Sciatica Glossary of Medical Terms

These are medical definitions of medical terms from the MedTerms.com medical dictionary that appear in the Sciatica article.

Abscess: A local accumulation of pus anywhere in the body. The following are some examples of abscesses:

A skin abscess is better known as a common boil;
A peritonsillar abscess is a persistent collection of pus behind the tonsils ; and
A perianal abscess is a pool of pus that forms next to the anus , often causing considerable tenderness and swelling in that area and pain on sitting down and on defecating.

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Acetaminophen: A pain reliever and fever reducer. Brand name: Tylenol. The exact mechanism of action of acetaminophen is not known. Acetaminophen relieves pain by elevating the pain threshold (that is, by requiring a greater amount of pain to develop before it is felt by a person). Acetaminophen reduces fever through its action on the heat-regulating center (the "thermostat") of the brain. Generic is available.
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Acupuncture: The practice of inserting needles into the body to reduce pain or induce anesthesia . More broadly, acupuncture is a family of procedures involving the stimulation of anatomical locations on or in the skin by a variety of techniques. There are a number of different approaches to diagnosis and treatment in American acupuncture that incorporate medical traditions from China, Japan, Korea, and other countries. The most thoroughly studied mechanism of stimulation of acupuncture points employs penetration of the skin by thin, solid, metallic needles, which are manipulated manually or by electrical stimulation.
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Aging: The process of becoming older, a process that is genetically determined and environmentally modulated.
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Anemia: The condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen-carrying capacity of the blood is, therefore, decreased.
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Arthritis: Inflammation of a joint. When joints are inflamed they can develop stiffness, warmth, swelling, redness and pain. There are over 100 types of arthritis . (see osteoarthritis , rheumatoid arthritis , ankylosing spondylitis , psoriatic arthritis , lupus , gout , pseudogout ).
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Aspirin: A good example of a tradename that entered into the language, Aspirin was once the Bayer trademark for acetylsalicylic acid .
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Back pain: Pain felt in the low or upper back. There are many causes of back pain.
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Backbone: The spine. A flexible row of bones stretching from the base of the skull to the tailbone.
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Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Bladder: Any pouch or other flexible enclosure that can hold liquids or gases but usually refers to the hollow organ in the lower abdomen that stores urine -- the urinary bladder. The kidneys filter waste from the blood and produce urine, which enters the bladder through two tubes called ureters. Urine leaves the bladder through another tube, the urethra . In women, the urethra is a short tube that opens just in front of the vagina . In men, it is longer, passing through the prostate gland and then the penis . Infection of the bladder is called cystitis .
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Blood: The familiar red fluid in the body that contains white and red blood cells , platelets , proteins , and other elements. The blood is transported throughout the body by the circulatory system . Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.
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Blood clot: Blood that has been converted from a liquid to a solid state. Also called a thrombus .
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Blood count: The calculated number of white or red blood cells (WBCs or RBCs) in a cubic millimeter of blood.
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Blood in the urine: Blood in the urine is termed hematuria.
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Boil: A skin abscess , a collection of pus localized deep in the skin. A boil usually starts as a reddened, tender area and in time becomes firm and hard. Eventually, the center of the abscess softens and becomes filled with white blood cells that the body sends to fight the infection. This collection of white cells is the pus.
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Bone: Bone is the substance that forms the skeleton of the body. It is composed chiefly of calcium phosphate and calcium carbonate . It also serves as a storage area for calcium, playing a large role in calcium balance in the blood.
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Bone scan: A technique to create images of bones on a computer screen or on film. A small amount of radioactive material is injected and travels through the bloodstream. It collects in the bones, especially in abnormal areas of the bones, and is detected by special instrument called a scanner. The image of the bones is recorded on a special film for permanent viewing.
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Botox : A highly purified preparation of botulinum toxin A, a toxin produced by the bacterium Clostridium botulinum. Botox is for injection, in very small amounts, into specific muscles. It acts by blocking the transmission of nerve impulses to muscles and so paralyzing the muscles. Botox is a brand name that has passed into popular usage as a synonym for Botulinum toxin.
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Botulinum toxin: A toxin produced by the bacterium Clostridium botulinum that is the most poisonous biological substance known. Botulinum toxin acts as a neurotoxin . It binds to the nerve ending at the point where the nerve joins a muscle, blocking the release by the nerve of the chemical acetylcholine (the principal neurotransmitter at the neuromuscular junction), preventing the muscle from contracting. The result is weakness and paralysis of the muscle. The muscle atrophies. The blockage of acetylcholine release is irreversible. Function can be recovered by the sprouting of nerve terminals and the formation of new synaptic contacts, which usually takes 2 to 3 months.
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Bowel: Another name for the intestine . The small bowel and the large bowel are the small intestine and large intestine , respectively.
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Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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CBC: A commonly used abbreviation in medicine that stands for complete blood count , a set values of the cellular (formed elements) of blood. These measurements are generally determined by specially designed machines that analyze the different components of blood in less than a minute.
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Chest: The area of the body located between the neck and the abdomen . The chest contains the lungs , the heart and part of the aorta . The walls of the chest are supported by the dorsal vertebrae , the ribs , and the sternum .
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Complete blood count : A set values of the cellular (formed elements) of blood. These measurements are generally determined by specially designed machines that analyze the different components of blood in less than a minute.
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Computerized tomography: Pictures of structures within the body created by a computer that takes the data from multiple X-ray images and turns them in pictures.
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Condition: The term "condition" has a number of biomedical meanings including the following:

