Definition of OrgasmOrgasm: A series of muscle contractions in the genital region that is accompanied by sudden release of endorphins. Orgasm normally accompanies male ejaculation as a result of sexual stimulation, and it also occurs in females as a result of sexual stimulation. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=11783 Last Editorial Review: 3/19/2012
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