Topiramate for Epilepsy
Topiramate comes in tablets and capsules, which can be opened and sprinkled on food.
How It Works
It is not known exactly how topiramate prevents seizures.
Why It Is Used
Topiramate may be used alone or in combination with other antiepileptic drugs to control partial seizures in children. It may also be used alone to treat children and adults with newly diagnosed epilepsy and generalized tonic-clonic seizures.
How Well It Works
Topiramate works to control partial and generalized tonic-clonic seizures.1
Common side effects of topiramate include:
Topiramate has been linked in a small number of people to a potentially life-threatening condition called metabolic acidosis. Symptoms of metabolic acidosis include fatigue, lack of appetite, and rapid breathing (hyperventilation). If left untreated, metabolic acidosis can lead to death.
The U.S. Food and Drug Administration (FDA) has issued a warning on antiepileptic medicines and the risk of suicide and suicidal thoughts. The FDA does not recommend that people stop using these medicines. Instead, people who take antiepileptic medicine should be watched closely for warning signs of suicide. People who take antiepileptic medicine and who are worried about this side effect should talk to a doctor.
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
It may take time and careful, controlled adjustments by you and your doctor to find the combination, schedule, and dosing of medicine to best manage your epilepsy. The goal is to prevent seizures while causing as few side effects as possible. After you and your doctor figure out the medicine program that works best for you, make sure to follow your program exactly as prescribed.
eMedicineHealth Medical Reference from Healthwise
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