An unhealthy state, such as in "this is a progressive condition."
A state of fitness, such as "getting into condition."
Something that is essential to the occurrence of something else; essentially a "precondition."
As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

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Crutch: A wooden or metal vertical prop that helps support a disabled person while he or she is walking. Crutches extend from the walking surface to either the armpit or the arm.
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Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Disc: Shortened terminology for an intervertebral disc, a disk-shaped piece of specialized tissue that separates the bones of the spinal column.
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Emergency department: The department of a hospital responsible for the provision of medical and surgical care to patients arriving at the hospital in need of immediate care. Emergency department personnel may also respond to certain situations within the hospital such cardiac arrests.
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Feet: The plural of foot, both an anatomic structure and a unit of measure.
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Fever : Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
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Fibromyalgia: A syndrome characterized by chronic pain , stiffness, and tenderness of muscles, tendons, and joints without detectable inflammation . Fibromyalgia does not cause body damage or deformity. However, undue fatigue plagues the large majority of patients with fibromyalgia and sleep disorders are common in fibromyalgia.
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Fungus: A single-celled or multicellular organism. Fungi can be true pathogens (such as histoplasmosis and coccidioidomycosis ) that cause infections in healthy persons or they can be opportunistic pathogens (such as aspergillosis , candidiasis , and cryptococcosis) that cause infections in immunocompromised persons (including cancer patients, transplant recipients, and persons with AIDS ). An example of a common fungus is the yeast organism which causes thrush and diaper rash (diaper dermatitis ). Fungi are also used for the development of antibiotics, antitoxins, and other drugs used to control various human diseases.
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Herniated disc: Rupturing of the tissue that separates the vertebral bones of the spinal column.
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HIV: Acronym for the Human Immunodeficiency Virus , the cause of AIDS (acquired immunodeficiency syndrome). HIV has also been called the human lymphotropic virus type III, the lymphadenopathy-associated virus and the lymphadenopathy virus . No matter what name is applied, it is a retrovirus. (A retrovirus has an RNA genome and a reverse transcriptase enzyme. Using the reverse transcriptase , the virus uses its RNA as a template for making complementary DNA which can integrate into the DNA of the host organism).
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Hospital: It may seem unnecessary to define a "hospital" since everyone knows the nature of a hospital. A hospital began as a charitable institution for the needy, aged, infirm, or young.
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Ibuprofen: A non-steroidal anti-inflammatory drug (NSAID) commonly used to treat pain, swelling, and fever . Common brand names for Ibuprofen include Advil, Motrin, and Nuprin.
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Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response .
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Injury: Harm or hurt. The term "injury" may be applied in medicine to damage inflicted upon oneself as in a hamstring injury or by an external agent on as in a cold injury . The injury may be accidental or deliberate, as with a needlestick injury . The term "injury" may be synonymous (depending on the context) with a wound or with trauma .
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Joint: A joint is the area where two bones are attached for the purpose of motion of body parts. A joint is usually formed of fibrous connective tissue and cartilage. An articulation or an arthrosis is the same as a joint.
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Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.

