Lipid disorders are problems that affect the way cholesterol is produced, used, carried in the blood, or disposed of by the body. People with lipid disorders develop very high total cholesterol levels, very low HDL (or "good") cholesterol levels, and/or high triglyceride levels.

Lipid disorders are often inherited. People who have lipid disorders are usually at risk of developing coronary artery disease, often at an early age.

If a person is known to have a lipid disorder, treatment can be started early to lower the person's cholesterol, and family members can be made aware that they may also be at risk.

Examples of inherited lipid disorders include familial combined hyperlipidemia and familial hypercholesterolemia.