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May 19, 2013
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Definition of Major anomaly

Major anomaly: An unusual anatomic feature that is of serious medical or cosmetic consequence to the patient. For example, a major anomaly might be a cleft lip and palate.

By contrast, a minor anomaly is an unusual anatomic feature not of serious medical or cosmetic consequence to the patient. For example, a minor anomaly might be curvature of the second toe so it overlaps the third toe.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=12760
Last Editorial Review: 6/14/2012

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