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Kidney stone : A stone in the kidney (or lower down in the urinary tract).
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Knee: The knee is a joint which has three parts. The thigh bone (the femur) meets the large shin bone (the tibia) to form the main knee joint. This joint has an inner (medial) and an outer (lateral) compartment. The kneecap (the patella) joins the femur to form a third joint, called the patellofemoral joint. The patella protects the front of the knee joint.
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Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."
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Leg: In popular usage, the leg extends from the top of the thigh down to the foot. However, in medical terminology, the leg refers to the portion of the lower extremity from the knee to the ankle.
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Low back pain: Pain in the lower back area that can relate to problems with the lumbar spine , the discs between the vertebrae , the ligaments around the spine and discs, the spinal cord and nerves , muscles of the low back, internal organs of the pelvis and abdomen , or the skin covering the lumbar area.
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Lyme disease: Lyme disease is a bacterial illness caused by a bacterium called a "spirochete." Lyme disease is spread by ticks when they bite the skin. Lyme disease can cause abnormalities in the skin, joints, heart and nervous system.
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Magnetic resonance imaging : A special radiology technique designed to image internal structures of the body using magnetism, radio waves, and a computer to produce the images of body structures. In magnetic resonance imaging (MRI), the scanner is a tube surrounded by a giant circular magnet. The patient is placed on a moveable bed that is inserted into the magnet. The magnet creates a strong magnetic field that aligns the protons of hydrogen atoms, which are then exposed to a beam of radio waves. This spins the various protons of the body, and they produce a faint signal that is detected by the receiver portion of the MRI scanner. A computer processes the receiver information, and an image is produced. The image and resolution is quite detailed and can detect tiny changes of structures within the body, particularly in the soft tissue, brain and spinal cord, abdomen and joints.
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Massage: The manipulation of muscle and connective tissue to enhance the function of those tissues and promote relaxation and well-being. Therapeutic massage can ease tension and reduce pain. Massage can be a part of physical therapy or practiced on its own. It can also be highly effective for reducing the symptoms of arthritis , back pain, carpal tunnel syndrome, and other disorders of the muscles and/or nervous system.
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Medical history: 1. In clinical medicine, the patient's past and present which may contain clues bearing on their health past, present, and future. The medical history, being an account of all medical events and problems a person has experienced, including psychiatric illness, is especially helpful when a differential diagnosis is needed.
2. The history of medicine.
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Medication: 1. A drug or medicine. 2. The administration of a drug or medicine. (Note that "medication" does not have the dangerous double meaning of "drug.")
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Morphine: A powerful narcotic agent with strong analgesic (painkilling) action and other significant effects on the central nervous system . It is dangerously addicting. Morphine is a naturally occurring member of a large chemical class of compounds called alkaloids.
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MRI: Abbreviation and nickname for magnetic resonance imaging . For more information, see: Magnetic Resonance Imaging ; Paul C. Lauterbur ; Peter Mansfield .
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Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."
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Narcotic: 1. A drug that causes insensibility or stupor. A narcotic induces narcosis, from the Greek "narke" for "numbness or torpor."
2. A drug such as marijuana which is subject to regulatory restrictions comparable to those for addictive narcotics.
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Nerve: A bundle of fibers that uses chemical and electrical signals to transmit sensory and motor information from one body part to another. See: Nervous system .
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Nucleus: 1) In cell biology, the structure that houses the chromosomes. 2) In neuroanatomy, a group of nerve cells.
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Osteoarthritis: A type of arthritis caused by inflammation, breakdown, and eventual loss of cartilage in the joints. Also known as degenerative arthritis .
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Osteoporosis: Thinning of the bones with reduction in bone mass due to depletion of calcium and bone protein . Osteoporosis predisposes a person to fractures, which are often slow to heal and heal poorly. It is more common in older adults, particularly post-menopausal women; in patients on steroids; and in those who take steroidal drugs. Unchecked osteoporosis can lead to changes in posture , physical abnormality (particularly the form of hunched back known colloquially as " dowager's hump "), and decreased mobility.
