Definition of PlaquePlaque: 1. An semi-hardened accumulation of substances from fluids that bathe an area. Examples include dental plaque and cholesterol plaque.
2. In dermatology, a plaque is a patch of a small area of skin that appears different than the surrounding skin and is usually raised. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=11888 Last Editorial Review: 4/27/2011 5:27:15 PM
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