1. Causes of Fatigue Slideshow Pictures
2. Take the Sleep Quiz!
3. Foods That Help or Harm Your Sleep Slideshow Pictures

The exact cause ofREM sleep behavior disorder(RBD) is unknown, although the disorder may occur in association with various degenerative neurological conditionssuch as Parkinson disease, multisystem atrophy, diffuse Lewy body dementia,and Shy-Drager syndrome. In 55% of persons the cause is unknown, and in 45%, the cause is associated with alcohol or sedative-hypnotic withdrawal, tricyclic antidepressant (such as imipramine), or serotonin reuptake inhibitor use (such as fluoxetine,sertraline, orparoxetine)or other types of antidepressants (mirtazapine).

RBD often precedes the development ofthese neurodegenerative diseases by several years. In one study, 38% of patients diagnosed withRBDsubsequently developed Parkinson disease within an average time of 12-13 years from the onset ofRBDsymptoms. The prevalence of RBD is increased in persons with Parkinson disease and in multisystem atrophy where it is observed in 69% of these patients. The relationship betweenRBDand Parkinson disease is complex; however, not all persons with RBD develop Parkinson disease.

Must Read Articles Related to REM Sleep Behavior Disorder

Disorders That Disrupt Sleep (Parasomnias) Parasomnias are disruptive sleep-related disorders. They are characterized by undesirable physical or verbal behaviors or experiences. Parasomnias occur in asso...learn more >>

See the Entire REM Sleep Behavior Disorder Topic Guide »