Skin Cancer Prevention (Professional) (cont.)
IN THIS ARTICLE
Interventions With Inadequate Evidence as to Whether They Reduce Risk of Nonmelanoma Skin Cancer
Sunscreen Use and Ultraviolet (UV) Radiation Avoidance
The evidence that interventions designed to reduce exposure to UV radiation by the use of sunscreen, protective clothing, or limitation of sun exposure time decrease the incidence of nonmelanoma skin cancer is inadequate. A randomized study suggested a possible reduction in incidence of squamous cell carcinomas (SCCs), but study design and analysis problems complicate interpretation of the results.[1,2]
Magnitude of Benefit: Not applicable (N/A) (inadequate evidence).
The harms of sunscreen use are poorly quantified but are likely to be small, including allergic reactions to skin creams and lower production of vitamin D by the skin with less sun exposure.
There is inadequate evidence to determine whether the use of chemopreventive agents reduces the incidence of SCC or BCC of the skin.
Magnitude of Effect: N/A (inadequate evidence).
Beta carotene use has been associated in RCTs with an increased risk of lung cancer incidence and mortality in smokers. Isotretinoin has dose-related skin toxicity. COX-2 inhibitors, such as celecoxib, have been associated with cardiac toxicity in RCTs for the prevention of colorectal cancer.
eMedicineHealth Public Information from the National Cancer Institute
This information is produced and provided by the National Cancer Institute (NCI). The information in this topic may have changed since it was written. For the most current information, contact the National Cancer Institute via the Internet web site at http://cancer.gov or call 1-800-4-CANCER
This information is not intended to replace the advice of a doctor. Healthwise disclaims any liability for the decisions you make based on this information.
Some material in CancerNet™ is from copyrighted publications of the respective copyright claimants. Users of CancerNet™ are referred to the publication data appearing in the bibliographic citations, as well as to the copyright notices appearing in the original publication, all of which are hereby incorporated by reference.
- Early Care for Your Premature Baby
- What to Eat When You Have Cancer
- When to Take More Pain Medication