Definition of Bone cyst, simpleBone cyst, simple: A solitary fluid-filled cavity (cyst) in a bone, usually in the shaft of a long bone, especially the humerus, in a child. A simple bone cyst can cause pain in or near the bone. Also known as unicameral bone cyst and solitary bone cyst. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=11050 Last Editorial Review: 3/19/2012
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