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Raynaud Phenomenon (cont.)

Raynaud Phenomenon Causes

The classification of Raynaud phenomenon is usually separated in two categories: idiopathic or primary Raynaud, when no associated disease is identified; and secondary to other diseases.

  • Factors that can bring on Raynaud phenomenon (all vasoconstrictive influences), include the following:

    • Cold environments

    • Mental stressors

    • Certain occupations (vibration from tools, like jackhammers)

    • Smoking (nicotine is a stimulant/vasoconstrictor)

  • Diseases causing Raynaud phenomenon

    • Collagen vascular diseases - Seventy percent of patients with scleroderma (or those who have systemic sclerosis) develop Raynaud phenomenon. Other disorders including systemic lupus erythematosus, rheumatoid arthritis, or dermatomyositis/polymyositis are also associated with a high incidence of Raynaud phenomenon.

    • Arterial diseases, including atherosclerosis, plus thromboangiitis obliterans or Buerger disease involving the small arteries and veins of the hands and feet, also have an association with Raynaud phenomenon. 

    • Neurologic disorders - Thoracic outlet syndrome with compression of nerves as they course through the neck and shoulder area; carpal tunnel syndrome; and occasionally stroke, intervertebral disk disease, and spinal cord tumors may produce Raynaud phenomenon

    • Blood disorders that cause the blood to thicken or sludge (polycythemia)

    • Trauma

    • Miscellaneous disorders such as hypothyroidism

  • Medications that may cause or worsen Raynaud phenomenon

    • These include ergot derivatives, used for migraine headaches (ergotamine), beta-adrenergic blockers, amphetamines or other drugs that constrict (make the blood vessels smaller), and some chemotherapeutic agents (vinblastine, bleomycin)



Next: Raynaud Phenomenon Symptoms »

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Raynaud Phenomenon »

Raynaud phenomenon refers to reversible ischemia of peripheral arterioles.

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