Font Size

Pustular Psoriasis (cont.)

Pustular Psoriasis Causes

To best understand the causes of pustular psoriasis, one must know the causes of classical plaque-type psoriasis. It is generally agreed that a combination of genetics and environment induce psoriasis, including this pustular subtype. Below is a list of factors that are known to be associated with pustular psoriasis:

  • Taking systemic steroids (steroid medications given by mouth or by injection) and then discontinuing them
  • Taking various medications, including the following
    • Salicylates, compounds made from salicylic acid, often used to treat pain and fever
    • Oral iodides (SSKI)
    • Lithium or trazodone, antidepressants
    • Phenylbutazone or oxyphenbutazone, nonsteroidal anti-inflammatory drugs (NSAIDs)
    • Penicillin, an antibiotic
    • Hydroxychloroquine, an antimalarial drug
    • Calcipotriol, a vitamin-D derivative
    • Interferon alfa and recombinant interferon-beta injections, chemotherapeutic agents
    • TNF-blocking biologic medications, such as infliximab (Remicade)
  • Strong, irritating topical solutions (creams or ointments applied to the skin), including tar, anthralin, steroids under occlusion, and zinc pyrithione in shampoo
  • Infections
  • Pregnancy
  • Sunlight or phototherapy
  • Cholestatic jaundice (a yellowish staining of the skin and eyes, caused by bile)
  • Hypocalcemia (abnormally low levels of calcium in the blood)

In many people, the trigger is never identified.

Medically Reviewed by a Doctor on 5/8/2014

Must Read Articles Related to Pustular Psoriasis

Psoriasis Psoriasis is a common and chronic skin disorder that affects 1%-2% of people in the U.S. Symptoms and signs include red, raised, scaly areas on the skin that ma...learn more >>
Psoriatic Arthritis
Psoriatic Arthritis Psoriatic arthritis is a specific condition autoimmune condition in which a person has both psoriasis and arthritis. Some psoriatic arthritis symptoms and signs...learn more >>
Types of Psoriasis
Types of Psoriasis Psoriasis is a chronic disease of the skin that affects approximately 5.5 million people in the United States. Typical characteristics of psoriasis are red, dry...learn more >>

Patient Comments & Reviews

The eMedicineHealth doctors ask about Pustular Psoriasis:

Pustular Psoriasis - Symptoms

What were your symptoms of pustular psoriasis?

Read What Your Physician is Reading on Medscape

Psoriasis, Pustular »

Pustular psoriasis is an uncommon form of psoriasis consisting of widespread pustules on an erythematous background

Read More on Medscape Reference »

Medical Dictionary