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Pelvic: Having to do with the pelvis, the lower part of the abdomen, located between the hip bones.
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Pharmacy: A location where prescription drugs are sold. A pharmacy is, by law, constantly supervised by a licensed pharmacist.
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Physical therapy: A branch of rehabilitative health that uses specially designed exercises and equipment to help patients regain or improve their physical abilities. Physical therapists work with many types of patients, from infants born with musculoskeletal birth defects, to adults suffering from sciatica or the after- effects of injury, to elderly post-stroke patients.
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Piriformis muscle: A muscle that begins at the front surface of the sacrum (the V-shaped bone between the buttocks at the base of the spine) and passes through the greater sciatic notch to attach to the top of the thigh bone (femur) at its bony prominence called the greater trochanter. The gluteus maximus muscle covers over the piriformis muscle in the buttocks.
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Piriformis syndrome: Irritation of the sciatic nerve caused by compression of the nerve within the buttock by the piriformis muscle. Typically, the pain of the piriformis syndrome is increased by contraction of the piriformis muscle, prolonged sitting, or direct pressure applied to the muscle. Buttock pain is common. The piriformis syndrome is one of the causes of sciatica .
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Pus: A thick whitish-yellow fluid which results from the accumulation of white blood cells (WBCs), liquified tissue and cellular debris. Pus is commonly a site of infection or foreign material in the body.
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Reiter syndrome: A chronic form of inflammatory arthritis wherein the following three conditions are combined: (1) arthritis ; (2) inflammation of the eyes (conjunctivitis); and (3) inflammation of the genital, urinary or gastrointestinal systems.
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Rest: 1. Repose. Relaxation.
2. A fragment of embryonic tissue that has been retained after the period of embryonic development. Also called an embryonic rest.
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Scan: As a noun, the data or image obtained from the examination of organs or regions of the body by gathering information with a sensing device.
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Sciatic nerve: The largest nerve in the body, the sciatic nerve begins from nerve roots in the lumbar part of the spinal cord (in the low back) and extends through the buttock area to send nerve endings down to the legs.
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Sciatica : Pain resulting from irritation of the sciatic nerve, typically felt from the low back to behind the thigh and radiating down below the knee. While sciatica can result from a herniated disc directly pressing on the nerve, any cause of irritation or inflammation of this nerve can reproduce the painful symptoms of sciatica. Diagnosis is by observation of symptoms, physical and nerve testing, and sometimes by X-ray or MRI if a herniated disk is suspected.
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Sedimentation rate : A blood test that detects and monitors inflammation in the body. It measures the rate at which red blood cells (RBCs) in a test tube separate from blood serum over time, becoming sediment in the bottom of the test tube. The sedimentation rate increases with more inflammation. Also called the erythrocyte sedimentation rate. Abbreviated as sed rate or ESR.
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Sense: In biology and medicine, the faculty of sensory reception. The ability to convey specific types of external or internal stimuli to the brain and perceive them. Sensory reception occurs through a process known as transduction in which stimuli are converted into nerve impulses which are relayed to the brain.
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Shock: In medicine, shock is a critical condition brought on by a sudden drop in blood flow through the body. There is failure of the circulatory system to maintain adequate blood flow. This sharply curtails the delivery of oxygen and nutrients to vital organs. It also compromises the kidney and so curtails the removal of wastes from the body. Shock can be due to a number of different mechanisms including not enough blood volume (hypovolemic shock) and not enough output of blood by the heart (cardiogenic shock). The signs and symptoms of shock include low blood pressure (hypotension), overbreathing (hyperventilation), a weak rapid pulse, cold clammy grayish-bluish (cyanotic) skin, decreased urine flow (oliguria), and mental changes (a sense of great anxiety and foreboding, confusion and, sometimes, combativeness).
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Sign: Any objective evidence of disease. Gross blood in the stool is a sign of disease. It can be recognized by the patient, doctor, nurse, or others. In contrast, a symptom is, by its nature, subjective. Abdominal pain is a symptom. It is something only the patient can know.
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Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.

