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Anticoagulants for Heart Attack and Unstable Angina


Examples

Unfractionated heparin

Generic NameBrand Name
heparinHeparin, Fragmin, Lovenox, Innohep, Angiomax, Arixtra, Refludan

Low-molecular-weight heparins

Generic NameBrand Name
dalteparinFragmin, Lovenox, Innohep, Angiomax, Arixtra, Refludan
enoxaparinFragmin, Lovenox, Innohep, Angiomax, Arixtra, Refludan
tinzaparinFragmin, Lovenox, Innohep, Angiomax, Arixtra, Refludan

Direct thrombin inhibitors

Generic NameBrand Name
bivalirudinAngiomax, Arixtra, Refludan
fondaparinuxAngiomax, Arixtra, Refludan
lepirudinAngiomax, Arixtra, Refludan

How It Works

Anticoagulants are often called "blood thinners," although they don't really thin blood. They decrease the blood's ability to clot.

Why It Is Used

Anticoagulants are given in the hospital during unstable angina or a heart attack, because they can prevent clots from becoming larger and blocking coronary arteries. They are often given with other anticlotting medicines to help prevent or reduce heart muscle damage.

How Well It Works

Anticoagulants can help prevent another heart attack and lower the risk of dying soon after a heart attack.1

Side Effects

Anticoagulants for a heart attack are given in the hospital. So a person is watched closely for any side effects.

The most common side effect is bleeding inside the body.

See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)

What To Think About

Anticoagulants might be used after a person goes home from the hospital after a heart attack. These medicines can lower the risk of another heart attack, and they can lower the risk of stroke. For this long-term use, another type of anticoagulant, such as warfarin, is typically used.

When you take anticoagulants at home, you need to take extra steps to avoid bleeding problems. If you take warfarin, see:

Click here to view an Actionset.Warfarin: Taking Your Medicine Safely.

Complete the new medication information form (PDF)Click here to view a form.(What is a PDF document?) to help you understand this medication.

References

Citations

  1. O'Connor RE, et al. (2010). Acute coronary syndromes: 2010 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation, 122(18): S787–S817.

Credits

ByHealthwise Staff
Primary Medical ReviewerKathleen Romito, MD - Family Medicine
Primary Medical ReviewerE. Gregory Thompson, MD - Internal Medicine
Specialist Medical ReviewerStephen Fort, MD, MRCP, FRCPC - Interventional Cardiology
Last RevisedApril 29, 2011

eMedicineHealth Medical Reference from Healthwise

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