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Sarcoidosis is a disease that features a specific type of inflammation of various tissues of the body. Sarcoidosis can appear in almost any body organ, but it starts most often in the lungs or lymph nodes. As sarcoidosis progresses, microscopic lumps of a specific form of inflammation, called granulomas, appear in the affected tissues. In the majority of cases, these granulomas clear up, either with or without treatment. In the few cases in which the granulomas do not heal and disappear, the tissues involved tend to remain inflamed and become scarred (fibrotic). In addition to the lungs and lymph nodes, the organs more likely than others to be affected by sarcoidosis are the liver, skin, heart, nervous system, and kidneys, in that order of frequency.
Sarcoidosis is sometimes named according to the organ involved.
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