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Pulmonary Hypertension (cont.)

Medication

In patients with primary pulmonary hypertension, several specific medications are available. The action of these drugs is complicated, but in general they work by opening up (dilate) the pulmonary arteries to facilitate blood flow by reducing the resistance against it.

Some of the commonly used drugs for the treatment of primary pulmonary hypertension include:

  • prostacyclin (Epoprostenol, Flolan),
  • bosentan (Tracleer),
  • intravenous treprostinil (Remodulin),
  • inhaled iloprost (Ventavis),
  • sildenafil (Viagra, Revatio),
  • calcium channel blockers [such as nifedipine ()Adalat, Adalat CC, Procardia, Procardia XL)],
  • sitaxsentan (Thelin) - not FDA approved in the U.S, and
  • ambrisentan (Letairis).

At times, these medications can also be used in cases of secondary pulmonary hypertension if it is severe or not well controlled despite adequate management of the underlying condition.

Medically Reviewed by a Doctor on 6/24/2014

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