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Definition of Headache, rebound

Headache, rebound: A headache experienced by someone who has taken pain relievers for migraines or other health conditions and has built up a tolerance for these medications. Often a rebound headache occurs right after the medication wears off. Treatment involves using the medication less frequently or switching to a different pain reliever.

Source: MedTerms™ Medical Dictionary
Last Editorial Review: 3/19/2012

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