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February 10, 2012
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Raynaud Phenomenon (cont.)

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Raynaud's Phenomenon Causes

The classification of Raynaud's phenomenon is usually separated in two categories: idiopathic or primary Raynaud's, when no associated disease is identified; and secondary to other diseases.

  • Factors that can bring on Raynaud's phenomenon (all vasoconstrictive influences), include the following:

    • Cold environments

    • Mental stressors

    • Certain occupations (vibration from tools, like jackhammers)

    • Smoking (nicotine is a stimulant/vasoconstrictor)

  • Diseases causing Raynaud's phenomenon

    • Collagen vascular diseases - Seventy percent of patients with scleroderma (or those who have systemic sclerosis) develop Raynaud's phenomenon. Other disorders including systemic lupus erythematosus, rheumatoid arthritis, or dermatomyositis/polymyositis are also associated with a high incidence of Raynaud's phenomenon.

    • Arterial diseases, including atherosclerosis, plus thromboangiitis obliterans or Buerger disease involving the small arteries and veins of the hands and feet, also have an association with Raynaud's phenomenon. 

    • Neurologic disorders - Thoracic outlet syndrome with compression of nerves as they course through the neck and shoulder area; carpal tunnel syndrome; and occasionally stroke, intervertebral disk disease, and spinal cord tumors may produce Raynaud's phenomenon

    • Blood disorders that cause the blood to thicken or sludge (polycythemia)

    • Trauma

    • Miscellaneous disorders such as hypothyroidism

  • Medications that may cause or worsen Raynaud's phenomenon

    • These include ergot derivatives, used for migraine headaches (ergotamine), beta-adrenergic blockers, amphetamines or other drugs that constrict (make the blood vessels smaller), and some chemotherapeutic agents (vinblastine, bleomycin)

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Read What Your Physician is Reading on Medscape

Raynaud Phenomenon »

Raynaud phenomenon refers to reversible ischemia of peripheral arterioles.

Read More on Medscape Reference »

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