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May 20, 2013
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Rhabdomyolysis (cont.)

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Rhabdomyolysis Medications

The goal of treatment to prevent kidney damage is to maximize the amount of fluid flowing through the nephrons and glomeruli in the kidney, in effect, trying to wash out the myoglobin fibers that can clog the filters of the kidney. The effect is to increase urine output, which can be measured and monitored.

  • Diuretic medications, such as furosemide (Lasix) may be given intravenously to promote urine output. This may be used even if the patient is somewhat dehydrated, but close observation of the patient's vital signs, including blood pressure and pulse rate, is necessary.

  • If the vital signs are stable, mannitol may also be injected intravenously to increase blood flow to the kidney and increase urine output.

  • Sodium bicarbonate may be added to the intravenous saline solution to change the acid-base balance of the urine.

  • Muscle injury may be extremely painful, and narcotic pain medications may be needed to control symptoms.

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