Definition of Cor pulmonaleCor pulmonale: Heart disease that results from abnormally high resistance to the passage of blood through the lungs; it often leads to right heart failure. Cor is the Latin word for the heart. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=10670 Last Editorial Review: 6/14/2012
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