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Islet Cells and Islet Cell Antibodies


Islet cells are located in the pancreas and make hormones including insulin, glucagon, somatomammotropin, and pancreatic polypeptide. In some people, the immune system produces islet cell antibodies, which attack and destroy the islet cells as though they were foreign substances; this can lead to serious health conditions, such as type 1 diabetes.

ByHealthwise Staff
Primary Medical ReviewerJohn Pope, MD - Pediatrics
Specialist Medical ReviewerDavid C.W. Lau, MD, PhD, FRCPC - Endocrinology
Last RevisedSeptember 14, 2010

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