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Definition of Subtelomeric

Subtelomeric: Below the telomere, the end of a chromosome.

For example, it has been reported that subtle subtelomeric rearrangements of the DNA are responsible for a significant proportion of unexplained cases of moderate to severe mental retardation (References: Lancet 1999;354:1659-1660,1676-1681).

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=11438
Last Editorial Review: 6/14/2012

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