Danazol for Premenstrual Dysphoric Disorder (PMDD)
Danazol is a synthetic form of the male hormone testosterone.
How It Works
This medicine (called a hormone suppressor) decreases production of the hormone estrogen. This decrease stops the monthly menstrual hormone cycle, which relieves premenstrual dysphoric disorder (PMDD) symptoms.
Why It Is Used
Danazol is used to treat symptoms of PMDD if other treatments have failed to end severe symptoms.
How Well It Works
Danazol may relieve the irritability, anxiety, lethargy, increased appetite, headaches, and breast tenderness that occur with PMS and PMDD. Unfortunately, the side effects of treatment with danazol outweigh the benefits for many women. Many women stop taking this medicine because of its side effects.
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
Call your doctor if you have:
Common side effects of this medicine include:
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
Danazol may cause your skin to be more sensitive to sunlight. When you are taking this medicine:
Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.
There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.
Advice for women
Do not use this medicine if you are pregnant, breast-feeding, or planning to get pregnant. If you need to take this medicine, talk to your doctor about how you can prevent pregnancy.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
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