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Sleep : The body's rest cycle.
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Slipped disc: Rupturing of the tissue that separates the vertebral bones of the spinal column.
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Sore: 1. (adjective) A popular term for painful. I have sore fingers from typing dictionary terms. She has a sore throat . 2. (noun) A nondescript term for nearly any lesion of the skin or mucous membranes. He has a number of sores in his mouth.

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Spinal cord: The major column of nerve tissue that is connected to the brain and lies within the vertebral canal and from which the spinal nerves emerge. Thirty-one pairs of spinal nerves originate in the spinal cord: 8 cervical , 12 thoracic , 5 lumbar, 5 sacral, and 1 coccygeal. The spinal cord and the brain constitute the central nervous system ( CNS ). The spinal cord consists of nerve fibers that transmit impulses to and from the brain. Like the brain, the spinal cord is covered by three connective-tissue envelopes called the meninges . The space between the outer and middle envelopes is filled with cerebrospinal fluid ( CSF ), a clear colorless fluid that cushions the spinal cord against jarring shock. Also known simply as the cord.
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Spinal stenosis: Narrowing of the spaces in the spine, resulting in compression of the nerve roots or spinal cord by bony spurs or soft tissues, such as disks, in the spinal canal. This occurs most often in the lumbar spine (in the low back) but also occurs in the cervical spine (in the neck) and less often in the thoracic spine (in the upper back).
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Spondylolisthesis: Forward movement of one of the building blocks ( vertebrae ) of the spine in relation to an adjacent vertebra .
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Stenosis: A narrowing, as in:

aortic stenosis (narrowing of the aortic valve of the heart),
pulmonary stenosis (narrowing of the pulmonary valve of the heart),
pyloric stenosis (narrowing of the outlet of the stomach), and
spinal stenosis (narrowing of the vertebral canal).

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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Symptom: Any subjective evidence of disease. Anxiety, lower back pain , and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.
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Syndrome: A set of signs and symptoms that tend to occur together and which reflect the presence of a particular disease or an increased chance of developing a particular disease.
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Temple: An area just behind and to the side of the forehead and the eye, above the side of the check bone (the zygomatic arch) and in front of the ear.
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Therapy: The treatment of disease .
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Toilet: 1. In medicine, cleansing of a wound and the skin around it. 2. In obstetrics, cleansing of a woman just after childbirth. 3. In dentistry, the cleaning out of a cavity before a restoration. 4. A device for the disposal of urine and feces. Or the room containing such a device.
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Tomography: The process for generating a tomogram , a two-dimensional image of a slice or section through a three-dimensional object. Tomography achieves this remarkable result by simply moving an x-ray source in one direction as the x-ray film is moved in the opposite direction during the exposure to sharpen structures in the focal plane, while structures in other planes appear blurred. The tomogram is the picture; the tomograph is the apparatus; and tomography is the process.
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Toxin: One of a number of poisons produced by certain plants, animals, and bacteria.
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Tumor: An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be benign or malignant (cancerous). There are dozens of different types of tumors. Their names usually reflect the kind of tissue they arise in, and may also tell you something about their shape or how they grow. For example, a medulloblastoma is a tumor that arises from embryonic cells (a blastoma) in the inner part of the brain (the medulla). Diagnosis depends on the type and location of the tumor. Tumor marker tests and imaging may be used; some tumors can be seen (for example, tumors on the exterior of the skin) or felt (palpated with the hands).
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Tylenol: See: Acetaminophen .
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Urinalysis : A test that determines the content of the urine. Because urine removes toxins and excess liquids from the body, it can contain important clues. Urinalysis can be used to detect some types of disease, particularly in the case of metabolic disorders and kidney disease. It can also be used to uncover evidence of drug abuse .
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Urine: Liquid waste. The urine is a clear, transparent fluid. It normally has an amber color. The average amount of urine excreted in 24 hours is from 40 to 60 ounces (about 1,200 cubic centimeters). Chemically, the urine is mainly an aqueous (watery) solution of salt (sodium chloride) and substances called urea and uric acid. Normally, it contains about 960 parts of water to 40 parts of solid matter. Abnormally, it may contain sugar (in diabetes), albumen (a protein) (as in some forms of kidney disease), bile pigments (as in jaundice ), or abnormal quantities of one or another of its normal components.
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Virus: A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with errors (mutations)-this ability to mutate is responsible for the ability of some viruses to change slightly in each infected person, making treatment more difficult.
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X-ray: 1. High-energy radiation with waves shorter than those of visible light. X-rays possess the properties of penetrating most substances (to varying extents), of acting on a photographic film or plate (permitting radiography), and of causing a fluorescent screen to give off light (permitting fluoroscopy). In low doses X-rays are used for making images that help to diagnose disease, and in high doses to treat cancer . Formerly called a Roentgen ray. 2. An image obtained by means of X-rays.
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