Test Overview

A blood glucose test measures the amount of a type of sugar, called glucose, in your blood. Glucose comes from carbohydrate foods. It is the main source of energy used by the body. Insulin is a hormone that helps your body's cells use the glucose. Insulin is produced in the pancreas and released into the blood when the amount of glucose in the blood rises.

Normally, your blood glucose levels increase slightly after you eat. This increase causes your pancreas to release insulin so that your blood glucose levels do not get too high. Blood glucose levels that remain high over time can damage your eyes, kidneys, nerves, and blood vessels.

There are several different types of blood glucose tests.

• Fasting blood sugar (FBS) measures blood glucose after you have not eaten for at least 8 hours. It is often the first test done to check for prediabetes and diabetes.
• 2-hour postprandial blood sugar measures blood glucose exactly 2 hours after you start eating a meal. This is not a test used to diagnose diabetes.
• Random blood sugar (RBS) measures blood glucose regardless of when you last ate. Several random measurements may be taken throughout the day. Random testing is useful because glucose levels in healthy people do not vary widely throughout the day. Blood glucose levels that vary widely may mean a problem. This test is also called a casual blood glucose test. Random testing is not used to diagnose diabetes.
• Oral glucose tolerance test is used to diagnose prediabetes and diabetes. An oral glucose tolerance test is a series of blood glucose measurements taken after you drink a sweet liquid that contains glucose. This test is commonly used to diagnose diabetes that occurs during pregnancy (gestational diabetes). This test is not commonly used to diagnose diabetes in a person who is not pregnant.
• Glycohemoglobin A1c measures how much sugar (glucose) is stuck to red blood cells. This test can be used to diagnose diabetes. It also shows how well your diabetes has been controlled in the last 2 to 3 months and whether your diabetes medicine needs to be changed. The result of your A1c test can be used to estimate your average blood sugar level. This is called your estimated average glucose, or eAG.

To make a diagnosis of type 2 diabetes, your doctor will use the American Diabetes Association's criteria.

Why It Is Done

Blood glucose tests are done to:

• Check for diabetes.
• Monitor treatment of diabetes.
• Check for diabetes that occurs during pregnancy (gestational diabetes).
• Determine if an abnormally low blood sugar level (hypoglycemia) is present. A test to measure blood levels of insulin and a protein called C-peptide may be done along with a blood glucose test to determine the cause of hypoglycemia. For more information, see the topic C-Peptide.

Fasting blood glucose tests are done to detect the risk of diabetes (prediabetes) when glucose levels are 110–125 mg/dL (5.6–6.9 mmol/L), as recommended by the American Diabetes Association.¹

How To Prepare

Fasting blood sugar (FBS)

For a fasting blood sugar test, do not eat or drink anything other than water for at least 8 hours before the blood sample is taken.

If you have diabetes, you may be asked to wait until you have had your blood tested before taking your morning dose of insulin or diabetes medicine.

2-hour postprandial blood sugar

For a 2-hour postprandial test, start eating a meal exactly 2 hours before the blood sample is taken. A home blood sugar test is the most common way to check 2-hour postprandial blood sugar levels.

Random blood sugar (RBS)

No special preparation is required before having a random blood sugar test.

Oral glucose tolerance test and glycohemoglobin A1c

For information on preparing for an oral glucose tolerance test or glycohemoglobin A1c test, see the topic Oral Glucose Tolerance Test or Glycohemoglobin A1c for more information.

Talk to your doctor about any concerns you have regarding the need for the test, its risks, how it will be done, or what the results may mean. To help you understand the importance of this test, fill out the medical test information form(What is a PDF document?).

How It Is Done

The health professional taking a sample of your blood will:

• Wrap an elastic band around your upper arm to stop the flow of blood. This makes the veins below the band larger so it is easier to put a needle into the vein.
• Clean the needle site with alcohol.
• Put the needle into the vein. More than one needle stick may be needed.
• Attach a tube to the needle to fill it with blood.
• Remove the band from your arm when enough blood is collected.
• Apply a gauze pad or cotton ball over the needle site as the needle is removed.
• Apply pressure to the site and then a bandage.

