormones called androgens. Androgens cause hormonal stimulation of the prostate cancer cells causing them to grow, function, and proliferate. Testosterone, although not directly carcinogenic, is essential for the growth and perpetuation of tumor cells. The testes are the source of most androgens. The goal of hormonal therapy is to lower levels of testosterone or to stop testosterone from working. This can be achieved with surgery or with drug treatment. Often, the initial response is good, but cancer may progress over time.
Androgen deprivation therapy: This therapy is likely to be used in cases in which the cancer has spread to distant regions. Therefore, it is not currently used among the standard options for men with localized prostate disease. It may be added to surgery and radiation in cases at high risk for relapse due to high Gleason score and/or positive surgical margins.
Medically Reviewed by a Doctor on 3/31/2015
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Prostate cancer is the most common noncutaneous cancer among males.