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Medicines That May Cause a Rash

Medicines That May Cause a Rash

Many medicines can cause a rash. Some of the more common medicines that cause rashes are:

  • Angiotensin-converting enzyme (ACE) inhibitors for high blood pressure, such as captopril, enalapril, fosinopril, or lisinopril.
  • Antibiotics, such as penicillin, cephalosporins, sulfonamides, furadantin, or vancomycin.
  • Anticonvulsants, such as carbamazepine or valproate.
  • Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen.
  • Barbiturates, such as amobarbital or pentobarbital.
  • Blood and blood products.
  • Complementary and alternative medicines, such as echinacea.
  • Contrast dyes used in X-ray studies.
  • Enzymes, such as trypsin and streptokinase.
  • Pain medicines that contain codeine and codeine-like compounds.
  • Phenylbutazone, such as Azolid, Butatab, Butazolidin, Butazone-100, or Phenylbutazone Alka.
  • Sulfonamide derivatives, such as hydrochlorothiazide.

If a rash occurs after you have begun a new medicine:

  • Call the doctor who prescribed the medicine to determine whether you should stop taking the medicine or take a different one. An appointment may not be necessary. Do not take another dose of the medicine until you have spoken to your doctor.
  • If you are taking a nonprescription medicine, stop taking it. Call your doctor if you feel you need to continue taking the medicine.


ByHealthwise Staff
Primary Medical ReviewerWilliam H. Blahd, Jr., MD, FACEP - Emergency Medicine
Specialist Medical ReviewerDavid Messenger, MD
Last RevisedJuly 20, 2010

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