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Renal Cell Cancer (cont.)

What Are Causes and Risk Factors of Renal Cell Carcinoma?

The exact cause of renal cell cancer has not been determined. A number of different factors seem to contribute to renal cell cancer. These risk factors include the following:

  • Cigarette smoking doubles the risk of renal cell cancer and contributes to as many as one third of all cases. The more someone smokes, the greater the risk is of that person developing renal cell cancer.
  • Obesity is a risk factor. As body weight increases, so does the risk of developing renal cell cancer. This is especially true in women.
  • Occupational exposure to petroleum products, heavy metals, solvents, coke-oven emissions, or asbestos
  • Cystic kidney disease associated with chronic (long-term) renal insufficiency
  • Cystic changes in the kidney and renal dialysis
  • Tuberous sclerosis
  • Von Hippel-Lindau (VHL) disease, an inherited disease associated with several cancers
  • Hereditary renal cancer
  • Associated malignancy such as lymphoma
Medically Reviewed by a Doctor on 12/14/2015
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Patient Comments & Reviews

The eMedicineHealth doctors ask about Renal Cell Cancer:

Renal Cell Carcinoma - Metastasis

Had your renal cell carcinoma metastasized by the time it was diagnosed?

Renal Cell Carcinoma - Treatment

What treatment has been effective for your renal cell carcinoma?

Renal Cell Carcinoma - Symptoms and Signs

The symptoms and signs of renal cell carcinoma can vary greatly from patient to patient. What were your symptoms and signs at the onset of your disease?


Read What Your Physician is Reading on Medscape

Renal Cell Carcinoma »

Renal cell carcinoma accounts for approximately 3% of adult malignancies and 90-95% of neoplasms arising from the kidney.

Read More on Medscape Reference »


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