How It Feels

The blood sample is taken from a vein in your arm. An elastic band is wrapped around your upper arm. It may feel tight. You may feel nothing at all from the needle, or you may feel a quick sting or pinch.

Risks

There is very little risk of a problem from having blood drawn from a vein.

• You may develop a small bruise at the puncture site. You can reduce the risk of bruising by keeping pressure on the site for several minutes after the needle is withdrawn.
• In rare cases, the vein may become inflamed after the blood sample is taken. This condition is called phlebitis and is usually treated with a warm compress applied several times daily.
• Continued bleeding can be a problem for people with bleeding disorders. Aspirin, warfarin (Coumadin), and other blood-thinning medicines can also make bleeding more likely. If you have bleeding or clotting problems, or if you take blood-thinning medicine, tell your health professional before your blood is drawn.

Results

Normal

A blood glucose test measures the amount of a type of sugar, called glucose, in your blood.

Results are often ready in 1 to 2 hours. Glucose levels in a blood sample taken from your vein (called a blood plasma value) may differ a little than glucose levels checked with a finger stick.

The normal values listed here—called a reference range—are just a guide. These ranges vary from lab to lab, and your lab may have a different range for what's normal. Your lab report should contain the range your lab uses. Also, your doctor will evaluate your results based on your health and other factors. This means that a value that falls outside the normal values listed here may still be normal for you or your lab.

Many conditions can change your blood glucose levels. Your doctor will discuss any significant abnormal results with you in relation to your symptoms and past health.

For more information on results from an oral glucose tolerance test or glycohemoglobin A1c test, see the topic Oral Glucose Tolerance Test or Glycohemoglobin A1c.

High values

You may have diabetes. To make a diagnosis of type 2 diabetes, your doctor will use the American Diabetes Association's criteria.

Other conditions that can cause high blood glucose levels include:

• Severe stress.
• Heart attack.
• Stroke.
• Cushing's syndrome.
• Medicines such as corticosteroids.
• Excess production of growth hormone (acromegaly).

Low values

A fasting glucose level below 40 mg/dL (2.2 mmol/L) in women or below 50 mg/dL (2.8 mmol/L) in men that is accompanied by symptoms of hypoglycemia may mean you have an insulinoma, a tumor that produces abnormally high amounts of insulin.

Low glucose levels also may be caused by:

• Addison's disease.
• Decreased thyroid hormone levels (hypothyroidism).
• A tumor in the pituitary gland.
• Liver disease, such as cirrhosis.
• Kidney failure.
• Malnutrition or an eating disorder, such as anorexia.
• Medicines used to treat diabetes.

What Affects the Test

Reasons you may not be able to have the test or why the results may not be helpful include:

• Eating or drinking less than 8 hours before a fasting blood test or less than 2 hours before a 2-hour postprandial test.
• Drinking alcohol.
• Illness or emotional stress, smoking, and caffeine.
• Taking a medicine, such as birth control pills, medicines used to treat high blood pressure, phenytoin (Dilantin), furosemide (Lasix), triamterene (Dyrenium, Dyazide), hydrochlorothiazide (Esidrix, Oretic), niacin, propranolol (Inderal), or corticosteroids (prednisone). Some medicines can cause changes in your test results. Make sure that your doctor knows about any medicines you take and how often you take them.

What To Think About

• Glucose levels in urine can also be measured. Many people with diabetes have glucose in their urine. But the level in the blood must be very high before glucose can be detected in the urine. For this reason, tests for glucose in urine are not used to diagnose or monitor diabetes. For more information, see the topic Urine Test.
• If you have diabetes, you will be able to measure your blood glucose levels at home. For more information, see the topic Home Blood Glucose Test.

References

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