Definition of Kleine-Levin syndrome

Kleine-Levin syndrome: A rare condition characterized by excessive need for sleep, food, and sexual disinhibition. Most people with Kleine-Levin syndrome are adolescent males. When awake, they may be confused, irritable, and lethargic, and some have hallucinations. The cause is unknown, although current theory holds that Kleine- Levin syndrome is caused by an inherited autosomal dominant trait that affects the hypothalamus gland. Most cases resolve over time without treatment.