Prostaglandin Analog to Prevent NSAID-Induced Peptic Ulcer
Arthrotec is a medicine that contains both an NSAID (diclofenac) and misoprostol.
How It Works
Misoprostol reduces the amount of acid produced by the stomach and enhances protection of the lining of the stomach and the upper small intestine (duodenum).
Why It Is Used
How Well It Works
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
Call your doctor right away if:
Common side effects of this medicine include:
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
The side effects of misoprostol are common and unpleasant. Because of this, using misoprostol is not always a good choice. Using an acid reducer (such as a proton pump inhibitor) along with NSAIDs to prevent peptic ulcers works just as well without the unpleasant side effects. Taking a lower dose of misoprostol may also help prevent ulcers but with fewer side effects.2
Taking misoprostol with food or milk can help prevent side effects such as diarrhea and stomach cramps.
Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.
There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.
Advice for women
Do not use this medicine if you are pregnant or planning to get pregnant. If you need to use this medicine, talk to your doctor about how you can prevent pregnancy.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
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